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1EK9
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2.1A X-RAY STRUCTURE OF TOLC: AN INTEGRAL OUTER MEMBRANE PROTEIN AND EFFLUX PUMP COMPONENT FROM ESCHERICHIA COLI
Descriptor: OUTER MEMBRANE PROTEIN TOLC
Authors:Koronakis, V, Sharff, A.J, Koronakis, E, Luisi, B, Hughes, C.
Deposit date:2000-03-07
Release date:2000-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export.
Nature, 405, 2000
3D5K
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Crystal structure of the OprM channel in a non-symmetrical space group
Descriptor: CHLORIDE ION, Outer membrane protein oprM, SODIUM ION
Authors:Phan, G, Broutin, I, Ducruix, A.
Deposit date:2008-05-16
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel.
Structure, 18, 2010
5IUY
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Structural insights of the outer-membrane channel OprN
Descriptor: CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ...
Authors:Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I.
Deposit date:2016-03-18
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
3PIK
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BU of 3pik by Molmil
Outer membrane protein CusC
Descriptor: Cation efflux system protein cusC, SULFATE ION, UNKNOWN LIGAND
Authors:van den Berg, B.
Deposit date:2010-11-06
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Escherichia coli CusC, the Outer Membrane Component of a Heavy Metal Efflux Pump.
Plos One, 6, 2011
5NSW
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BU of 5nsw by Molmil
Xenon for tunnelling analysis of the efflux pump component OprN.
Descriptor: Multidrug efflux outer membrane protein OprN, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Phan, G, Prange, T, Enguene Ntsogo, Y.V, Garnier, C, Ducruix, A, Broutin, I.
Deposit date:2017-04-27
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
4Y1K
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PALMITOYLATED OPRM OUTER MEMBRANE FACTOR
Descriptor: Outer membrane protein OprM, PALMITIC ACID
Authors:Monlezun, L, Phan, G, Broutin, I.
Deposit date:2015-02-07
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:New OprM structure highlighting the nature of the N-terminal anchor.
Front Microbiol, 6, 2015
6WXI
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BU of 6wxi by Molmil
Colicin E1 fragment in nanodisc-embedded TolC
Descriptor: Outer membrane protein TolC
Authors:Kaelber, J.T, Budiardjo, S.J, Firlar, E, Ikujuni, A.P, Slusky, J.S.G.
Deposit date:2020-05-10
Release date:2021-05-12
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Colicin E1 opens its hinge to plug TolC.
Elife, 11, 2022
6WXH
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BU of 6wxh by Molmil
Colicin E1 fragment in nanodisc-embedded TolC
Descriptor: Colicin-E1, Outer membrane protein TolC
Authors:Kaelber, J.T, Budiardjo, S.J, Firlar, E, Case, D.A, Ikujuni, A.P, Slusky, J.S.G.
Deposit date:2020-05-10
Release date:2021-05-12
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Colicin E1 opens its hinge to plug TolC.
Elife, 11, 2022
6ZRE
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BU of 6zre by Molmil
Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
Descriptor: Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ...
Authors:Ntsogo Enguene, Y.V, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I.
Deposit date:2020-07-13
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa.
To Be Published
7AKZ
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Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
Descriptor: Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside
Authors:Ntsogo Enguene, V.Y, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I.
Deposit date:2020-10-02
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
To Be Published
7NG8
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BU of 7ng8 by Molmil
Trimeric efflux pump Klebsiella TolC in complex with KlebC
Descriptor: Klebicin C activity, Outer membrane channel protein
Authors:Webby, M.N, Housden, N.G, Kleanthous, C.
Deposit date:2021-02-08
Release date:2021-06-30
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Toxin import through the antibiotic efflux channel TolC.
Nat Commun, 12, 2021
7NG9
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BU of 7ng9 by Molmil
Trimeric efflux pump Klebsiella TolC
Descriptor: Outer membrane channel protein
Authors:Webby, M.N, Housden, N.G, Kleanthous, C.
Deposit date:2021-02-08
Release date:2021-06-30
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Toxin import through the antibiotic efflux channel TolC.
Nat Commun, 12, 2021
5AZP
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BU of 5azp by Molmil
Crystal structure of a membrane protein from Pseudomonas aeruginosa
Descriptor: (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, ACETATE ION, FORMIC ACID, ...
Authors:Yonehara, R, Yamashita, E, Nakagawa, A.
Deposit date:2015-10-21
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa.
Proteins, 84, 2016
4K7K
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BU of 4k7k by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
Descriptor: Cation efflux system protein CusC
Authors:Su, C.-C, Lei, H.-T.
Deposit date:2013-04-17
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
4K7R
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BU of 4k7r by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
Descriptor: (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, Cation efflux system protein CusC
Authors:Su, C.-C, Lei, H.-T, Bolla, J.R, Yu, E.W.
Deposit date:2013-04-17
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
4K34
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BU of 4k34 by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
Descriptor: Cation efflux system protein CusC
Authors:Su, C.-C.
Deposit date:2013-04-10
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
5AZO
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BU of 5azo by Molmil
Crystal structure of a membrane protein from Pseudomonas aeruginosa
Descriptor: Multidrug efflux outer membrane protein OprN
Authors:Yonehara, R, Yamashita, E, Nakagawa, A.
Deposit date:2015-10-21
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa.
Proteins, 84, 2016
5BUN
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BU of 5bun by Molmil
Crystal structure of an antigenic outer membrane protein ST50 from Salmonella Typhi
Descriptor: Outer membrane protein, octyl beta-D-glucopyranoside
Authors:Yoshimura, M, Chuankhayan, P, Lin, C.C, Chen, N.C, Yang, M.C, Fun, H.K.
Deposit date:2015-06-04
Release date:2015-12-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism.
Sci Rep, 5, 2015
5AZS
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BU of 5azs by Molmil
Crystal structure of a membrane protein from Pseudomonas aeruginosa
Descriptor: Outer membrane protein OprJ
Authors:Yonehara, R, Yamashita, E, Nakagawa, A.
Deposit date:2015-10-21
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa.
Proteins, 84, 2016
1TQQ
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BU of 1tqq by Molmil
Structure of TolC in complex with hexamminecobalt
Descriptor: COBALT HEXAMMINE(III), Outer membrane protein tolC
Authors:Higgins, M.K, Eswaran, J, Edwards, P.C, Schertler, G.F, Hughes, C, Koronakis, V.
Deposit date:2004-06-18
Release date:2004-07-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug effllux protein TolC
J.Mol.Biol., 342, 2004
6U94
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BU of 6u94 by Molmil
Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344
Descriptor: GLYCEROL, RND efflux system, outer membrane lipoprotein, ...
Authors:Horanyi, P.S, Fox III, D, Abendroth, J, Lorimer, D, Edwards, T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-09-06
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344
To Be Published
4MT4
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BU of 4mt4 by Molmil
Crystal structure of the Campylobacter jejuni CmeC outer membrane channel
Descriptor: (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CmeC, ...
Authors:Su, C.-C, Yu, E.W.
Deposit date:2013-09-19
Release date:2014-09-24
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.373 Å)
Cite:Crystal structure of the Campylobacter jejuni CmeC outer membrane channel.
Protein Sci., 23, 2014
4MT0
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BU of 4mt0 by Molmil
Crystal Structure of the Open State of the Neisseria gonorrhoeae MtrE Outer Membrane Channel
Descriptor: MtrE protein, SULFATE ION
Authors:Su, C.-C, Bolla, J.R, Yu, E.W.
Deposit date:2013-09-18
Release date:2014-08-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.292 Å)
Cite:Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel.
Plos One, 9, 2014
1WP1
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BU of 1wp1 by Molmil
Crystal structure of the drug-discharge outer membrane protein, OprM
Descriptor: Outer membrane protein oprM
Authors:Akama, H, Kanemaki, M, Yoshimura, M, Tsukihara, T, Kashiwagi, T, Narita, S, Nakagawa, A, Nakae, T.
Deposit date:2004-08-28
Release date:2004-11-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: dual modes of membrane anchoring and occluded cavity end
J.Biol.Chem., 279, 2004
1YC9
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BU of 1yc9 by Molmil
The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 resolution
Descriptor: MERCURY (II) ION, multidrug resistance protein, octyl beta-D-glucopyranoside
Authors:Federici, L, Du, D, Walas, F, Matsumura, H, Fernandez-Recio, J, McKeegan, K.S, Borges-Walmsley, M.I, Luisi, B.F, Walmsley, A.R.
Deposit date:2004-12-22
Release date:2005-03-01
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the outer membrane protein VCEC from the bacterial pathogen vibrio cholerae at 1.8 A resolution
J.Biol.Chem., 280, 2005

 

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