2B7O
  • Download 2b7o
  • View 2b7o
Molmil generated image of 2b7o
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, SULFATE ION, ...
Authors:Webby, C.J., Baker, H.M., Lott, J.S., Baker, E.N., Parker, E.J., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-10-05
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes
J.Mol.Biol., 354, 2005
2YPO
  • Download 2ypo
  • View 2ypo
Molmil generated image of 2ypo
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE WITH PHENYLALANINE BOUND IN ONLY ONE SITE
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE AROG, MANGANESE (II) ION, SULFATE ION, ...
Authors:Blackmore, N.J., Reichau, S., Jiao, W., Hutton, R.D., Baker, E.N., Jameson, G.B., Parker, E.J.
Deposit date:2012-10-31
Release date:2013-01-09
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis.
J.Mol.Biol., 425, 2013
2YPP
  • Download 2ypp
  • View 2ypp
Molmil generated image of 2ypp
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE IN COMPLEX WITH 3 TYROSINE MOLECULES
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE AROG, TYROSINE, MANGANESE (II) ION, ...
Authors:Blackmore, N.J., Reichau, S., Jiao, W., Hutton, R.D., Baker, E.N., Jameson, G.B., Parker, E.J.
Deposit date:2012-10-31
Release date:2013-01-09
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis.
J.Mol.Biol., 425, 2013
2YPQ
  • Download 2ypq
  • View 2ypq
Molmil generated image of 2ypq
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE WITH TRYPTOPHAN AND TYROSINE BOUND
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE AROG, TYROSINE, MANGANESE (II) ION, ...
Authors:Blackmore, N.J., Reichau, S., Jiao, W., Hutton, R.D., Baker, E.N., Jameson, G.B., Parker, E.J.
Deposit date:2012-10-31
Release date:2013-01-09
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis.
J.Mol.Biol., 425, 2013
3KGF
  • Download 3kgf
  • View 3kgf
Molmil generated image of 3kgf
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH PHENYLALANINE AND TRYPTOPHAN
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, PHENYLALANINE, TRYPTOPHAN, ...
Authors:Parker, E.J., Jameson, G.B., Jiao, W., Webby, C.J., Baker, E.N., Baker, H.M., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2009-10-29
Release date:2010-07-28
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3NUD
  • Download 3nud
  • View 3nud
Molmil generated image of 3nud
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH PHENYLALANINE
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, PHENYLALANINE, PHOSPHATE ION
Authors:Parker, E.J., Jameson, G.B., Jiao, W., Webby, C.J., Baker, E.N., Baker, H.M.
Deposit date:2010-07-06
Release date:2010-07-28
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3NUE
  • Download 3nue
  • View 3nue
Molmil generated image of 3nue
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH TRYPTOPHAN
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, TRYPTOPHAN, ...
Authors:Parker, E.J., Jameson, G.B., Jiao, W., Webby, C.J., Baker, E.N., Baker, H.M.
Deposit date:2010-07-06
Release date:2010-07-28
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3NV8
  • Download 3nv8
  • View 3nv8
Molmil generated image of 3nv8
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE IN COMPLEX WITH PHOSPHOENOL PYRUVATE AND MANGANESE (THESIT-FREE)
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, SULFATE ION, MANGANESE (II) ION, ...
Authors:Parker, E.J., Jameson, G.B., Jiao, W., Hutton, R.H., Webby, C.J., Baker, E.N., Baker, H.M.
Deposit date:2010-07-08
Release date:2010-07-28
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3PFP
  • Download 3pfp
  • View 3pfp
Molmil generated image of 3pfp
STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN ACTIVE SITE INHIBITOR
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, (2S)-2,7-bis(phosphonooxy)heptanoic acid, ...
Authors:Reichau, S., Jiao, W., Walker, S.R., Hutton, R.D., Parker, E.J., Baker, E.N.
Deposit date:2010-10-28
Release date:2011-03-16
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design
J.Biol.Chem., 286, 2011
3RZI
  • Download 3rzi
  • View 3rzi
Molmil generated image of 3rzi
THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COCRYSTALLIZED AND COMPLEXED WITH PHENYLALANINE AND TRYPTOPHAN
Descriptor:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, PHENYLALANINE, ...
Authors:Jiao, W., Jameson, G.B., Hutton, R.D., Parker, E.J.
Deposit date:2011-05-11
Release date:2012-01-25
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.
J.Mol.Biol., 415, 2012
5CKV
  • Download 5ckv
  • View 5ckv
Molmil generated image of 5ckv
DAHP SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS, FULLY INHIBITED BY TYROSINE, PHENYLALANINE, AND TRYPTOPHAN
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase AroG, CHLORIDE ION, SULFATE ION, ...
Authors:Munack, S., Krengel, U.
Deposit date:2015-07-15
Release date:2016-01-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.787 Å)
Cite:Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway.
J.Mol.Biol., 428, 2016
5E2L
  • Download 5e2l
  • View 5e2l
Molmil generated image of 5e2l
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH D-PHENYLALANINE
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ...
Authors:Reichau, S., Jiao, W., Parker, E.J.
Deposit date:2015-10-01
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5E40
  • Download 5e40
  • View 5e40
Molmil generated image of 5e40
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS WITH D-TYROSINE BOUND IN THE PHENYLALANINE BINDING SITE
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ...
Authors:Reichau, S., Jiao, W., Parker, E.J.
Deposit date:2015-10-05
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5E4N
  • Download 5e4n
  • View 5e4n
Molmil generated image of 5e4n
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS WITH D-TYROSINE BOUND IN THE TYROSINE AND PHENYLALANINE BINDING SITES
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, CHLORIDE ION, ...
Authors:Reichau, S., Jiao, W., Parker, E.J.
Deposit date:2015-10-06
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5E5G
  • Download 5e5g
  • View 5e5g
Molmil generated image of 5e5g
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE WITH D-TRYPTOPHAN BOUND IN THE TRYPTOPHAN AND PHENYLALANINE BINDING SITES
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ...
Authors:Reichau, S., Jiao, W., Parker, E.J.
Deposit date:2015-10-08
Release date:2016-06-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5E7Z
  • Download 5e7z
  • View 5e7z
Molmil generated image of 5e7z
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH D/L-TRYPTOPHAN AND D-PHENYLALANINE
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ...
Authors:Reichau, S., Jiao, W., Parker, E.J.
Deposit date:2015-10-13
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5EX4
  • Download 5ex4
  • View 5ex4
Molmil generated image of 5ex4
3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH TRYPTOPHAN IN ALL THREE ALLOSTERIC BINDING SITES
Descriptor:3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, MANGANESE (II) ION, TRYPTOPHAN, ...
Authors:Reichau, S., Jiao, W., Blackmore, N.J., Hutton, R.D., Parker, E.J.
Deposit date:2015-11-23
Release date:2015-12-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with tryptophan in all three allosteric binding sites
to be published
5HUC
  • Download 5huc
  • View 5huc
Molmil generated image of 5huc
DAHP SYNTHASE FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Burschowsky, D., Heim, J.B., Thorbjoernsrud, H.V., Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
5HUE
  • Download 5hue
  • View 5hue
Molmil generated image of 5hue
DAHP SYNTHASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH TRYPTOPHAN
Descriptor:3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Burschowsky, D., Heim, J.B., Thorbjoernsrud, H.V., Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
5UXM
  • Download 5uxm
  • View 5uxm
Molmil generated image of 5uxm
TYPE II DAH7PS FROM PSEUDOMONAS AERUGINOSA WITH TRP BOUND
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase, PHOSPHOENOLPYRUVATE, TRYPTOPHAN, ...
Authors:Sterritt, O.W., Jameson, G.B., Parker, E.J.
Deposit date:2017-02-23
Release date:2018-02-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A Pseudoisostructural Type II DAH7PS Enzyme from Pseudomonas aeruginosa: Alternative Evolutionary Strategies to Control Shikimate Pathway Flux.
Biochemistry, 57, 2018
5UXN
  • Download 5uxn
  • View 5uxn
Molmil generated image of 5uxn
TYPE II DAH7PS FROM PSEUDOMONAS AERUGINOSA WITH TYR BOUND
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase, PHOSPHATE ION, COBALT (II) ION, ...
Authors:Sterritt, O.W., Jameson, G.B., Parker, E.J.
Deposit date:2017-02-23
Release date:2018-02-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Pseudoisostructural Type II DAH7PS Enzyme from Pseudomonas aeruginosa: Alternative Evolutionary Strategies to Control Shikimate Pathway Flux.
Biochemistry, 57, 2018
5UXO
  • Download 5uxo
  • View 5uxo
Molmil generated image of 5uxo
TYPE II DAH7PS FROM PSEUDOMONAS AERUGINOSA
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase, COBALT (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Sterritt, O.W., Jameson, G.B., Parker, E.J.
Deposit date:2017-02-23
Release date:2018-02-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A Pseudoisostructural Type II DAH7PS Enzyme from Pseudomonas aeruginosa: Alternative Evolutionary Strategies to Control Shikimate Pathway Flux.
Biochemistry, 57, 2018
6BMC
  • Download 6bmc
  • View 6bmc
Molmil generated image of 6bmc
THE STRUCTURE OF A DIMERIC TYPE II DAH7PS ASSOCIATED WITH PYOCYANIN BIOSYNTHESIS IN PSEUDOMONAS AERUGINOSA
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase, PHOSPHOENOLPYRUVATE, COBALT (II) ION, ...
Authors:Sterritt, O.W., Jameson, G.B., Parker, E.J.
Deposit date:2017-11-14
Release date:2018-10-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The short-form type II DAH7PS fromPseudomonas aeruginosa, associated with phenazine biosynthesis, suggests reclassification of type II enzymes.
Biosci. Rep., 2018
2W19
  • Download 2w19
  • View 2w19
Molmil generated image of 2w19
NON-COVALENT COMPLEX BETWEEN DAHP SYNTHASE AND CHORISMATE MUTASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, CHORISMATE MUTASE, GLYCEROL, ...
Authors:Okvist, M., Sasso, S., Roderer, K., Gamper, M., Codoni, G., Krengel, U., Kast, P.
Deposit date:2008-10-16
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner.
Embo J., 28, 2009
2W1A
  • Download 2w1a
  • View 2w1a
Molmil generated image of 2w1a
NON-COVALENT COMPLEX BETWEEN DAHP SYNTHASE AND CHORISMATE MUTASE FROM MYCOBACTERIUM TUBERCULOSIS WITH BOUND TSA
Descriptor:3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, CHORISMATE MUTASE, MANGANESE (II) ION, ...
Authors:Okvist, M., Sasso, S., Roderer, K., Gamper, M., Codoni, G., Krengel, U., Kast, P.
Deposit date:2008-10-16
Release date:2009-07-07
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner.
Embo J., 28, 2009
<12>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2018 Protein Data Bank Japan