3ZR5
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STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE
Descriptor:CALCIUM ION, GALACTOCEREBROSIDASE, N-ACETYL-D-GLUCOSAMINE
Authors:Deane, J.E., Graham, S.C., Kim, N.N., Stein, P.E., Mcnair, R., Cachon-Gonzalez, M.B., Cox, T.M., Read, R.J.
Deposit date:2011-06-14
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3ZR6
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STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE
Descriptor:BETA-D-GALACTOSE, BETA-D-MANNOSE, CALCIUM ION, ...
Authors:Deane, J.E., Graham, S.C., Kim, N.N., Stein, P.E., Mcnair, R., Cachon-Gonzalez, M.B., Cox, T.M., Read, R.J.
Deposit date:2011-06-14
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
4CCC
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STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX
Descriptor:1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
Deposit date:2013-10-21
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4CCD
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STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH D-GALACTAL: ENZYME- INTERMEDIATE COMPLEX
Descriptor:2-DEOXY-BETA-D-GALACTOSE, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
Deposit date:2013-10-21
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4CCE
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STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX
Descriptor:BETA-D-GALACTOSE, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
Deposit date:2013-10-21
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4UFH
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH ISO-GALACTO-FAGOMINE IGF
Descriptor:CALCIUM ION, D-galacto-isofagomine, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFI
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH AZA-GALACTO-FAGOMINE AGF
Descriptor:(3R,4S,5R)-3-(hydroxymethyl)-1,2-diazinane-4,5-diol, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFJ
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH ISO-GALACTO-FAGOMINE LACTAM IGL
Descriptor:(3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)piperidin-2-one, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFK
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH DIDEOXY-IMINO-LYXITOL DIL
Descriptor:CALCIUM ION, DIDEOXY-IMINO-LYXITOL, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFL
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH DEOXY-GALACTO-NOEUROSTEGINE DGN
Descriptor:CALCIUM ION, DEOXY-GALACTO-NOEUROSTEGINE, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFM
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MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH 1-DEOXY-GALACTO-NOJIRIMYCIN DGJ
Descriptor:(2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, CALCIUM ION, GALACTOCEREBROSIDASE, ...
Authors:Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Deposit date:2015-03-17
Release date:2015-04-01
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
5NXB
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MOUSE GALACTOCEREBROSIDASE IN COMPLEX WITH SAPOSIN A
Descriptor:BETA-D-MANNOSE, CALCIUM ION, Galactocerebrosidase, ...
Authors:Graham, S.C., Hill, C.H., Deane, J.E.
Deposit date:2017-05-09
Release date:2017-05-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The mechanism of sphingolipid processing revealed by a GALC-SapA complex structure
bioRxiv, 2017
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