PDB: 33 resultsInfo pagesStatus searchChemie searchBIRD

---

6LCJ	TtGalA, alpha-galactosidase from Thermus thermopilus in apo form Descriptor: Alpha-galactosidase Authors: Chen, S.C, Hsu, C.H. Deposit date: 2019-11-19 Release date: 2020-07-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of alpha-Galactosidase fromThermus thermophilus: Insight into Hexamer Assembly and Substrate Specificity. J.Agric.Food Chem., 68, 2020
6LCL	TtGalA, alpha-galactosidase from Thermus thermophilus in complex with stachyose Descriptor: Alpha-galactosidase, alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose Authors: Chen, S.C, Hsu, C.H. Deposit date: 2019-11-19 Release date: 2020-09-30 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal Structure of alpha-Galactosidase from Thermus thermophilus : Insight into Hexamer Assembly and Substrate Specificity. J.Agric.Food Chem., 68, 2020
6LCK	TtGalA, alpha-galactosidase from Thermus thermophilus in complex with p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG) Descriptor: 4-nitrophenyl alpha-D-galactopyranoside, Alpha-galactosidase Authors: Chen, S.C, Hsu, C.H. Deposit date: 2019-11-19 Release date: 2020-07-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Crystal Structure of alpha-Galactosidase fromThermus thermophilus: Insight into Hexamer Assembly and Substrate Specificity. J.Agric.Food Chem., 68, 2020
6PHV	SpAga galactose product complex structure Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-galactosidase, ... Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6PHY	SpAga D472N structure in complex alpha 1,3 galactobiose Descriptor: 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6PI0	AgaD472N-Linear Blood group B type 2 trisaccharide complex structure Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Alpha-galactosidase, ... Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6PHW	SpAga D472N structure in complex with melibiose Descriptor: 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6PHU	SpAga wild type apo structure Descriptor: 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6PHX	SpAga D472N structure in complex with raffinose Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Alpha-galactosidase, ... Authors: Pluvinage, B, Boraston, A.B. Deposit date: 2019-06-25 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
6JHP	Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-galactosidase Authors: Liu, Y, Huang, P, Ma, J, Jiang, Z. Deposit date: 2019-02-18 Release date: 2020-05-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.559 Å) Cite: Crystal structure and phylogenetic analysis of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila To be published
6GX8	Alpha-galactosidase from Thermotoga maritima in complex with hydrolysed cyclohexene-based carbasugar mimic of galactose Descriptor: (1~{S},2~{S},3~{S},4~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol, Alpha-galactosidase, GLYCEROL, ... Authors: Gloster, T.M, Oehler, V. Deposit date: 2018-06-26 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
6GWG	Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose covalently linked to the nucleophile Descriptor: (1~{S},2~{S},3~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol, Alpha-galactosidase, GLYCEROL, ... Authors: Gloster, T.M, Oehler, V. Deposit date: 2018-06-24 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
6GWF	Alpha-galactosidase mutant D387A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 2,4-dinitro leaving group Descriptor: (1~{S},2~{S},5~{S},6~{R})-5-(2,4-dinitrophenoxy)-6-fluoranyl-3-(hydroxymethyl)cyclohex-3-ene-1,2-diol, Alpha-galactosidase, MAGNESIUM ION, ... Authors: Gloster, T.M, Oehler, V. Deposit date: 2018-06-24 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
6GVD	Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose Descriptor: (1~{S},2~{S},3~{S},4~{S})-5-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Alpha-galactosidase, MAGNESIUM ION, ... Authors: Gloster, T.M, Pengelly, R.J. Deposit date: 2018-06-20 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
6GTA	Alpha-galactosidase mutant D378A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 3,5 difluorophenyl leaving group Descriptor: (1~{R},2~{S},3~{S},6~{S})-6-[3,5-bis(fluoranyl)phenoxy]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol, Alpha-galactosidase, MAGNESIUM ION, ... Authors: Gloster, T.M, Pengelly, R.J. Deposit date: 2018-06-17 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
5M12	Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with intact cyclopropyl-carbasugar. Descriptor: (1~{R},2~{S},3~{S},4~{R},5~{S},6~{S})-5-[3,5-bis(fluoranyl)phenoxy]-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4-triol, Alpha-galactosidase, MAGNESIUM ION, ... Authors: Pengelly, R, Gloster, T. Deposit date: 2016-10-07 Release date: 2016-11-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
5M16	Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with a hydrolysed cyclopropyl carbasugar. Descriptor: (1~{R},2~{S},3~{S},4~{S},5~{S},6~{S})-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4,5-tetrol, Alpha-galactosidase, MAGNESIUM ION, ... Authors: Pengelly, R, Gloster, T. Deposit date: 2016-10-07 Release date: 2016-11-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
5M1I	Structure of GH36 alpha-galactosidase from Thermotoga maritima in a covalent complex with a cyclopropyl carbasugar. Descriptor: (1~{R},2~{S},3~{S},4~{S},6~{R})-4-fluoranyl-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3-diol, 1,2-ETHANEDIOL, Alpha-galactosidase, ... Authors: Pengelly, R, Gloster, T. Deposit date: 2016-10-07 Release date: 2016-11-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
5M0X	Structure of apo structure of GH36 alpha-galactosidase from Thermotoga maritima Descriptor: Alpha-galactosidase, MAGNESIUM ION, SULFATE ION Authors: Pengelly, R, Gloster, T. Deposit date: 2016-10-06 Release date: 2016-11-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
4OGZ	Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution Descriptor: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Putative alpha-galactosidase/melibiase, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2014-01-16 Release date: 2014-02-05 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution To be published
4FNT	Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose Descriptor: Alpha-galactosidase AgaA, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose Authors: Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. Deposit date: 2012-06-20 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
4FNP	Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus Descriptor: Alpha-galactosidase AgaA, SULFATE ION Authors: Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. Deposit date: 2012-06-20 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.803 Å) Cite: The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
4FNQ	Crystal structure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus Descriptor: 1,2-ETHANEDIOL, Alpha-galactosidase AgaB Authors: Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. Deposit date: 2012-06-20 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
4FNU	Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose Descriptor: Alpha-galactosidase AgaA, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose-(1-6)-alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose Authors: Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. Deposit date: 2012-06-20 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.6 Å) Cite: The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
4FNR	Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus Descriptor: Alpha-galactosidase AgaA Authors: Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. Deposit date: 2012-06-20 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012

 

12>