4LJX
  • Download 4ljx
  • View 4ljx
Molmil generated image of 4ljx
CRYSTAL STRUCTURE OF AN AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A (ARID3A) FROM HOMO SAPIENS AT 2.21 A RESOLUTION
Descriptor:AT-rich interactive domain-containing protein 3A
Authors:Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
Deposit date:2013-07-05
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of an AT-rich interactive domain-containing protein 3A (ARID3A) from Homo sapiens at 2.21 A resolution
To be published
1C20
  • Download 1c20
  • View 1c20
Molmil generated image of 1c20
SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN FROM THE DEAD RINGER PROTEIN
Descriptor:DEAD RINGER PROTEIN
Authors:Iwahara, J., Clubb, R.T.
Deposit date:1999-07-22
Release date:1999-11-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA binding domain from Dead ringer, a sequence-specific AT-rich interaction domain (ARID).
EMBO J., 18, 1999
1IG6
  • Download 1ig6
  • View 1ig6
Molmil generated image of 1ig6
HUMAN MRF-2 DOMAIN, NMR, 11 STRUCTURES
Descriptor:MODULATOR RECOGNITION FACTOR 2
Authors:Lin, D., Tsui, V., Case, D., Yuan, Y.C., Chen, Y.
Deposit date:2001-04-17
Release date:2001-04-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:HUMAN MRF-2 DOMAIN, NMR, 11 STRUCTURES
To be Published
1KKX
  • Download 1kkx
  • View 1kkx
Molmil generated image of 1kkx
SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF ADR6
Descriptor:Transcription regulatory protein ADR6
Authors:Tu, X., Wu, J., Xu, Y., Shi, Y.
Deposit date:2001-12-10
Release date:2002-07-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
1KN5
  • Download 1kn5
  • View 1kn5
Molmil generated image of 1kn5
SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE
Descriptor:Transcription regulatory protein ADR6
Authors:Tu, X., Wu, J., Xu, Y., Shi, Y.
Deposit date:2001-12-18
Release date:2002-07-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
1KQQ
  • Download 1kqq
  • View 1kqq
Molmil generated image of 1kqq
SOLUTION STRUCTURE OF THE DEAD RINGER ARID-DNA COMPLEX
Descriptor:5'-D(*CP*CP*TP*GP*TP*AP*TP*TP*GP*AP*TP*GP*TP*GP*G)-3', 5'-D(*CP*CP*AP*CP*AP*TP*CP*AP*AP*TP*AP*CP*AP*GP*G)-3', DEAD RINGER PROTEIN
Authors:Iwahara, J., Iwahara, M., Daughdrill, G.W., Ford, J., Clubb, R.T.
Deposit date:2002-01-07
Release date:2002-03-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.
EMBO J., 21, 2002
1RYU
  • Download 1ryu
  • View 1ryu
Molmil generated image of 1ryu
SOLUTION STRUCTURE OF THE SWI1 ARID
Descriptor:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1
Authors:Kim, S., Zhang, Z., Upchurch, S., Isern, N., Chen, Y.
Deposit date:2003-12-22
Release date:2004-05-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition.
J.Biol.Chem., 279, 2004
2CXY
  • Download 2cxy
  • View 2cxy
Molmil generated image of 2cxy
CRYSTAL STRUCTURE OF THE HBAF250B AT-RICH INTERACTION DOMAIN (ARID)
Descriptor:BAF250b subunit
Authors:Shimada, A., Niwa, H., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-01
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the hBAF250b AT-rich interaction domain (ARID)
To be Published
2EH9
  • Download 2eh9
  • View 2eh9
Molmil generated image of 2eh9
CRYSTAL STRUCTURE OF THE HBAF250B AT-RICH INTERACTION DOMAIN (ARID)
Descriptor:AT-rich interactive domain-containing protein 1B, ZINC ION, CHLORIDE ION
Authors:Niwa, H., Shimada, A., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-05
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the HBAF250B at-rich interaction domain (ARID)
To be Published
2EQY
  • Download 2eqy
  • View 2eqy
Molmil generated image of 2eqy
SOLUTION STRUCTURE OF THE ARID DOMAIN OF JARID1B PROTEIN
Descriptor:Jumonji, AT rich interactive domain 1B
Authors:Tanabe, W., Suzuki, S., Muto, Y., Inoue, M., Kigawa, T., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-30
Release date:2007-10-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the ARID domain of Jarid1b protein
To be Published
2JRZ
  • Download 2jrz
  • View 2jrz
Molmil generated image of 2jrz
SOLUTION STRUCTURE OF THE BRIGHT/ARID DOMAIN FROM THE HUMAN JARID1C PROTEIN.
Descriptor:Histone demethylase JARID1C
Authors:Koehler, C., Bishop, S., Dowler, E.F., Diehl, A., Schmieder, P., Leidert, M., Sundstrom, M., Arrowsmith, C.H., Wiegelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)
Deposit date:2007-06-29
Release date:2007-07-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.
Biomol.Nmr Assign., 2, 2008
2JXJ
  • Download 2jxj
  • View 2jxj
Molmil generated image of 2jxj
NMR STRUCTURE OF THE ARID DOMAIN FROM THE HISTONE H3K4 DEMETHYLASE RBP2
Descriptor:Histone demethylase JARID1A
Authors:Tu, S., Yuan, C., Tsai, M.
Deposit date:2007-11-20
Release date:2008-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif
Nat.Struct.Mol.Biol., 15, 2008
2KK0
  • Download 2kk0
  • View 2kk0
Molmil generated image of 2kk0
SOLUTION STRUCTURE OF DEAD RINGER-LIKE PROTEIN 1 (AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A) FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4394C
Descriptor:AT-rich interactive domain-containing protein 3A
Authors:Liu, G., Wang, D., Nwosu, C., Owens, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-14
Release date:2009-07-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: a human cancer protein interaction network target.
Proteins, 78, 2010
2LI6
  • Download 2li6
  • View 2li6
Molmil generated image of 2li6
1H, 13C, AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR YEAST PROTEIN
Descriptor:SWI/SNF chromatin-remodeling complex subunit SWI1
Authors:Wang, T., Zhang, J., Tu, X.
Deposit date:2011-08-24
Release date:2012-04-25
Method:SOLUTION NMR
Cite:Solution structure of SWI1 ARID domain from Saccharomyces cerevisiae and its non-specific binding to DNA
Proteins, 2012
2LM1
  • Download 2lm1
  • View 2lm1
Molmil generated image of 2lm1
SOLUTION NMR STRUCTURE OF LYSINE-SPECIFIC DEMETHYLASE LID FROM DROSOPHILA MELANOGASTER, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR824D
Descriptor:Lysine-specific demethylase lid
Authors:Mills, J.L., Lee, D., Kohan, E., Sahdev, S., Acton, T.B., Xiao, R., Everett, J.K., Kusch, T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2011-11-18
Release date:2011-12-21
Last modified:2012-08-29
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target FR824D
To be Published
2OEH
  • Download 2oeh
  • View 2oeh
Molmil generated image of 2oeh
DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE MRF2-DNA COMPLEX USING PARAMAGNETIC SPIN LABELING
Descriptor:5'-D(P*TP*AP*CP*AP*AP*TP*AP*TP*AP*AP*CP*GP*TP*CP*G)-3', 5'-D(P*CP*GP*AP*CP*GP*TP*TP*AP*TP*AP*TP*TP*GP*T)-3', AT-rich interactive domain-containing protein 5B
Authors:Cai, S., Zhu, L., Zhang, Z.
Deposit date:2006-12-29
Release date:2007-08-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of the three-dimensional structure of the Mrf2-DNA complex using paramagnetic spin labeling.
Biochemistry, 46, 2007
2YQE
  • Download 2yqe
  • View 2yqe
Molmil generated image of 2yqe
SOLUTION STRUCTURE OF THE ARID DOMAIN OF JARID1D PROTEIN
Descriptor:Jumonji/ARID domain-containing protein 1D
Authors:Tanabe, W., Suzuki, S., Muto, Y., Inoue, M., Kigawa, T., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-30
Release date:2008-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the ARID domain of JARID1D protein
To be Published
5CEH
  • Download 5ceh
  • View 5ceh
Molmil generated image of 5ceh
STRUCTURE OF HISTONE LYSINE DEMETHYLASE KDM5A IN COMPLEX WITH SELECTIVE INHIBITOR
Descriptor:Lysine-specific demethylase 5A, Unknown Peptide, NICKEL (II) ION, ...
Authors:Kiefer, J.R., Vinogradova, M.
Deposit date:2015-07-06
Release date:2016-05-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Nat.Chem.Biol., 12, 2016
5K4L
  • Download 5k4l
  • View 5k4l
Molmil generated image of 5k4l
CRYSTAL STRUCTURE OF KDM5A IN COMPLEX WITH A NAPHTHYRIDONE INHIBITOR
Descriptor:Lysine-specific demethylase 5A, Unknown Peptide, NICKEL (II) ION, ...
Authors:Kiefer, J.R., Vinogradova, M.V.
Deposit date:2016-05-20
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (3.179 Å)
Cite:Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5V9P
  • Download 5v9p
  • View 5v9p
Molmil generated image of 5v9p
CRYSTAL STRUCTURE OF PYRROLIDINE AMIDE INHIBITOR [(3S)-3-(4-BROMO-1H-PYRAZOL-1-YL)PYRROLIDIN-1-YL][3-(PROPAN-2-YL)-1H-PYRAZOL-5-YL]METHANONE (COMPOUND 35) IN COMPLEX WITH KDM5A
Descriptor:Lysine-specific demethylase 5A, NICKEL (II) ION, ZINC ION, ...
Authors:Kiefer, J.R., Liang, J., Vinogradova, M.
Deposit date:2017-03-23
Release date:2017-05-10
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5V9T
  • Download 5v9t
  • View 5v9t
Molmil generated image of 5v9t
CRYSTAL STRUCTURE OF SELECTIVE PYRROLIDINE AMIDE KDM5A INHIBITOR N-{(3R)-1-[3-(PROPAN-2-YL)-1H-PYRAZOLE-5-CARBONYL]PYRROLIDIN-3-YL}CYCLOPROPANECARBOXAMIDE (COMPOUND 48)
Descriptor:Lysine-specific demethylase 5A, NICKEL (II) ION, ZINC ION, ...
Authors:Kiefer, J.R., Liang, J., Vinogradova, M.
Deposit date:2017-03-23
Release date:2017-05-10
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2018 Protein Data Bank Japan