1D1N
 
 | | SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2 | | Descriptor: | INITIATION FACTOR 2 | | Authors: | Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M. | | Deposit date: | 1999-09-20 | | Release date: | 2000-09-20 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
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1B23
 | | E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex | | Descriptor: | CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ... | | Authors: | Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J. | | Deposit date: | 1998-12-04 | | Release date: | 1998-12-07 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
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1AIP
 | | EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS | | Descriptor: | ELONGATION FACTOR TS, ELONGATION FACTOR TU | | Authors: | Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B. | | Deposit date: | 1997-04-22 | | Release date: | 1997-10-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
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3MMP
 | | Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | | Descriptor: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | | Authors: | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | | Deposit date: | 2010-04-20 | | Release date: | 2010-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5FG3
 | | Crystal structure of GDP-bound aIF5B from Aeropyrum pernix | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Probable translation initiation factor IF-2 | | Authors: | Murakami, R, Miyoshi, T, Uchiumi, T, Ito, K. | | Deposit date: | 2015-12-20 | | Release date: | 2016-05-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of translation initiation factor 5B from the crenarchaeon Aeropyrum pernix.
Proteins, 84, 2016
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5O8W
 | | CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | | Descriptor: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | | Authors: | Wirth, C, Andersen, G.R, Hunte, C. | | Deposit date: | 2017-06-14 | | Release date: | 2017-08-23 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
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5O9Z
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5OPD
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5OT7
 | | Elongation factor G-ribosome complex captures in the absence of inhibitors. | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Mace, K, Giudice, E, Chat, S, Gillet, R. | | Deposit date: | 2017-08-21 | | Release date: | 2018-02-14 | | Last modified: | 2018-04-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
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7CSL
 | | Crystal structure of the archaeal EF1A-EF1B complex | | Descriptor: | Elongation factor 1-alpha, Elongation factor 1-beta | | Authors: | Suzuki, T, Ito, K, Miyoshi, T, Murakami, R, Uchiumi, T. | | Deposit date: | 2020-08-15 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural insights into the Switching Off of the Interaction between the Archaeal Ribosomal Stalk and aEF1A by Nucleotide Exchange Factor aEF1B.
J.Mol.Biol., 433, 2021
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7CDW
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7D43
 | | eIF2B-eIF2(aP), aPg complex | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | Authors: | Kashiwagi, K, Ito, T. | | Deposit date: | 2020-09-22 | | Release date: | 2020-12-09 | | Last modified: | 2021-01-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
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7DVQ
 | | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | | Authors: | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | | Deposit date: | 2021-01-14 | | Release date: | 2021-03-31 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of the activated human minor spliceosome.
Science, 371, 2021
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1SKQ
 | | The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP | | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Vitagliano, L, Ruggiero, A, Masullo, M, Cantiello, P, Arcari, P, Zagari, A. | | Deposit date: | 2004-03-05 | | Release date: | 2004-07-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP.
Biochemistry, 43, 2004
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7F66
 | | eIF2B-SFSV NSs-1-eIF2 | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | Authors: | Kashiwagi, K, Ito, T. | | Deposit date: | 2021-06-24 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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7F67
 | | eIF2B-SFSV NSs-2-eIF2 | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | Authors: | Kashiwagi, K, Ito, T. | | Deposit date: | 2021-06-24 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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2FX3
 | | Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set | | Descriptor: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Heffron, S.E, Moeller, R, Jurnak, F. | | Deposit date: | 2006-02-03 | | Release date: | 2006-03-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
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1U2R
 | | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | | Deposit date: | 2004-07-20 | | Release date: | 2004-09-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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1TUI
 | | INTACT ELONGATION FACTOR TU IN COMPLEX WITH GDP | | Descriptor: | ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Polekhina, G, Thirup, S, Kjeldgaard, M, Nissen, P, Lippmann, C, Nyborg, J. | | Deposit date: | 1996-05-23 | | Release date: | 1997-06-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Helix unwinding in the effector region of elongation factor EF-Tu-GDP.
Structure, 4, 1996
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1TTT
 | | Phe-tRNA, elongation factoR EF-TU:GDPNP ternary complex | | Descriptor: | MAGNESIUM ION, OF ELONGATION FACTOR TU (EF-TU), PHENYLALANINE, ... | | Authors: | Nissen, P, Kjeldgaard, M, Thirup, S, Polekhina, G, Reshetnikova, L, Clark, B.F.C, Nyborg, J. | | Deposit date: | 1995-11-16 | | Release date: | 1996-12-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science, 270, 1995
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2H5E
 | | Crystal structure of E.coli polypeptide release factor RF3 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor RF-3 | | Authors: | Song, H.W, Zhou, Z.H. | | Deposit date: | 2006-05-26 | | Release date: | 2007-05-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
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2HDN
 | | Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution | | Descriptor: | Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. | | Deposit date: | 2006-06-20 | | Release date: | 2006-10-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
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2HCJ
 | | Trypsin-modified Elongation Factor Tu in complex with tetracycline | | Descriptor: | GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. | | Deposit date: | 2006-06-16 | | Release date: | 2006-10-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
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7L20
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2J7K
 | | Crystal structure of the T84A mutant EF-G:GDPCP complex | | Descriptor: | ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Hansson, S, Logan, D.T. | | Deposit date: | 2006-10-12 | | Release date: | 2007-10-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | New Insights Into the Role of the P-Loop Lysine: Implications from the Crystal Structure of a Mutant EF-G:Gdpcp Complex
To be Published
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