6B9G
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HUMAN ATL1 GTPASE DOMAIN BOUND TO GDP
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:O'Donnell, J.P., Sondermann, H.
Deposit date:2017-10-10
Release date:2017-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
6B9F
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HUMAN ATL1 MUTANT - F151S BOUND TO GDPALF4-
Descriptor:Atlastin-1, GLYCEROL, MAGNESIUM ION, ...
Authors:O'Donnell, J.P., Sondermann, H.
Deposit date:2017-10-10
Release date:2017-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
6B9E
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HUMAN ATL1 MUTANT - R77A / F151S BOUND TO GDP
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:O'Donnell, J.P., Sondermann, H.
Deposit date:2017-10-10
Release date:2017-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
6B9D
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HUMAN ATL1 MUTANT - R77A BOUND TO GDP
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:O'Donnell, J.P., Sondermann, H.
Deposit date:2017-10-10
Release date:2017-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
5VGR
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HUMAN ATLASTIN-3, GDP-BOUND
Descriptor:Atlastin-3, GUANOSINE-5'-DIPHOSPHATE
Authors:O'Donnell, J.P., Sondermann, H.
Deposit date:2017-04-11
Release date:2017-05-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin.
Structure, 25, 2017
4IDQ
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HUMAN ATLASTIN-1 1-446, N440T, GDPALF4-
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, ...
Authors:Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
Deposit date:2012-12-12
Release date:2013-01-09
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
4IDP
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HUMAN ATLASTIN-1 1-446, N440T, GPPNHP
Descriptor:Atlastin-1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
Deposit date:2012-12-12
Release date:2013-01-09
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.587 Å)
Cite:Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
4IDO
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HUMAN ATLASTIN-1 1-446, C-HIS6, GDPALF4-
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, ...
Authors:Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
Deposit date:2012-12-12
Release date:2013-01-09
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
4IDN
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HUMAN ATLASTIN-1 1-446, C-HIS6, GPPNHP
Descriptor:Atlastin-1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
Deposit date:2012-12-12
Release date:2013-01-09
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
3X1D
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CRYSTAL STRUCTURE OF ATLASTIN FROM DROSOPHILA MELANOGASTER
Descriptor:Atlastin, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Liu, X.
Deposit date:2014-11-14
Release date:2015-10-28
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Comparison of human and Drosophila atlastin GTPases
Protein Cell, 6, 2015
3QOF
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CRYSTAL STRUCTURE OF THE CYTOSOLIC DOMAIN OF HUMAN ATLASTIN-1 IN COMPLEX WITH GDP, ORTHORHOMBIC FORM
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Liu, X.
Deposit date:2011-02-09
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QNU
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CRYSTAL STRUCTURE OF THE CYTOSOLIC DOMAIN OF HUMAN ATLASTIN-1 IN COMPLEX WITH GDP, HEXAGONAL FORM
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Liu, X.
Deposit date:2011-02-09
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q5E
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CRYSTAL STRUCTURE OF HUMAN ATLASTIN-1 (RESIDUES 1-447) BOUND TO GDP, CRYSTAL FORM 2
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Byrnes, L.J., Sondermann, H.
Deposit date:2010-12-28
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.013 Å)
Cite:Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q5D
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CRYSTAL STRUCTURE OF HUMAN ATLASTIN-1 (RESIDUES 1-447) BOUND TO GDP, CRYSTAL FORM 1
Descriptor:Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Byrnes, L.J., Sondermann, H.
Deposit date:2010-12-28
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A.
Proc.Natl.Acad.Sci.USA, 108, 2011
2D4H
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP
Descriptor:Interferon-induced guanylate-binding protein 1, GUANOSINE-5'-MONOPHOSPHATE
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2BC9
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH NON-HYDROLYSABLE GTP ANALOGUE GPPNHP
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B92
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GDP/ALF3
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B8W
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF4
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ...
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
1F5N
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HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.
Descriptor:INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Prakash, B., Renault, L., Praefcke, G.J.K., Herrmann, C., Wittinghofer, A.
Deposit date:2000-06-15
Release date:2000-09-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
1DG3
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STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM
Descriptor:PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
Authors:Prakash, B., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:1999-11-23
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
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