1FMI
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE
Descriptor:CALCIUM ION, ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I, SULFATE ION
Authors:Vallee, F., Karaveg, K., Herscovics, A., Moremen, K.W., Howell, P.L.
Deposit date:2000-08-17
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO2
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Descriptor:1-DEOXYMANNOJIRIMYCIN, ALPHA1,2-MANNOSIDASE, CALCIUM ION, ...
Authors:Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO3
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE
Descriptor:ALPHA1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ...
Authors:Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1HCU
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ALPHA-1,2-MANNOSIDASE FROM TRICHODERMA REESEI
Descriptor:ALPHA-1,2-MANNOSIDASE, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE
Authors:Van Petegem, F., Contreras, H., Contreras, R., Van Beeumen, J.
Deposit date:2001-05-09
Release date:2001-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Trichoderma Reesei Alpha-1,2-Mannosidase: Structural Basis for the Cleavage of Four Consecutive Mannose Residues
J.Mol.Biol., 312, 2001
1KKT
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STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES
Descriptor:ALPHA-D-MANNOSE, CALCIUM ION, Mannosyl-oligosaccharide alpha-1,2-mannosidase, ...
Authors:Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.
Deposit date:2001-12-10
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1KRE
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STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES
Descriptor:1-DEOXYMANNOJIRIMYCIN, ALPHA-D-MANNOSE, CALCIUM ION, ...
Authors:Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.
Deposit date:2002-01-09
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1KRF
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STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES
Descriptor:ALPHA-D-MANNOSE, CALCIUM ION, KIFUNENSINE, ...
Authors:Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.
Deposit date:2002-01-09
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1NXC
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STRUCTURE OF MOUSE GOLGI ALPHA-1,2-MANNOSIDASE IA REVEALS THE MOLECULAR BASIS FOR SUBSTRATE SPECIFICITY AMONG CLASS I ENZYMES (FAMILY 47 GLYCOSIDASES)
Descriptor:ALPHA-D-MANNOSE, BETA-D-MANNOSE, CALCIUM ION, ...
Authors:Tempel, W., Liu, Z.-J., Karaveg, K., Rose, J., Moremen, K.W., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-02-10
Release date:2004-05-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases
J.Biol.Chem., 279, 2004
1X9D
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA-1,2-MANNOSIDASE IN COMPLEX WITH THIO-DISACCHARIDE SUBSTRATE ANALOGUE
Descriptor:1,4-BUTANEDIOL, CALCIUM ION, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
Authors:Karaveg, K., Tempel, W., Liu, Z.J., Siriwardena, A., Moremen, K.W., Wang, B.C.
Deposit date:2004-08-20
Release date:2005-02-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.
J.Biol.Chem., 280, 2005
2RI8
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PENICILLIUM CITRINUM ALPHA-1,2-MANNOSIDASE COMPLEX WITH GLYCEROL
Descriptor:ALPHA-D-MANNOSE, CALCIUM ION, GLYCEROL, ...
Authors:Lobsanov, Y.D., Yoshida, T., Desmet, T., Nerinckx, W., Yip, P., Claeyssens, M., Herscovics, A., Howell, P.L
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
2RI9
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PENICILLIUM CITRINUM ALPHA-1,2-MANNOSIDASE IN COMPLEX WITH A SUBSTRATE ANALOG
Descriptor:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ALPHA-D-MANNOSE, CALCIUM ION, ...
Authors:Lobsanov, Y.D., Yoshida, T., Desmet, T., Nerinckx, W., Yip, P., Claeyssens, M., Herscovics, A., Howell, P.L.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
4AYO
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STRUCTURE OF THE GH47 PROCESSING ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER STRAIN K31
Descriptor:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE, ...
Authors:Thompson, A.J., Dabin, J., Iglesias-Fernandez, J., Iglesias-Fernandez, A., Dinev, Z., Williams, S.J., Siriwardena, A., Moreland, C., Hu, T.C., Smith, D.K., Gilbert, H.J., Rovira, C., Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYP
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STRUCTURE OF THE GH47 PROCESSING ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER STRAIN K31 IN COMPLEX WITH THIOMANNOBIOSIDE
Descriptor:CALCIUM ION, MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE, ...
Authors:Thompson, A.J., Dabin, J., Iglesias-Fernandez, J., Iglesias-Fernandez, A., Dinev, Z., Williams, S.J., Siriwardena, A., Moreland, C., Hu, T.C., Smith, D.K., Gilbert, H.J., Rovira, C., Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYQ
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STRUCTURE OF THE GH47 PROCESSING ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER STRAIN K31 IN COMPLEX WITH MANNOIMIDAZOLE
Descriptor:(5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Thompson, A.J., Dabin, J., Iglesias-Fernandez, J., Iglesias-Fernandez, A., Dinev, Z., Williams, S.J., Siriwardena, A., Moreland, C., Hu, T.C., Smith, D.K., Gilbert, H.J., Rovira, C., Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYR
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STRUCTURE OF THE GH47 PROCESSING ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER STRAIN K31 IN COMPLEX WITH NOEUROMYCIN
Descriptor:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, ...
Authors:Thompson, A.J., Dabin, J., Iglesias-Fernandez, J., Iglesias-Fernandez, A., Dinev, Z., Williams, S.J., Siriwardena, A., Moreland, C., Hu, T.C., Smith, D.K., Gilbert, H.J., Rovira, C., Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
5KIJ
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CRYSTAL STRUCTURE OF THE CLASS I HUMAN ENDOPLASMIC RETICULUM 1,2-ALPHA-MANNOSIDASE AND MAN9GLCNAC2-PA COMPLEX
Descriptor:1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ALPHA-D-MANNOSE, ...
Authors:Karaveg, K., Xiang, Y., Moremen, K.W.
Deposit date:2016-06-16
Release date:2017-05-10
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KK7
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CRYSTAL STRUCTURE OF THE CLASS I HUMAN ENDOPLASMIC RETICULUM 1,2-ALPHA-MANNOSIDASE T688A MUTANT AND THIO-DISACCHARIDE SUBSTRATE ANALOG COMPLEX
Descriptor:1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, ...
Authors:Karaveg, K., Xiang, Y., Moremen, K.W.
Deposit date:2016-06-21
Release date:2017-05-10
Method:X-RAY DIFFRACTION (1.7324 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KKB
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STRUCTURE OF MOUSE GOLGI ALPHA-1,2-MANNOSIDASE IA AND MAN9GLCNAC2-PA COMPLEX
Descriptor:1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ALPHA-D-MANNOSE, ...
Authors:Xiang, Y., Moremen, K.W.
Deposit date:2016-06-21
Release date:2016-12-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5MEH
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CRYSTAL STRUCTURE OF ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER K31 STRAIN IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Descriptor:1-DEOXYMANNOJIRIMYCIN, ACETATE ION, CALCIUM ION, ...
Authors:Males, A., Davies, G.J.
Deposit date:2016-11-14
Release date:2016-12-21
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Conformational Behaviour of Azasugars Based on Mannuronic Acid.
Chembiochem, 18, 2017
5NE5
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CRYSTAL STRUCTURE OF FAMILY 47 ALPHA-1,2-MANNOSIDASE FROM CAULOBACTER K31 STRAIN IN COMPLEX WITH KIFUNENSINE
Descriptor:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, KIFUNENSINE, ...
Authors:Males, A., Davies, G.J.
Deposit date:2017-03-09
Release date:2017-03-29
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach.
Chembiochem, 18, 2017
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