6EPF
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GROUND STATE 26S PROTEASOME (GS1)
Descriptor:3, 6, 12, ...
Authors:Guo, Q., Lehmer, C., Martinez-Sanchez, A., Rudack, T., Beck, F., Hartmann, H., Hipp, M.S., Hartl, F.U., Edbauer, D., Baumeister, W., Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2018-02-21
Method:ELECTRON MICROSCOPY (11.8 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPE
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SUBSTRATE PROCESSING STATE 26S PROTEASOME (SPS2)
Descriptor:3, 6, 12, ...
Authors:Guo, Q., Lehmer, C., Martinez-Sanchez, A., Rudack, T., Beck, F., Hartmann, H., Hipp, M.S., Hartl, F.U., Edbauer, D., Baumeister, W., Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2018-02-21
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPD
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SUBSTRATE PROCESSING STATE 26S PROTEASOME (SPS1)
Descriptor:3, 6, 12, ...
Authors:Guo, Q., Lehmer, C., Martinez-Sanchez, A., Rudack, T., Beck, F., Hartmann, H., Hipp, M.S., Hartl, F.U., Edbauer, D., Baumeister, W., Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2018-02-21
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPC
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GROUND STATE 26S PROTEASOME (GS2)
Descriptor:3, 6, 12, ...
Authors:Guo, Q., Lehmer, C., Martinez-Sanchez, A., Rudack, T., Beck, F., Hartmann, H., Hipp, M.S., Hartl, F.U., Edbauer, D., Baumeister, W., Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2018-02-21
Method:ELECTRON MICROSCOPY (12.3 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
5UCL
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UBIQUITIN VARIANT IN COMPLEX WITH BINDING PARTNER
Descriptor:Polyubiquitin-B, Vacuolar protein sorting-associated protein 27
Authors:Manczyk, N., Sicheri, F.
Deposit date:2016-12-22
Release date:2017-03-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif.
Protein Sci., 26, 2017
5T0J
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 2, Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0I
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 7, 26S protease regulatory subunit 4, 26S protease regulatory subunit 8, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0H
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 7, 26S protease regulatory subunit 4, 26S protease regulatory subunit 8, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0G
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0C
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-15
Release date:2016-10-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5O71
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CRYSTAL STRUCTURE OF HUMAN USP25
Descriptor:Ubiquitin carboxyl-terminal hydrolase 25
Authors:Reverter, D., Liu, B.
Deposit date:2017-06-07
Release date:2018-06-20
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:Crystal structure of human USP25
To Be Published
5M32
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HUMAN 26S PROTEASOME IN COMPLEX WITH OPROZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Haselbach, D., Schrader, J., Lambrecht, F., Henneberg, F., Chari, A., Stark, H.
Deposit date:2016-10-14
Release date:2017-07-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
5LN3
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THE HUMAN 26S PROTEASOME AT 6.8 ANG.
Descriptor:26S proteasome non-ATPase regulatory subunit 2, Proteasome subunit beta type-6, Proteasome subunit beta type-7, ...
Authors:Schweitzer, A., Beck, F., Sakata, E., Unverdorben, P.
Deposit date:2016-08-03
Release date:2017-03-22
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol. Cell Proteomics, 16, 2017
5L4K
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THE HUMAN 26S PROTEASOME LID
Descriptor:26S proteasome non-ATPase regulatory subunit 4, 26S proteasome non-ATPase regulatory subunit 14, 26S proteasome non-ATPase regulatory subunit 8, ...
Authors:Schweitzer, A., Aufderheide, A., Rudack, T., Beck, F.
Deposit date:2016-05-25
Release date:2016-09-07
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IXF
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SOLUTION STRUCTURE OF THE STAM2 SH3 WITH AMSH DERIVED PEPTIDE COMPLEX
Descriptor:Signal transducing adapter molecule 2, STAM-binding protein
Authors:Hologne, M., Cantrelle, F.X., Trivelli, X., Walker, O.
Deposit date:2016-03-23
Release date:2016-12-07
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin.
J.Mol.Biol., 428, 2016
5GJR
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AN ATOMIC STRUCTURE OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 4, 26S protease regulatory subunit 7, 26S protease regulatory subunit 10B, ...
Authors:Huang, X.L., Luan, B., Wu, J.P., Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2017-04-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
5GJQ
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STRUCTURE OF THE HUMAN 26S PROTEASOME BOUND TO USP14-UBAL
Descriptor:Proteasome subunit beta type-6, Proteasome subunit alpha type-6, Proteasome subunit beta type-7, ...
Authors:Huang, X.L., Luan, B., Wu, J.P., Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-08-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
2MUX
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SUMO2 NON-COVALENTLY INTERACTS WITH USP25 AND DOWNREGULATES ITS ACTIVITY
Descriptor:Ubiquitin carboxyl-terminal hydrolase 25
Authors:Shi, L., Zhang, N., Wen, Y.
Deposit date:2014-09-18
Release date:2016-04-20
Method:SOLUTION NMR
Cite:SUMO2 non-covalently interacts with USP25 and downregulates its activity
To be Published
2KLZ
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SOLUTION STRUCTURE OF THE TANDEM UIM DOMAIN OF ATAXIN-3 COMPLEXED WITH UBIQUITIN
Descriptor:Ataxin-3
Authors:Zhou, C., Song, A., Lin, D., Hu, H.
Deposit date:2009-07-12
Release date:2010-07-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin
To be Published
2KDF
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NMR STRUCTURE OF MINOR S5A (196-306):K48 LINKED DIUBIQUITIN SPECIES
Descriptor:26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Zhang, N., Wang, Q., Ehlinger, A., Randles, L., Lary, J.W., Kang, Y., Haririnia, A., Cole, J.L., Fushman, D., Walters, K.J.
Deposit date:2009-01-06
Release date:2009-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.
Mol.Cell, 35, 2009
2KDE
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NMR STRUCTURE OF MAJOR S5A (196-306):K48 LINKED DIUBIQUITIN SPECIES
Descriptor:26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Zhang, N., Wang, Q., Ehlinger, A., Randles, L., Lary, J.W., Kang, Y., Haririnia, A., Cole, J.L., Fushman, D., Walters, K.J.
Deposit date:2009-01-06
Release date:2009-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.
Mol.Cell, 35, 2009
1YX6
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SOLUTION STRUCTURE OF S5A UIM-2/UBIQUITIN COMPLEX
Descriptor:26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Wang, Q., Young, P., Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition
J.Mol.Biol., 348, 2005
1YX5
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SOLUTION STRUCTURE OF S5A UIM-1/UBIQUITIN COMPLEX
Descriptor:26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Wang, Q., Young, P., Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition
J.Mol.Biol., 348, 2005
1YX4
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STRUCTURE OF S5A BOUND TO MONOUBIQUITIN PROVIDES A MODEL FOR POLYUBIQUITIN RECOGNITION
Descriptor:26S proteasome non-ATPase regulatory subunit 4
Authors:Wang, Q., Young, P., Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
J.Mol.Biol., 348, 2005
1UEL
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SOLUTION STRUCTURE OF UBIQUITIN-LIKE DOMAIN OF HHR23B COMPLEXED WITH UBIQUITIN-INTERACTING MOTIF OF PROTEASOME SUBUNIT S5A
Descriptor:UV excision repair protein RAD23 homolog B, 26S proteasome non-ATPase regulatory subunit 4
Authors:Fujiwara, K., Tenno, T., Jee, J.G., Sugasawa, K., Ohki, I., Kojima, C., Tochio, H., Hiroaki, H., Hanaoka, H., Shirakawa, M., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-19
Release date:2004-02-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B
J.Biol.Chem., 279, 2004
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