Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8E1D
DownloadVisualize
BU of 8e1d by Molmil
NMR-derived ensemble of the TAZ2 domain of p300 bound to the microphthalmia-associated transcription factor
Descriptor: Histone acetyltransferase p300, Microphthalmia-associated transcription factor, ZINC ION
Authors:Langelaan, D.N, Branch, M.
Deposit date:2022-08-10
Release date:2023-06-21
Last modified:2023-07-12
Method:SOLUTION NMR
Cite:Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
3T92
DownloadVisualize
BU of 3t92 by Molmil
Crystal structure of the Taz2:C/EBPepsilon-TAD chimera protein
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, ACETONE, HISTONE ACETYLTRANSFERASE P300 TAZ2-CCAAT/ENHANCER-BINDING PROTEIN EPSILON, ...
Authors:Bhaumik, P, Maria, M.
Deposit date:2011-08-02
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
3IO2
DownloadVisualize
BU of 3io2 by Molmil
Crystal structure of the Taz2 domain of p300
Descriptor: Histone acetyltransferase p300, SULFATE ION, ZINC ION
Authors:Miller, M, Dauter, Z, Wlodawer, A.
Deposit date:2009-08-13
Release date:2009-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Taz2 domain of p300: insights into ligand binding.
Acta Crystallogr.,Sect.D, 65, 2009
1F81
DownloadVisualize
BU of 1f81 by Molmil
SOLUTION STRUCTURE OF THE TAZ2 DOMAIN OF THE TRANSCRIPTIONAL ADAPTOR PROTEIN CBP
Descriptor: CREB-BINDING PROTEIN, ZINC ION
Authors:De Guzman, R.N, Liu, H.L, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
Deposit date:2000-06-28
Release date:2000-10-18
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
J.Mol.Biol., 303, 2000
1P4Q
DownloadVisualize
BU of 1p4q by Molmil
Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain
Descriptor: Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION
Authors:Freedman, S.J, Sun, Z.-Y.J, Kung, A.L, France, D.S, Wagner, G, Eck, M.J.
Deposit date:2003-04-23
Release date:2003-07-01
Last modified:2017-02-01
Method:SOLUTION NMR
Cite:Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
Nat.Struct.Biol., 10, 2003
6FGS
DownloadVisualize
BU of 6fgs by Molmil
Solution structure of p300Taz2-p73TA1
Descriptor: Histone acetyltransferase p300,Tumor protein p73, ZINC ION
Authors:Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V.
Deposit date:2018-01-11
Release date:2018-05-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.
Structure, 26, 2018
6FGN
DownloadVisualize
BU of 6fgn by Molmil
Solution Structure of p300Taz2-p63TA
Descriptor: Histone acetyltransferase p300,Tumor protein 63, ZINC ION
Authors:Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V.
Deposit date:2018-01-11
Release date:2018-05-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.
Structure, 26, 2018
7XFG
DownloadVisualize
BU of 7xfg by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
Descriptor: Histone acetyltransferase p300, NUT family member 1, ZINC ION
Authors:Yu, D, Zeng, L, Zhou, M.-M.
Deposit date:2022-04-01
Release date:2023-04-12
Method:SOLUTION NMR
Cite:Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XEZ
DownloadVisualize
BU of 7xez by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
Descriptor: Histone acetyltransferase p300,NUT family member 1, ZINC ION
Authors:Yu, D, Zeng, L, Zhou, M.-M.
Deposit date:2022-03-31
Release date:2023-04-12
Method:SOLUTION NMR
Cite:Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
1R8U
DownloadVisualize
BU of 1r8u by Molmil
NMR structure of CBP TAZ1/CITED2 complex
Descriptor: CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION
Authors:De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
Deposit date:2003-10-28
Release date:2004-03-23
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279, 2004
1LIQ
DownloadVisualize
BU of 1liq by Molmil
Non-native Solution Structure of a fragment of the CH1 domain of CBP
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Matthews, J.M, Kwan, A.H.Y, Newton, A, Gell, D.A, Crossley, M, Mackay, J.P.
Deposit date:2002-04-18
Release date:2002-05-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A New Zinc Binding Fold Underlines the Versatility of Zinc Binding Modules in Protein Evolution
Structure, 10, 2002
1U2N
DownloadVisualize
BU of 1u2n by Molmil
Structure CBP TAZ1 Domain
Descriptor: CREB binding protein, ZINC ION
Authors:De Guzman, R.N, Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2004-07-19
Release date:2005-04-26
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
Biochemistry, 44, 2005
1WO3
DownloadVisualize
BU of 1wo3 by Molmil
Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WO6
DownloadVisualize
BU of 1wo6 by Molmil
Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WO4
DownloadVisualize
BU of 1wo4 by Molmil
Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WO5
DownloadVisualize
BU of 1wo5 by Molmil
Solution structure of Designed Functional Finger 2 (DFF2): Designed mutant based on non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WO7
DownloadVisualize
BU of 1wo7 by Molmil
Solution structure of Designed Functional Finger 7 (DFF7): Designed mutant based on non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
2KJE
DownloadVisualize
BU of 2kje by Molmil
NMR structure of CBP TAZ2 and adenoviral E1A complex
Descriptor: CREB-binding protein, Early E1A 32 kDa protein, ZINC ION
Authors:Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E.
Deposit date:2009-05-27
Release date:2009-09-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LWW
DownloadVisualize
BU of 2lww by Molmil
NMR structure of RelA-TAD/CBP-TAZ1 complex
Descriptor: CREB-binding protein, Nuclear transcription factor RelA, ZINC ION
Authors:Mukherjee, S.P, Ghosh, G, Wright, P.E.
Deposit date:2012-08-07
Release date:2013-09-11
Last modified:2013-09-18
Method:SOLUTION NMR
Cite:Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-kappa B-Driven Transcription.
Plos Biol., 11, 2013
2MH0
DownloadVisualize
BU of 2mh0 by Molmil
Solution NMR structure of the p300 Taz2:ETAD1 complex
Descriptor: Histone acetyltransferase p300, Transcription factor E2-alpha
Authors:Langelaan, D.N, Smith, S.P, Chitayat, S.
Deposit date:2013-11-12
Release date:2014-11-12
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.
J.Biol.Chem., 295, 2020
2MZD
DownloadVisualize
BU of 2mzd by Molmil
Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex
Descriptor: Cellular tumor antigen p53, Histone acetyltransferase p300
Authors:Miller Jenkins, L.M, Feng, H, Durell, S.R, Tagad, H.D, Mazur, S.J, Tropea, J.E, Bai, Y, Appella, E.
Deposit date:2015-02-11
Release date:2015-03-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex.
Biochemistry, 54, 2015
7LVS
DownloadVisualize
BU of 7lvs by Molmil
The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide
Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION
Authors:Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2021-02-26
Release date:2021-07-28
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The molecular basis of allostery in a facilitated dissociation process.
Structure, 29, 2021
7QGS
DownloadVisualize
BU of 7qgs by Molmil
Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid)
Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION
Authors:Hegedus, Z, Wilson, A.J, Edwards, T.A.
Deposit date:2021-12-10
Release date:2022-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Understanding p300-transcription factor interactions using sequence variation and hybridization.
Rsc Chem Biol, 3, 2022
5HP0
DownloadVisualize
BU of 5hp0 by Molmil
Solution Structure of TAZ2-p53AD2
Descriptor: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
Authors:Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2016-01-19
Release date:2016-03-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HPD
DownloadVisualize
BU of 5hpd by Molmil
Solution Structure of TAZ2-p53TAD
Descriptor: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
Authors:Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016

 

12>

218500

PDB entries from 2024-04-17

PDB statisticsPDBj update infoContact PDBjnumon