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8SGZ
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BU of 8sgz by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGY
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BU of 8sgy by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (8.62 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGX
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BU of 8sgx by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (10.3 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8PN8
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BU of 8pn8 by Molmil
Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
Authors:Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J.
Deposit date:2023-06-30
Release date:2023-11-29
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
8PN7
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BU of 8pn7 by Molmil
Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
Authors:Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J.
Deposit date:2023-06-30
Release date:2023-11-29
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.03 Å)
Cite:Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
8HZ5
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BU of 8hz5 by Molmil
The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus
Descriptor: Biotin carboxylase
Authors:Shen, J, Wu, W, Xu, X.
Deposit date:2023-01-08
Release date:2024-01-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus
To be published
8HZ4
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BU of 8hz4 by Molmil
The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate
Descriptor: Biotin carboxylase
Authors:Shen, J, Wu, W, Xu, X.
Deposit date:2023-01-08
Release date:2024-01-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate
To be published
8HWL
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BU of 8hwl by Molmil
Human Pyruvate Carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
Authors:Liu, D.S, Su, J.Y.
Deposit date:2022-12-30
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (5.63 Å)
Cite:Human Pyruvate Carboxylase
To Be Published
8GK8
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BU of 8gk8 by Molmil
R21A Staphylococcus aureus pyruvate carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ...
Authors:Laseke, A.J, St.Maurice, M.
Deposit date:2023-03-17
Release date:2023-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase.
Biochemistry, 62, 2023
8FXI
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BU of 8fxi by Molmil
Cryo-EM structure of Stanieria sp. CphA2 in complex with ADPCP and 4x(beta-Asp-Arg)
Descriptor: 1-[(4-aminopyrimidin-5-yl)amino]-2,5-anhydro-1-deoxy-6-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl]-D-allitol, 4x(beta-Asp-Arg), MAGNESIUM ION, ...
Authors:Markus, L.M, Sharon, I, Strauss, M, Schmeing, T.M.
Deposit date:2023-01-24
Release date:2023-06-14
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure and function of a hexameric cyanophycin synthetase 2.
Protein Sci., 32, 2023
8FXH
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BU of 8fxh by Molmil
Cryo-EM structure of Stanieria sp. CphA2
Descriptor: RimK domain-containing protein ATP-grasp
Authors:Markus, L.M, Sharon, I, Strauss, M, Schmeing, T.M.
Deposit date:2023-01-24
Release date:2023-06-14
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure and function of a hexameric cyanophycin synthetase 2.
Protein Sci., 32, 2023
8F41
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BU of 8f41 by Molmil
3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ...
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-10
Release date:2023-01-11
Last modified:2023-01-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
8F3D
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BU of 8f3d by Molmil
3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-09
Release date:2023-01-11
Last modified:2023-01-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
7ZZ8
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BU of 7zz8 by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ6
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BU of 7zz6 by Molmil
Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-12-28
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ5
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BU of 7zz5 by Molmil
Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, BICARBONATE ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ4
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BU of 7zz4 by Molmil
Cryo-EM structure of "BC closed" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ3
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BU of 7zz3 by Molmil
Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ2
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BU of 7zz2 by Molmil
Cryo-EM structure of "CT pyr" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ1
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BU of 7zz1 by Molmil
Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: BIOTIN, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ0
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BU of 7zz0 by Molmil
Cryo-EM structure of "CT empty" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYZ
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BU of 7zyz by Molmil
Cryo-EM structure of "CT oxa" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MANGANESE (II) ION, OXALOACETATE ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYY
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BU of 7zyy by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.12 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7YBU
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BU of 7ybu by Molmil
Human propionyl-coenzyme A carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase alpha chain, mitochondrial, ...
Authors:Su, J.Y, Liu, D.S.
Deposit date:2022-06-29
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Human propionyl-coenzyme A carboxylase
To Be Published
7WTE
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BU of 7wte by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022

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PDB entries from 2024-03-27

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