4MV4
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH AMPPCP AND MG2
Descriptor:Biotin carboxylase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, 1,2-ETHANEDIOL, ...
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
4MV3
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH AMPPCP AND BICARBONATE
Descriptor:Biotin carboxylase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, 1,2-ETHANEDIOL, ...
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
5H80
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BIOTIN CARBOXYLASE DOMAIN OF SINGLE-CHAIN BACTERIAL CARBOXYLASE
Descriptor:Carboxylase, 1,2-ETHANEDIOL
Authors:Hagmann, A., Hunkeler, M., Stuttfeld, E., Maier, T.
Deposit date:2015-12-23
Release date:2016-07-20
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans.
Structure, 24, 2016
4MV7
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FORM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH PHOSPHONOFORMATE
Descriptor:Biotin carboxylase, PHOSPHONOFORMIC ACID, 1,2-ETHANEDIOL
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
2W70
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE AMINO-THIAZOLE-PYRIMIDINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
4MV6
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH PHOSPHONOACETAMIDE
Descriptor:Biotin carboxylase, 1,2-ETHANEDIOL, PHOSPHONOACETAMIDE
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
1W96
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL-COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH SORAPHEN A
Descriptor:ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A
Authors:Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L.
Deposit date:2004-10-06
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
2W6P
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH 5-METHYL-6-PHENYL-QUINAZOLINE-2,4-DIAMINE
Descriptor:ACETYL-COA CARBOXYLASE, 5-methyl-6-phenylquinazoline-2,4-diamine
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6N
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE, 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
1DV1
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STRUCTURE OF BIOTIN CARBOXYLASE (APO)
Descriptor:BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Thoden, J.B., Blanchard, C.Z., Holden, H.M., Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
2W6Z
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE 3-(3-METHYL-BUT-2-ENYL)-3H-PURIN-6-YLAMINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
3G8D
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CRYSTAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT, E296A MUTANT, OF ACETYL-COA CARBOXYLASE FROM ESCHERICHIA COLI
Descriptor:Biotin carboxylase, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chou, C.Y., Yu, L.P., Tong, L.
Deposit date:2009-02-12
Release date:2009-03-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism.
J.Biol.Chem., 284, 2009
3OUZ
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE-ADP COMPLEX FROM CAMPYLOBACTER JEJUNI
Descriptor:Biotin carboxylase, GLYCEROL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Maltseva, N., Kim, Y., Makowska-Grzyska, M., Mulligan, R., Papazisi, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-15
Release date:2010-10-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni
TO BE PUBLISHED
3RV3
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CRYSTAL STRUCTURE OF E.COLI BIOTIN CARBOXYLASE IN COMPLEX WITH TWO ADP AND ONE MG ION
Descriptor:Biotin carboxylase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Chou, C.Y., Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
4MV1
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH ADP AND PHOSPHATE
Descriptor:Biotin carboxylase, PHOSPHATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
5MLK
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BIOTIN DEPENDENT CARBOXYLASE ACCA3 DIMER FROM MYCOBACTERIUM TUBERCULOSIS (RV3285)
Descriptor:Acetyl-COA carboxylase
Authors:Bennett, M.D., Hogbom, M.
Deposit date:2016-12-07
Release date:2017-03-08
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (1.939 Å)
Cite:Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis.
FEBS Open Bio, 7, 2017
3RV4
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CRYSTAL STRUCTURE OF E.COLI BIOTIN CARBOXYLASE R16E MUTANT IN COMPLEX WITH MG-ADP AND BICARBONATE
Descriptor:Biotin carboxylase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chou, C.Y., Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
4MV9
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH BICARBONATE
Descriptor:Biotin carboxylase, 1,2-ETHANEDIOL, BICARBONATE ION
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R.J., Waldrop, G.L.
Deposit date:2013-09-23
Release date:2015-01-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
4RZQ
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STRUCTURAL ANALYSIS OF SUBSTRATE, REACTION INTERMEDIATE AND PRODUCT BINDING IN HAEMOPHILUS INFLUENZAE BIOTIN CARBOXYLASE
Descriptor:Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate, ADENOSINE-5'-DIPHOSPHATE
Authors:Broussard, T.C., Pakhomova, S., Neau, D.B., Champion, T.S., Bonnot, R., Waldrop, G.L.
Deposit date:2014-12-23
Release date:2015-06-10
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
2W71
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE IMIDAZOLE-PYRIMIDINE INHIBITOR
Descriptor:BIOTIN CARBOXYLASE, CHLORIDE ION, 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
3RUP
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CRYSTAL STRUCTURE OF E.COLI BIOTIN CARBOXYLASE IN COMPLEX WITH TWO ADP AND TWO CA IONS
Descriptor:Biotin carboxylase, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Chou, C.Y., Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
2QF7
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CRYSTAL STRUCTURE OF A COMPLETE MULTIFUNCTIONAL PYRUVATE CARBOXYLASE FROM RHIZOBIUM ETLI
Descriptor:Pyruvate carboxylase protein, MAGNESIUM ION, ZINC ION, ...
Authors:St Maurice, M., Surinya, K.H., Rayment, I.
Deposit date:2007-06-27
Release date:2007-09-04
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
2W6M
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE, (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
3G8C
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE IN COMPLEX WITH BIOTIN, BICARBONATE, ADP AND MG ION
Descriptor:Biotin carboxylase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chou, C.Y., Yu, L.P., Tong, L.
Deposit date:2009-02-12
Release date:2009-03-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism.
J.Biol.Chem., 284, 2009
2J9G
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMPPNP AND ADP
Descriptor:BIOTIN CARBOXYLASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
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