2IRV
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CRYSTAL STRUCTURE OF GLPG, A RHOMBOID INTRAMEMBRANE SERINE PROTEASE
Descriptor:Protein glpG
Authors:Bibi, E., Fass, D., Ben-Shem, A.
Deposit date:2006-10-16
Release date:2006-10-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for intramembrane proteolysis by rhomboid serine proteases.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2NR9
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CRYSTAL STRUCTURE OF GLPG, RHOMBOID PEPTIDASE FROM HAEMOPHILUS INFLUENZAE
Descriptor:Protein glpG homolog (E.C.3.4.21.105)
Authors:Lemieux, M.J., Fischer, S.J., Cherney, M.M., Bateman, K.S., James, M.N.G.
Deposit date:2006-11-01
Release date:2006-11-14
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis.
Proc.Natl.Acad.Sci.USA, 104, 2007
3ODJ
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CRYSTAL STRUCTURE OF H. INFLUENZAE RHOMBOID GLPG WITH DISORDERED LOOP 4, HELIX 5 AND LOOP 5
Descriptor:Rhomboid protease glpG (E.C.3.4.21.105)
Authors:Brooks, C.L., Lazareno-Saez, C., Lamoureux, J.S., Mak, M.W., Lemieux, M.J.
Deposit date:2010-08-11
Release date:2011-02-23
Modification date:2011-03-30
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Insights into Substrate Gating in H. influenzae Rhomboid.
J.Mol.Biol., 407, 2011
4NJN
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CRYSTAL STRUCTURE OF E.COLI GLPG AT PH 4.5
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105)
Authors:Dickey, S.W., Baker, R.P., Cho, S., Urban, S.
Deposit date:2013-11-11
Release date:2013-12-25
Modification date:2014-01-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013
4NJP
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PROTEOLYSIS INSIDE THE MEMBRANE IS A RATE-GOVERNED REACTION NOT DRIVEN BY SUBSTRATE AFFINITY
Descriptor:Rhomboid protease GlpG
Authors:Dickey, S.W., Baker, R.P., Cho, S., Urban, S.
Deposit date:2013-11-11
Release date:2013-12-25
Modification date:2014-01-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013
5F5B
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STRUCTURE OF E.COLI GLPG COMPLEXED WITH PEPTIDIC INHIBITOR AC-VRMA-CHO
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105), peptidic derivative of Gurken
Authors:Urban, S., Cho, S., Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5D
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CRYSTAL STRUCTURES AND INHIBITION KINETICS REVEAL A TWO-STATE CATALYTIC MECHANISM WITH DRUG DESIGN IMPLICATIONS FOR RHOMBOID PROTEOLYSIS
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105)
Authors:Urban, S., Cho, S., Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5G
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STRUCTURE OF E.COLI GLPG Y205F MUTANT COMPLEXED WITH PEPTIDIC INHIBITOR AC-RMA-CHO IN THE DMPC/CHAPSO BICELLE
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105), ACE-ARG-MET-ALA
Authors:Urban, S., Cho, S., Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-04-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5J
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E.COLI GLPG Y205F MUTANT COMPLEXED WITH ALDEHYDE INHIBITOR IN DMPC/CHAPSO BICELLE
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105), peptidic derivative of Gurken
Authors:Urban, S., Cho, S., Dickey, S.
Deposit date:2015-12-04
Release date:2016-02-10
Modification date:2016-02-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5K
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E.COLI GLPG Y205F MUTANT COMPLEXED WITH ALDEHYDE INHIBITOR IN DMPC/CHAPSO BICELLE
Descriptor:Rhomboid protease GlpG (E.C.3.4.21.105), Peptidic derivative of Gurken
Authors:Urban, S., Cho, S., Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-10
Modification date:2016-02-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
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