PDB: 59 resultsInfo pagesStatus searchChemie searchBIRD

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4WGJ	Crystal Structure of BepC protein (VirB-translocated Bartonella effector protein) with bound AMPPNP from Bartonella tribocorum Descriptor: 1,2-ETHANEDIOL, BepC protein, GLYCINE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-09-18 Release date: 2015-10-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
5EU0	FIC domain of Bep1 from Bartonella rochalimae in complex with BiaA Descriptor: Bartonella effector protein (Bep) substrate of VirB T4SS, SULFATE ION, antitoxin 1 Authors: Goepfert, A. Deposit date: 2015-11-18 Release date: 2017-03-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Molecular basis for Rho-family GTPase discrimination by a bacterial virulence factor to be published
7XUX	Crystal structure of a FIC domain containnig protein Descriptor: Fido domain-containing protein Authors: Zhen, X, Ouyang, S. Deposit date: 2022-05-20 Release date: 2022-12-21 Last modified: 2023-01-11 Method: X-RAY DIFFRACTION (2.78 Å) Cite: A secreted effector with a dual role as a toxin and as a transcriptional factor. Nat Commun, 13, 2022
2F6S	Structure of cell filamentation protein (fic) from Helicobacter pylori Descriptor: PHOSPHATE ION, ZINC ION, cell filamentation protein, ... Authors: Cuff, M.E, Xu, X, Zheng, H, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2005-11-29 Release date: 2006-01-10 Last modified: 2022-12-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of cell filamentation protein (fic) from Helicobacter pylori To be Published
2G03	Structure of a putative cell filamentation protein from Neisseria meningitidis. Descriptor: ACETIC ACID, ISOPROPYL ALCOHOL, hypothetical protein NMA0004 Authors: Cuff, M.E, Bigelow, L, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2006-02-10 Release date: 2006-03-21 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of a putative cell filamentation protein from Neisseria meningitidis. To be Published
3N3U	Crystal Structure of IbpAFic2 Descriptor: Adenosine monophosphate-protein transferase ibpA, SULFATE ION, ZINC ION Authors: Xiao, J. Deposit date: 2010-05-20 Release date: 2010-07-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.846 Å) Cite: Structural basis of Fic-mediated adenylylation. Nat.Struct.Mol.Biol., 17, 2010
7CB8	Structure of a FIC-domain protein from Mycobacterium marinum in complex with CDP Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CYTIDINE-5'-DIPHOSPHATE, ... Authors: Kumar, S, Singh, A, Penmatsa, A, Surolia, A. Deposit date: 2020-06-11 Release date: 2021-08-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of of a FIC-domain protein from Mycobacterium marinum To Be Published
3S6A	Fic protein from NEISSERIA MENINGITIDIS in complex with AMPPNP Descriptor: Cell filamentation protein Fic-related protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Stanger, F, Goepfert, A, Schirmer, T. Deposit date: 2011-05-25 Release date: 2012-01-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482, 2012
4XI8	Crystal Structure of the FIC domain of Bep5 protein (VirB-translocated Bartonella effector protein) from Bartonella clarridgeiae Descriptor: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-01-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
3CUC	CRYSTAL STRUCTURE OF A FIC DOMAIN CONTAINING SIGNALING PROTEIN (BT_2513) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.71 A RESOLUTION Descriptor: Protein of unknown function with a Fic domain Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-04-16 Release date: 2008-04-29 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Crystal structure of Protein of Unknown Function with a Fic Domain (NP_811426.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.71 A resolution To be published
5JJ7	Fic-1 (aa134 - 508 E274G) from C. elegans Descriptor: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION Authors: Cruz, V.E, Schwartz, T.U. Deposit date: 2016-04-22 Release date: 2016-06-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.749 Å) Cite: Fic-1 (aa134 - 508 E274G) from C. elegans To be published
3DD7	Structure of DocH66Y in complex with the C-terminal domain of Phd Descriptor: BROMIDE ION, Death on curing protein, Prevent host death protein Authors: Garcia-Pino, A, Loris, R. Deposit date: 2008-06-05 Release date: 2008-09-16 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation J.Biol.Chem., 283, 2008
3DD9	Structure of DocH66Y dimer Descriptor: Death on curing protein Authors: Garcia-Pino, A, Loris, R. Deposit date: 2008-06-05 Release date: 2009-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.45 Å) Cite: The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding J. Biol. Chem., 289, 2014
5JJ6	Fic-1 (aa134 - 508) from C. elegans Descriptor: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION Authors: Cruz, V.E, Schwartz, T.U. Deposit date: 2016-04-22 Release date: 2016-06-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.907 Å) Cite: Fic-1 dimer To be published
5CMT	Fic protein from Neisseria meningitidis (NmFic) mutant E156R Y183F in dimeric form Descriptor: Adenosine monophosphate-protein transferase NmFic, CHLORIDE ION, GLYCEROL Authors: Stanger, F.V, Schirmer, T. Deposit date: 2015-07-17 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (0.99 Å) Cite: Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
5CGL	Fic protein from Neisseria meningitidis (NmFic) mutant E102R in dimeric form Descriptor: Adenosine monophosphate-protein transferase NmFic, DI(HYDROXYETHYL)ETHER Authors: Stanger, F.V, Schirmer, T. Deposit date: 2015-07-09 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
5CKL	Fic protein from Neisseria meningitidis (NmFic) mutant E156R in dimeric form Descriptor: Adenosine monophosphate-protein transferase NmFic, CHLORIDE ION, GLYCEROL Authors: Stanger, F.V, Schirmer, T. Deposit date: 2015-07-15 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (0.99 Å) Cite: Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
4M16	Crystal Structure of the N-terminal Fic Domain of Bartonella effector protein (Bep); substrate of VirB T4SS (VirB-translocated Bep effector protein) from Bartonella sp. AR 15-3 Descriptor: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-08-02 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4LU4	Crystal Structure of the N-terminal Fic Domain of a Putative Cell Filamentation protein (VirB-translocated Bep effector protein) from Bartonella quintana Descriptor: BROMIDE ION, CHLORIDE ION, IODIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-07-24 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4N67	Crystal Structure of the N-terminal Fic Domain of a Putative Cell Filamentation protein (VirB-translocated Bep effector protein) with bound ADP from Bartonella quintana Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative cell filamentation protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-10-11 Release date: 2014-09-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4PY3	Crystal Structure of the N-terminal FIC domain of Bep8 protein (VirB-translocated Bartonella effector protein) from Bartonella sp. 1-1C Descriptor: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-03-25 Release date: 2015-06-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
6I7J	Crystal structure of monomeric FICD mutant L258D Descriptor: Adenosine monophosphate-protein transferase FICD, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... Authors: Perera, L.A, Yan, Y, Read, R.J, Ron, D. Deposit date: 2018-11-16 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.65 Å) Cite: An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. Embo J., 38, 2019
6I7K	Crystal structure of monomeric FICD mutant L258D complexed with MgATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ETHANOL, ... Authors: Perera, L.A, Yan, Y, Read, R.J, Ron, D. Deposit date: 2018-11-16 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.54 Å) Cite: An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. Embo J., 38, 2019
6I7H	Crystal structure of dimeric FICD mutant K256S Descriptor: Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION Authors: Perera, L.A, Yan, Y, Read, R.J, Ron, D. Deposit date: 2018-11-16 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.25 Å) Cite: An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. Embo J., 38, 2019
6I7I	Crystal structure of dimeric FICD mutant K256A complexed with MgATP Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ... Authors: Perera, L.A, Yan, Y, Read, R.J, Ron, D. Deposit date: 2018-11-16 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.33 Å) Cite: An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. Embo J., 38, 2019

 

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