PDB: 61 resultsInfo pagesStatus searchChemie searchBIRD

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7QY7	Proteasome-ZFAND5 Complex Z-A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QYA	Proteasome-ZFAND5 Complex Z-B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXW	Proteasome-ZFAND5 Complex Z+D state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXU	Proteasome-ZFAND5 Complex Z+C state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXN	Proteasome-ZFAND5 Complex Z+A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QYB	Proteasome-ZFAND5 Complex Z-C state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXX	Proteasome-ZFAND5 Complex Z+E state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXP	Proteasome-ZFAND5 Complex Z+B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
8CVT	Human 19S-20S proteasome, state SD2 Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Zhao, J. Deposit date: 2022-05-18 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
7W3M	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3I	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3H	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3J	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3A	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3K	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
6WJD	SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Chen, X, Walters, K.J. Deposit date: 2020-04-13 Release date: 2020-08-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
6MUN	Structure of hRpn10 bound to UBQLN2 UBL Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2 Authors: Chen, X, Walters, K.J. Deposit date: 2018-10-23 Release date: 2019-09-04 Last modified: 2019-12-04 Method: SOLUTION NMR Cite: Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome. J.Mol.Biol., 431, 2019
6NJG	Ubiquitin Variant in Complex with Ubiquitin Interacting Motif Descriptor: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27 Authors: Manczyk, N, Sicheri, F. Deposit date: 2019-01-03 Release date: 2019-03-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif. Protein Sci., 28, 2019

 

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