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5CMT	Fic protein from Neisseria meningitidis (NmFic) mutant E156R Y183F in dimeric form Descriptor: Adenosine monophosphate-protein transferase NmFic, CHLORIDE ION, GLYCEROL Authors: Stanger, F.V, Schirmer, T. Deposit date: 2015-07-17 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (0.99 Å) Cite: Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
5CKL	Fic protein from Neisseria meningitidis (NmFic) mutant E156R in dimeric form Descriptor: Adenosine monophosphate-protein transferase NmFic, CHLORIDE ION, GLYCEROL Authors: Stanger, F.V, Schirmer, T. Deposit date: 2015-07-15 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (0.99 Å) Cite: Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
3SHG	VBHT Fic protein from BARTONELLA SCHOENBUCHENSIS in complex with VBHA antitoxin Descriptor: L(+)-TARTARIC ACID, VbhA, VbhT Authors: Goepfert, A, Schirmer, T. Deposit date: 2011-06-16 Release date: 2012-01-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482, 2012
4N67	Crystal Structure of the N-terminal Fic Domain of a Putative Cell Filamentation protein (VirB-translocated Bep effector protein) with bound ADP from Bartonella quintana Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative cell filamentation protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-10-11 Release date: 2014-09-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
5EU0	FIC domain of Bep1 from Bartonella rochalimae in complex with BiaA Descriptor: Bartonella effector protein (Bep) substrate of VirB T4SS, SULFATE ION, antitoxin 1 Authors: Goepfert, A. Deposit date: 2015-11-18 Release date: 2017-03-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Molecular basis for Rho-family GTPase discrimination by a bacterial virulence factor to be published
3EQX	CRYSTAL STRUCTURE OF A FIC FAMILY PROTEIN (SO_4266) FROM SHEWANELLA ONEIDENSIS AT 1.6 A RESOLUTION Descriptor: FIC DOMAIN CONTAINING TRANSCRIPTIONAL REGULATOR, TRIETHYLENE GLYCOL Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-10-01 Release date: 2008-10-14 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution. Proteins, 75, 2009
3ZCN	Fic protein from SHEWANELLA ONEIDENSIS in complex with ATP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE SOFIC, ADENOSINE-5'-TRIPHOSPHATE Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-11-21 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
7B7Z	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 1) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Endoplasmic reticulum chaperone BiP, ... Authors: Perera, L.A, Ron, D. Deposit date: 2020-12-12 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
4WGJ	Crystal Structure of BepC protein (VirB-translocated Bartonella effector protein) with bound AMPPNP from Bartonella tribocorum Descriptor: 1,2-ETHANEDIOL, BepC protein, GLYCINE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-09-18 Release date: 2015-10-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
3SE5	Fic protein from NEISSERIA MENINGITIDIS mutant delta8 in complex with AMPPNP Descriptor: Cell filamentation protein Fic-related protein, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... Authors: Goepfert, A, Stanger, F, Schirmer, T. Deposit date: 2011-06-10 Release date: 2012-01-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482, 2012
3DD7	Structure of DocH66Y in complex with the C-terminal domain of Phd Descriptor: BROMIDE ION, Death on curing protein, Prevent host death protein Authors: Garcia-Pino, A, Loris, R. Deposit date: 2008-06-05 Release date: 2008-09-16 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation J.Biol.Chem., 283, 2008
3LET	Crystal Structure of Fic domain containing AMPylator, VopS Descriptor: Adenosine monophosphate-protein transferase vopS Authors: Luong, P.H, Kinch, L.N, Brautigam, C.A, Grishin, N.V, Tomchick, D.R, Orth, K. Deposit date: 2010-01-15 Release date: 2010-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation To be Published
3N3U	Crystal Structure of IbpAFic2 Descriptor: Adenosine monophosphate-protein transferase ibpA, SULFATE ION, ZINC ION Authors: Xiao, J. Deposit date: 2010-05-20 Release date: 2010-07-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.846 Å) Cite: Structural basis of Fic-mediated adenylylation. Nat.Struct.Mol.Biol., 17, 2010
4M16	Crystal Structure of the N-terminal Fic Domain of Bartonella effector protein (Bep); substrate of VirB T4SS (VirB-translocated Bep effector protein) from Bartonella sp. AR 15-3 Descriptor: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-08-02 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
7B80	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 2) Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Perera, L.A, Ron, D. Deposit date: 2020-12-12 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
4NPS	Crystal Structure of Bep1 protein (VirB-translocated Bartonella effector protein) from Bartonella clarridgeiae Descriptor: ACETATE ION, Bartonella effector protein (Bep) substrate of VirB T4SS Authors: Dranow, D.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-11-22 Release date: 2014-10-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
3ZCB	VbhT Fic protein from Bartonella schoenbuchensis in complex with VbhA antitoxin mutant E24G and ATP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE VBHT, ADENOSINE-5'-TRIPHOSPHATE, ANTITOXIN VBHA, ... Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-11-19 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
8CIL	Crystal structure of Coxiella burnetii Fic protein 2 Descriptor: Fic family protein Authors: Hoepfner, D, Itzen, A, Pogenberg, V. Deposit date: 2023-02-10 Release date: 2023-11-15 Method: X-RAY DIFFRACTION (1.98 Å) Cite: The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3. Commun Biol, 6, 2023
3ZLM	Fic protein from Neisseria meningitidis mutant E186G in complex with AMPPNP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE NMFIC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Goepfert, A, Schirmer, T. Deposit date: 2013-02-01 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
4LU4	Crystal Structure of the N-terminal Fic Domain of a Putative Cell Filamentation protein (VirB-translocated Bep effector protein) from Bartonella quintana Descriptor: BROMIDE ION, CHLORIDE ION, IODIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-07-24 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
5JFF	E. coli EcFicT mutant G55R in complex with EcFicA Descriptor: CHLORIDE ION, Probable adenosine monophosphate-protein transferase fic, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... Authors: Stanger, F.V, Schirmer, T. Deposit date: 2016-04-19 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. Plos One, 11, 2016
3ZC7	VbhT Fic protein from Bartonella schoenbuchensis in complex with VbhA antitoxin and ATP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE VBHT, ADENOSINE-5'-TRIPHOSPHATE, ANTITOXIN VBHA Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-11-19 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
3ZEC	Fic protein from SHEWANELLA ONEIDENSIS (E73G mutant) in complex with AMPPNP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE SOFIC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-12-04 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
3S6A	Fic protein from NEISSERIA MENINGITIDIS in complex with AMPPNP Descriptor: Cell filamentation protein Fic-related protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Stanger, F, Goepfert, A, Schirmer, T. Deposit date: 2011-05-25 Release date: 2012-01-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482, 2012
2G03	Structure of a putative cell filamentation protein from Neisseria meningitidis. Descriptor: ACETIC ACID, ISOPROPYL ALCOHOL, hypothetical protein NMA0004 Authors: Cuff, M.E, Bigelow, L, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2006-02-10 Release date: 2006-03-21 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of a putative cell filamentation protein from Neisseria meningitidis. To be Published

 

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