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3NPE
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BU of 3npe by Molmil
Structure of VP14 in complex with oxygen
Descriptor: 1,4-DIETHYLENE DIOXIDE, 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic, ...
Authors:Messing, S.A, Gabelli, S.B, Amzel, L.M.
Deposit date:2010-06-28
Release date:2010-11-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.
Plant Cell, 22, 2010
4ZHK
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BU of 4zhk by Molmil
Crystal structure of RPE65 in complex with MB-002
Descriptor: (1R)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, (1S)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, FE (II) ION, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2015-04-25
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
7QR6
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BU of 7qr6 by Molmil
Stilbene dioxygenase (NOV1) from Novosphingobium aromaticivorans: Ser283Phe mutant
Descriptor: Dioxygenase, FE (III) ION, OXYGEN MOLECULE
Authors:Alvigini, L, Mattevi, A.
Deposit date:2022-01-10
Release date:2022-08-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin.
Biochemistry, 62, 2023
3FSN
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BU of 3fsn by Molmil
Crystal structure of RPE65 at 2.14 angstrom resolution
Descriptor: FE (II) ION, Retinal pigment epithelium-specific 65 kDa protein, TETRAETHYLENE GLYCOL
Authors:Kiser, P.D, Lodowski, D.T, Palczewski, K.
Deposit date:2009-01-11
Release date:2009-09-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Proc.Natl.Acad.Sci.USA, 106, 2009
8DOC
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BU of 8doc by Molmil
Crystal structure of RPE65 in complex with compound 16e and palmitate
Descriptor: (1R)-1-[3-(cyclohexylmethoxy)phenyl]-3-(methylamino)propan-1-ol, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FE (II) ION, ...
Authors:Bassetto, M, Kiser, P.D.
Deposit date:2022-07-12
Release date:2023-05-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif.
J.Med.Chem., 66, 2023
7T8P
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BU of 7t8p by Molmil
CRYSTAL STRUCTURE OF T151V CAO1
Descriptor: CHLORIDE ION, Carotenoid oxygenase 1, FE (II) ION
Authors:Daruwalla, A, Kiser, P.D.
Deposit date:2021-12-16
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CRYSTAL STRUCTURE OF T151V CAO1
To Be Published
7T8Q
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BU of 7t8q by Molmil
CRYSTAL STRUCTURE OF T151G CAO1
Descriptor: CHLORIDE ION, Carotenoid oxygenase 1, FE (II) ION
Authors:Daruwalla, A, Kiser, P.D.
Deposit date:2021-12-16
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:CRYSTAL STRUCTURE OF T151G CAO1
To Be Published
8FTY
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BU of 8fty by Molmil
Crystal structure of the carotenoid isomerooxygenase, NinaB
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, CHLORIDE ION, ...
Authors:Kiser, P.D, Solano, Y.J.
Deposit date:2023-01-14
Release date:2024-01-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Carotenoid cleavage enzymes evolved convergently to generate the visual chromophore.
Nat.Chem.Biol., 2024
2BIX
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BU of 2bix by Molmil
Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, Fe-free apoenzyme
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, APOCAROTENOID-CLEAVING OXYGENASE, GLYCEROL
Authors:Kloer, D.P, Ruch, S, Al-Babili, S, Beyer, P, Schulz, G.E.
Deposit date:2005-01-26
Release date:2005-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:The Structure of a Retinal-Forming Carotenoid Oxygenase
Science, 308, 2005
2BIW
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BU of 2biw by Molmil
Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, native enzyme
Descriptor: (3R)-3-HYDROXY-8'-APOCAROTENOL, APOCAROTENOID-CLEAVING OXYGENASE, FE (III) ION
Authors:Kloer, D.P, Ruch, S, Al-Babili, S, Beyer, P, Schulz, G.E.
Deposit date:2005-01-26
Release date:2005-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:The Structure of a Retinal-Forming Carotenoid Oxygenase
Science, 308, 2005
4OU9
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BU of 4ou9 by Molmil
Crystal structure of apocarotenoid oxygenase in the presence of Triton X-100
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Sui, X, Palczewski, K, Kiser, P.D.
Deposit date:2014-02-15
Release date:2014-03-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO).
J.Biol.Chem., 289, 2014
4OU8
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BU of 4ou8 by Molmil
Crystal structure of apocarotenoid oxygenase in the presence of C8E6
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Sui, X, Shi, W, Palczewski, K, Kiser, P.D.
Deposit date:2014-02-15
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO).
J.Biol.Chem., 289, 2014
3KVC
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BU of 3kvc by Molmil
Crystal structure of bovine RPE65 at 1.9 angstrom resolution
Descriptor: FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Lodowski, D.T, Golczak, M, Palczewski, K.
Deposit date:2009-11-29
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Importance of membrane structural integrity for RPE65 retinoid isomerization activity.
J.Biol.Chem., 285, 2010
6B86
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BU of 6b86 by Molmil
2.2A Crystal Structure of Co-CAO1
Descriptor: COBALT (II) ION, Carotenoid oxygenase 1
Authors:Hill, H.E, Kiser, P.D.
Deposit date:2017-10-05
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.
J. Biol. Inorg. Chem., 23, 2018
6BIG
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BU of 6big by Molmil
Crystal structure of cobalt-substituted Synechocystis ACO
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, COBALT (II) ION
Authors:Sui, X, Shi, W, Kiser, P.D.
Deposit date:2017-11-02
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.
J. Biol. Inorg. Chem., 23, 2018
6C7K
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BU of 6c7k by Molmil
Crystal structure of an ACO/RPE65 chimera
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-22
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
6C7P
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BU of 6c7p by Molmil
Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
6C7O
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BU of 6c7o by Molmil
Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form
Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
7VUD
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BU of 7vud by Molmil
Carotenoid Cleavage Dioxygenase 1 from Osmanthus fragrans
Descriptor: Carotenoid cleavage dioxygenase 1, NICKEL (II) ION, OXTOXYNOL-10, ...
Authors:Sharma, D, Xue, B.
Deposit date:2021-11-02
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Carotenoid Cleavage Dioxygenase 1 from Osmanthus fragrans
To Be Published
7WH0
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BU of 7wh0 by Molmil
structure of C elegans BCMO-1
Descriptor: Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ...
Authors:Pan, W, Liu, L.
Deposit date:2021-12-29
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Front Mol Biosci, 9, 2022
7WH1
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BU of 7wh1 by Molmil
structure of C elegans BCMO-2
Descriptor: Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ...
Authors:Pan, W, Liu, L.
Deposit date:2021-12-29
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Front Mol Biosci, 9, 2022
5J54
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BU of 5j54 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
Descriptor: Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ...
Authors:McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
Deposit date:2016-04-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6VCG
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BU of 6vcg by Molmil
Crystal structure of Nitrosotalea devanaterra carotenoid cleavage dioxygenase, cobalt form
Descriptor: CHLORIDE ION, COBALT (II) ION, SODIUM ION, ...
Authors:Daruwalla, A, Shi, W, Kiser, P.D.
Deposit date:2019-12-20
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase.
Proc.Natl.Acad.Sci.USA, 117, 2020
5J55
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BU of 5j55 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, Carotenoid oxygenase, FE (III) ION, ...
Authors:McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
Deposit date:2016-04-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5J53
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BU of 5j53 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
Descriptor: Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ...
Authors:McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
Deposit date:2016-04-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016

 

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