1Q8D
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THE CRYSTAL STRUCTURE OF GDNF FAMILY CO-RECEPTOR ALPHA 1 DOMAIN 3
Descriptor:GDNF family receptor alpha 1, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Leppanen, V.M., Bespalov, M.M., Runeberg-Roos, P., Puurand, U., Merits, A., Saarma, M., Goldman, A.
Deposit date:2003-08-21
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.
Embo J., 23, 2004
2GH0
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GROWTH FACTOR/RECEPTOR COMPLEX
Descriptor:artemin, GDNF family receptor alpha-3, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, X.Q.
Deposit date:2006-03-24
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
Structure, 14, 2006
2V5E
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THE STRUCTURE OF THE GDNF:CORECEPTOR COMPLEX: INSIGHTS INTO RET SIGNALLING AND HEPARIN BINDING.
Descriptor:GDNF FAMILY RECEPTOR ALPHA-1, GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR, SUCROSE OCTASULFATE, ...
Authors:Parkash, V., Leppanen, V.-M., Virtanen, H., Jurvansuu, J.-M., Bespalov, M.M., Sidorova, Y.A., Runeberg-Roos, P., Saarma, M., Goldman, A.
Deposit date:2008-10-03
Release date:2008-10-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Structure of the Glial Cell Line-Derived Neurotrophic Factor-Coreceptor Complex: Insights Into Ret Signaling and Heparin Binding.
J.Biol.Chem., 283, 2008
3FUB
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CRYSTAL STRUCTURE OF GDNF-GFRALPHA1 COMPLEX
Descriptor:GDNF family receptor alpha-1, Glial cell line-derived neurotrophic factor, 1,2-ETHANEDIOL, ...
Authors:Parkash, V., Goldman, A.
Deposit date:2009-01-14
Release date:2009-06-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Comparison of GFL-GFRalpha complexes: further evidence relating GFL bend angle to RET signalling
Acta Crystallogr.,Sect.F, 65, 2009
4UX8
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RET RECOGNITION OF GDNF-GFRALPHA1 LIGAND BY A COMPOSITE BINDING SITE PROMOTES MEMBRANE-PROXIMAL SELF-ASSOCIATION
Descriptor:PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET, GDNF FAMILY RECEPTOR ALPHA-1, GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR, ...
Authors:Goodman, K., Kjaer, S., Beuron, F., Knowles, P., Nawrotek, A., Burns, E., Purkiss, A., George, R., Santoro, M., Morris, E.P., McDonald, N.Q.
Deposit date:2014-08-19
Release date:2014-10-01
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (24 Å)
Cite:Ret Recognition of Gdnf-Gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association.
Cell Rep., 8, 2014
5MR4
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LIGAND-RECEPTOR COMPLEX.
Descriptor:Neurturin, GDNF family receptor alpha-2, DI(HYDROXYETHYL)ETHER, ...
Authors:Sandmark, J., Oster, L., Aagaard, A., Roth, R.G., Dahl, G.
Deposit date:2016-12-21
Release date:2018-01-17
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
J. Biol. Chem., 293, 2018
5MR5
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LIGAND-RECEPTOR COMPLEX.
Descriptor:Neurturin, GDNF family receptor alpha-2, SULFATE ION, ...
Authors:Sandmark, J., Oster, L., Aagaard, A., Roth, R., Dahl, G.
Deposit date:2016-12-21
Release date:2018-01-17
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
J. Biol. Chem., 293, 2018
5VZ4
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RECEPTOR-GROWTH FACTOR CRYSTAL STRUCTURE AT 2.20 ANGSTROM RESOLUTION
Descriptor:Growth/differentiation factor 15, GDNF family receptor alpha-like, BROMIDE ION, ...
Authors:Lakshminarasimhan, D., White, A., Suto, R.K.
Deposit date:2017-05-26
Release date:2017-09-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Nature, 550, 2017
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