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1TAF
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BU of 1taf by Molmil
DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER
Descriptor: TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION
Authors:Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K.
Deposit date:1996-06-01
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature, 380, 1996
5FUR
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BU of 5fur by Molmil
Structure of human TFIID-IIA bound to core promoter DNA
Descriptor: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ...
Authors:Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E.
Deposit date:2016-01-29
Release date:2016-04-06
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
6F3T
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BU of 6f3t by Molmil
Crystal structure of the human TAF5-TAF6-TAF9 complex
Descriptor: CHLORIDE ION, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, ...
Authors:Haffke, M, Berger, I.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.
Nat. Struct. Mol. Biol., 25, 2018
6HQA
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BU of 6hqa by Molmil
Molecular structure of promoter-bound yeast TFIID
Descriptor: Histone-fold, Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation, ...
Authors:Kolesnikova, O, Ben-Shem, A, Luo, J, Ranish, J, Schultz, P, Papai, G.
Deposit date:2018-09-24
Release date:2018-11-21
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Molecular structure of promoter-bound yeast TFIID.
Nat Commun, 9, 2018
6MZC
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BU of 6mzc by Molmil
Human TFIID BC core
Descriptor: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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BU of 6mzm by Molmil
Human TFIID bound to promoter DNA and TFIIA
Descriptor: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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BU of 6mzd by Molmil
Human TFIID Lobe A canonical
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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BU of 6mzl by Molmil
Human TFIID canonical state
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6T9K
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BU of 6t9k by Molmil
SAGA Core module
Descriptor: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6T9I
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BU of 6t9i by Molmil
cryo-EM structure of transcription coactivator SAGA
Descriptor: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6TB4
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BU of 6tb4 by Molmil
Structure of SAGA bound to TBP
Descriptor: SAGA-associated factor 73 (Sgf73), Spt20, Subunit (17 kDa) of TFIID and SAGA complexes, ...
Authors:Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A.
Deposit date:2019-10-31
Release date:2020-01-29
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
6TBM
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BU of 6tbm by Molmil
Structure of SAGA bound to TBP, including Spt8 and DUB
Descriptor: Polyubiquitin-B, SAGA-associated factor 11, Spt20, ...
Authors:Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A.
Deposit date:2019-11-01
Release date:2020-02-12
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
7KTR
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BU of 7ktr by Molmil
Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core)
Descriptor: Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ...
Authors:Herbst, D.A, Esbin, M.N, Nogales, E.
Deposit date:2020-11-24
Release date:2021-11-10
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
7KTS
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BU of 7kts by Molmil
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Descriptor: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ...
Authors:Herbst, D.A, Esbin, M.N, Nogales, E.
Deposit date:2020-11-24
Release date:2021-11-10
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (19.09 Å)
Cite:Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
7EDX
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BU of 7edx by Molmil
p53-bound TFIID-based core PIC on HDM2 promoter
Descriptor: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-17
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG9
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BU of 7eg9 by Molmil
TFIID-based intermediate PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG7
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BU of 7eg7 by Molmil
TFIID-based core PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGF
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BU of 7egf by Molmil
TFIID lobe A subcomplex
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 2021
7EG8
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BU of 7eg8 by Molmil
TFIID-based core PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGA
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BU of 7ega by Molmil
TFIID-based intermediate PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGG
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BU of 7egg by Molmil
TFIID lobe B subcomplex
Descriptor: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGH
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BU of 7egh by Molmil
TFIID lobe C subcomplex
Descriptor: DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGI
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BU of 7egi by Molmil
TFIID in rearranged conformation
Descriptor: TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (9.82 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGD
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BU of 7egd by Molmil
SCP promoter-bound TFIID-TFIIA in initial TBP-loading state
Descriptor: DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (6.75 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGB
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BU of 7egb by Molmil
TFIID-based holo PIC on SCP promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021

 

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