1ZY9
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CRYSTAL STRUCTURE OF ALPHA-GALACTOSIDASE (EC 3.2.1.22) (MELIBIASE) (TM1192) FROM THERMOTOGA MARITIMA AT 2.34 A RESOLUTION
Descriptor:alpha-galactosidase, 1,2-ETHANEDIOL, GLYCEROL
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-06-09
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of alpha-galactosidase (ec 3.2.1.22) (melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution
to be published
2XN0
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STRUCTURE OF ALPHA-GALACTOSIDASE FROM LACTOBACILLUS ACIDOPHILUS NCFM, PTCL4 DERIVATIVE
Descriptor:ALPHA-GALACTOSIDASE, PLATINUM (II) ION, GLYCEROL
Authors:Fredslund, F., Abou Hachem, M., Larsen, R.J., Sorensen, P.G., Lo Leggio, L., Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
2XN1
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STRUCTURE OF ALPHA-GALACTOSIDASE FROM LACTOBACILLUS ACIDOPHILUS NCFM WITH TRIS
Descriptor:ALPHA-GALACTOSIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL
Authors:Fredslund, F., Abou Hachem, M., Larsen, R.J., Sorensen, P.G., Lo Leggio, L., Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
2XN2
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STRUCTURE OF ALPHA-GALACTOSIDASE FROM LACTOBACILLUS ACIDOPHILUS NCFM WITH GALACTOSE
Descriptor:ALPHA-GALACTOSIDASE, ALPHA D-GALACTOSE, IMIDAZOLE, ...
Authors:Fredslund, F., Abou Hachem, M., Larsen, R.J., Sorensen, P.G., Lo Leggio, L., Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
2YFN
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GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK
Descriptor:ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Sulzenbacher, G., Bruel, L., Tison-Cervera, M., Pujol, A., Nicoletti, C., Perrier, J., Galinier, A., Ropartz, D., Fons, M., Pompeo, F., Giardina, T.
Deposit date:2011-04-07
Release date:2011-09-28
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities
J.Biol.Chem., 286, 2011
2YFO
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GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK, IN COMPLEX WITH GALACTOSE
Descriptor:ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, TRIETHYLENE GLYCOL, ...
Authors:Sulzenbacher, G., Bruel, L., Tison-Cervera, M., Pujol, A., Nicoletti, C., Perrier, J., Galinier, A., Ropartz, D., Fons, M., Pompeo, F., Giardina, T.
Deposit date:2011-04-07
Release date:2011-09-28
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities
J.Biol.Chem., 286, 2011
3MI6
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CRYSTAL STRUCTURE OF THE ALPHA-GALACTOSIDASE FROM LACTOBACILLUS BREVIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LBR11.
Descriptor:Alpha-galactosidase
Authors:Vorobiev, S., Chen, Y., Seetharaman, J., Belote, R., Sahdev, S., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-09
Release date:2010-04-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Crystal structure of the alpha-galactosidase from Lactobacillus brevis.
To be Published
4FNP
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA A355E FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Alpha-galactosidase AgaA, SULFATE ION
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4FNQ
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAB FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Alpha-galactosidase AgaB, 1,2-ETHANEDIOL
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4FNR
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Alpha-galactosidase AgaA
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4FNS
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA A355E FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH 1-DEOXYGALACTONOJIRIMYCIN
Descriptor:Alpha-galactosidase AgaA, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, SULFATE ION, ...
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4FNT
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA A355E D548N FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH RAFFINOSE
Descriptor:Alpha-galactosidase AgaA, raffinose
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4FNU
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CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA A355E D478A FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH STACHYOSE
Descriptor:Alpha-galactosidase AgaA, ALPHA D-GALACTOSE, ALPHA-D-GLUCOSE, ...
Authors:Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
Deposit date:2012-06-20
Release date:2012-10-03
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
4OGZ
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CRYSTAL STRUCTURE OF A PUTATIVE ALPHA-GALACTOSIDASE/MELIBIASE (BF4189) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 2.00 A RESOLUTION
Descriptor:Putative alpha-galactosidase/melibiase, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2014-01-16
Release date:2014-02-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution
To be published
5M0X
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STRUCTURE OF APO STRUCTURE OF GH36 ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA
Descriptor:Alpha-galactosidase, MAGNESIUM ION, SULFATE ION
Authors:Pengelly, R., Gloster, T.
Deposit date:2016-10-06
Release date:2016-11-09
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
5M12
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STRUCTURE OF GH36 ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH INTACT CYCLOPROPYL-CARBASUGAR.
Descriptor:Alpha-galactosidase, SULFATE ION, MAGNESIUM ION, ...
Authors:Pengelly, R., Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
5M16
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STRUCTURE OF GH36 ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH A HYDROLYSED CYCLOPROPYL CARBASUGAR.
Descriptor:Alpha-galactosidase, SULFATE ION, MAGNESIUM ION, ...
Authors:Pengelly, R., Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
5M1I
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STRUCTURE OF GH36 ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN A COVALENT COMPLEX WITH A CYCLOPROPYL CARBASUGAR.
Descriptor:Alpha-galactosidase, SULFATE ION, (1~{R},2~{S},3~{S},4~{S},6~{R})-4-fluoranyl-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3-diol, ...
Authors:Pengelly, R., Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
6GTA
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ALPHA-GALACTOSIDASE MUTANT D378A FROM THERMOTOGA MARITIMA IN COMPLEX WITH INTACT CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE WITH 3,5 DIFLUOROPHENYL LEAVING GROUP
Descriptor:Alpha-galactosidase, SULFATE ION, MAGNESIUM ION, ...
Authors:Gloster, T.M., Pengelly, R.J.
Deposit date:2018-06-17
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GVD
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ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE
Descriptor:Alpha-galactosidase, SULFATE ION, MAGNESIUM ION, ...
Authors:Gloster, T.M., Pengelly, R.J.
Deposit date:2018-06-20
Release date:2018-08-22
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GWF
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ALPHA-GALACTOSIDASE MUTANT D387A FROM THERMOTOGA MARITIMA IN COMPLEX WITH INTACT CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE WITH 2,4-DINITRO LEAVING GROUP
Descriptor:Alpha-galactosidase, SULFATE ION, (1~{S},2~{S},5~{S},6~{R})-5-(2,4-dinitrophenoxy)-6-fluoranyl-3-(hydroxymethyl)cyclohex-3-ene-1,2-diol, ...
Authors:Gloster, T.M., Oehler, V.
Deposit date:2018-06-24
Release date:2018-08-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GWG
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ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE COVALENTLY LINKED TO THE NUCLEOPHILE
Descriptor:Alpha-galactosidase, SULFATE ION, (1~{S},2~{S},3~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol, ...
Authors:Gloster, T.M., Oehler, V.
Deposit date:2018-06-24
Release date:2018-08-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GX8
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ALPHA-GALACTOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH HYDROLYSED CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE
Descriptor:Alpha-galactosidase, SULFATE ION, (1~{S},2~{S},3~{S},4~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol, ...
Authors:Gloster, T.M., Oehler, V.
Deposit date:2018-06-26
Release date:2018-08-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
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