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1EW4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI CYAY PROTEIN REVEALS A NOVEL FOLD FOR THE FRATAXIN FAMILY
Descriptor: CYAY PROTEIN
Authors:Suh, S.W, Cho, S, Lee, M.G, Yang, J.K, Lee, J.Y, Song, H.K.
Deposit date:2000-04-22
Release date:2000-08-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of Escherichia coli CyaY protein reveals a previously unidentified fold for the evolutionarily conserved frataxin family.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EKG
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MATURE HUMAN FRATAXIN
Descriptor: FRATAXIN
Authors:Dhe-Paganon, S, Shigeta, R, Chi, Y.I, Ristow, M, Shoelson, S.E.
Deposit date:2000-03-08
Release date:2000-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human frataxin.
J.Biol.Chem., 275, 2000
1LY7
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The solution structure of the the c-terminal domain of frataxin, the protein responsible for friedreich ataxia
Descriptor: frataxin
Authors:Musco, G, Stier, G, Kolmerer, B, Adinolfi, S, Martin, S, Frenkiel, T, Gibson, T, Pastore, A.
Deposit date:2002-06-07
Release date:2002-06-26
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin
Structure Fold.Des., 8, 2000
1SOY
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Solution structure of the bacterial frataxin orthologue, CyaY
Descriptor: CyaY protein
Authors:Nair, M, Adinolfi, S, Pastore, C, Kelly, G, Temussi, P, Pastore, A.
Deposit date:2004-03-16
Release date:2004-11-23
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of the Bacterial Frataxin Ortholog, CyaY; Mapping the Iron Binding Sites
Structure, 12, 2004
2GA5
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yeast frataxin
Descriptor: Frataxin homolog, mitochondrial
Authors:He, Y, Alam, S.L, Proteasa, S.V, Zhang, Y, Lesuisse, E, Dancis, A.
Deposit date:2006-03-07
Release date:2006-03-21
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Yeast Frataxin Solution Structure, Iron Binding and Ferrochelatase Interaction
Biochemistry, 43, 2004
2FQL
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Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae
Descriptor: Frataxin homolog, mitochondrial
Authors:Al-Karadaghi, S, Karlberg, T.
Deposit date:2006-01-18
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.
Structure, 14, 2006
2P1X
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Crystal structure analysis of the complex between CyaY and Eu(III)
Descriptor: EUROPIUM (III) ION, Protein cyaY
Authors:Sica, F, Franzese, M.
Deposit date:2007-03-06
Release date:2007-10-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein-a study of bacterial frataxin
Febs J., 274, 2007
2EFF
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BU of 2eff by Molmil
Crystal structure analysis of the complex between CyaY and Co(II)
Descriptor: COBALT (II) ION, Protein cyaY
Authors:Sica, F, Franzese, M.
Deposit date:2007-02-22
Release date:2007-10-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin
Febs J., 274, 2007
3S5D
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Crystal structure of human frataxin variant W155A
Descriptor: Frataxin, mitochondrial, SULFATE ION
Authors:Tsai, C.-L, Bridwell-Rabb, J, Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S5E
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Crystal structure of human frataxin variant W155R, one of the Friedreich's ataxia point mutations
Descriptor: Frataxin, mitochondrial, MAGNESIUM ION
Authors:Tsai, C.-L, Bridwell-Rabb, J, Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S5F
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Crystal structure of human frataxin variant W155F
Descriptor: Frataxin, mitochondrial, MAGNESIUM ION
Authors:Tsai, C.-L, Bridwell-Rabb, J, Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S4M
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BU of 3s4m by Molmil
Crystal structure of wild-type human frataxin
Descriptor: Frataxin, mitochondrial
Authors:Tsai, C.-L, Bridwell-Rabb, J, Barondeau, D.P.
Deposit date:2011-05-19
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3T3J
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1.70 A structure of Friedreich's ataxia frataxin variant N146K
Descriptor: Frataxin, mitochondrial
Authors:Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3L
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1.15 A structure of human frataxin variant Q153A
Descriptor: Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3X
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1.57 A structure of Friedreich's ataxia frataxin variant R165C
Descriptor: Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3K
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1.24 A Structure of Friedreich's ataxia frataxin variant Q148R
Descriptor: Frataxin, mitochondrial
Authors:Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3T
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1.38 A structure of human frataxin variant Q148G
Descriptor: Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3OEQ
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BU of 3oeq by Molmil
Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, with full length n-terminus
Descriptor: Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011
3OER
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BU of 3oer by Molmil
Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae, complexed with cobalt
Descriptor: COBALT (II) ION, Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011
4EC2
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BU of 4ec2 by Molmil
Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous
Descriptor: FE (II) ION, Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G, Rajan, S, Gakh, O, Isaya, G, Al-Karadaghi, S.
Deposit date:2012-03-26
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.
J.Biol.Chem., 288, 2013
4HS5
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Frataxin from Psychromonas ingrahamii as a model to study stability modulation within CyaY protein family
Descriptor: Protein CyaY
Authors:Roman, E.A, Cousido-siah, A, Mitschler, A, Podjarny, A, Santos, J.
Deposit date:2012-10-29
Release date:2013-03-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family
Biochim.Biophys.Acta, 1834, 2013
4JPD
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The structure of CyaY from Burkholderia cenocepacia
Descriptor: ACETATE ION, Protein CyaY, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-03-19
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of CyaY from Burkholderia cenocepacia
To be Published
4LK8
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Crystal structure of CyaY protein from Psychromonas ingrahamii in complex with Co(II)
Descriptor: COBALT (II) ION, Protein CyaY
Authors:Noguera, M.E, Roman, E.A, Cousido-Siah, A, Mitschler, A, Podjarny, A, Santos, J.
Deposit date:2013-07-07
Release date:2014-07-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:Structural characterization of metal binding to a cold-adapted frataxin
J.Biol.Inorg.Chem., 20, 2015
4LP1
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Crystal structure of CyaY protein from Psychromonas ingrahamii in complex with Eu(III)
Descriptor: EUROPIUM (III) ION, Protein CyaY
Authors:Noguera, M.E, Roman, E.A, Cousido-Siah, A, Mitschler, A, Podjarny, A, Santos, J.
Deposit date:2013-07-14
Release date:2014-07-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural characterization of metal binding to a cold-adapted frataxin
J.Biol.Inorg.Chem., 20, 2015
5T0V
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Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: the Sub-Complex Formed by the Iron Donor, Yfh1, and the Scaffold, Isu1
Descriptor: Frataxin homolog, mitochondrial, Iron sulfur cluster assembly protein 1
Authors:Ranatunga, W, Gakh, O, Galeano, B.K, Smith IV, D.Y, Soderberg, C.A, Al-Karadaghi, S, Thompson, J.R, Isaya, G.
Deposit date:2016-08-16
Release date:2016-08-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (17.5 Å)
Cite:Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: the Sub-Complex Formed by the Iron Donor, Yfh1, and the Scaffold, Isu1
J. Biol. Chem., 291, 2016

 

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