1BGX
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TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB
Descriptor:TAQ DNA POLYMERASE, TP7 MAB
Authors:Murali, R., Sharkey, D.J., Daiss, J.L., Krishna Murthy, H.M.
Deposit date:1998-06-02
Release date:1998-10-14
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
1EXN
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T5 5'-EXONUCLEASE
Descriptor:5'-EXONUCLEASE
Authors:Ceska, T.A., Sayers, J.R., Stier, G., Suck, D.
Deposit date:1997-01-17
Release date:1997-07-07
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease.
Nature, 382, 1996
1TAQ
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STRUCTURE OF TAQ DNA POLYMERASE
Descriptor:TAQ DNA POLYMERASE, B-2-OCTYLGLUCOSIDE, ZINC ION
Authors:Kim, Y., Eom, S.H., Wang, J., Lee, D.-S., Suh, S.W., Steitz, T.A.
Deposit date:1996-06-04
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Thermus aquaticus DNA polymerase.
Nature, 376, 1995
1TAU
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TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX
Descriptor:DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), PROTEIN (TAQ POLYMERASE), ...
Authors:Eom, S.H., Wang, J., Steitz, T.A.
Deposit date:1996-06-17
Release date:1997-04-18
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Taq ploymerase with DNA at the polymerase active site.
Nature, 382, 1996
1UT5
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DIVALENT METAL IONS (MANGANESE) BOUND TO T5 5'-EXONUCLEASE
Descriptor:EXODEOXYRIBONUCLEASE, MANGANESE (II) ION
Authors:Ceska, T.A., Sayers, J.R., Suck, D.
Deposit date:2003-12-04
Release date:2004-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Roles of Divalent Metal Ions in Flap Endonuclease-Substrate Interactions
Nat.Struct.Mol.Biol., 11, 2004
1UT8
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DIVALENT METAL IONS (ZINC) BOUND TO T5 5'-EXONUCLEASE
Descriptor:EXODEOXYRIBONUCLEASE, ZINC ION
Authors:Ceska, T.A., Sayers, J.R., Suck, D.
Deposit date:2003-12-04
Release date:2004-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Roles of Divalent Metal Ions in Flap Endonuclease-Substrate Interactions
Nat.Struct.Mol.Biol., 11, 2004
1XO1
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T5 5'-EXONUCLEASE MUTANT K83A
Descriptor:5'-EXONUCLEASE
Authors:Ceska, T.A., Suck, D., Sayers, J.R.
Deposit date:1998-11-19
Release date:1999-04-02
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.
Proc.Natl.Acad.Sci.USA, 96, 1999
3ZD8
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POTASSIUM BOUND STRUCTURE OF E. COLI EXOIX IN P1
Descriptor:PROTEIN XNI, POTASSIUM ION
Authors:Anstey-Gilbert, C.S., Hemsworth, G.R., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZD9
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POTASSIUM BOUND STRUCTURE OF E. COLI EXOIX IN P21
Descriptor:PROTEIN XNI, POTASSIUM ION
Authors:Anstey-Gilbert, C.S., Hemsworth, G.R., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDA
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STRUCTURE OF E. COLI EXOIX IN COMPLEX WITH A FRAGMENT OF THE FLAP1 DNA OLIGONUCLEOTIDE, POTASSIUM AND MAGNESIUM
Descriptor:PROTEIN XNI, 5'-D(*GP*CP*GP*CP)-3', 5'-D(*AP*AP*GP*CP*GP*CP)-3', ...
Authors:Hemsworth, G.R., Anstey-Gilbert, C.S., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDB
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STRUCTURE OF E. COLI EXOIX IN COMPLEX WITH THE PALINDROMIC 5OV4 DNA OLIGONUCLEOTIDE, DI-MAGNESIUM AND POTASSIUM
Descriptor:PROTEIN XNI, 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ...
Authors:Hemsworth, G.R., Anstey-Gilbert, C.S., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDC
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STRUCTURE OF E. COLI EXOIX IN COMPLEX WITH THE PALINDROMIC 5OV4 DNA OLIGONUCLEOTIDE, POTASSIUM AND CALCIUM
Descriptor:PROTEIN XNI, 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ...
Authors:Hemsworth, G.R., Anstey-Gilbert, C.S., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDD
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STRUCTURE OF E. COLI EXOIX IN COMPLEX WITH THE PALINDROMIC 5OV6 OLIGONUCLEOTIDE AND POTASSIUM
Descriptor:PROTEIN XNI, 5OV6 DNA, POTASSIUM ION, ...
Authors:Flemming, C.S., Hemsworth, G.R., Anstey-Gilbert, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
3ZDE
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POTASSIUM FREE STRUCTURE OF E. COLI EXOIX
Descriptor:PROTEIN XNI
Authors:Hemsworth, G.R., Anstey-Gilbert, C.S., Flemming, C.S., Hodskinson, M.R.G., Zhang, J., Sedelnikova, S.E., Stillman, T.J., Sayers, J.R., Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
5HML
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CRYSTAL STRUCTURE OF T5 D15 PROTEIN CO-CRYSTALLIZED WITH METAL IONS
Descriptor:Exodeoxyribonuclease, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Flemming, C.S., Feng, M., Sedelnikova, S.E., Zhang, J., Rafferty, J.B., Sayers, J.R., Artymiuk, P.J.
Deposit date:2016-01-16
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
5HMM
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CRYSTAL STRUCTURE OF T5 D15 PROTEIN CO-CRYSTALLIZED WITH METAL IONS
Descriptor:Exodeoxyribonuclease, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Flemming, C.S., Sedelnikova, S.E., Rafferty, J.B., Sayers, J.R., Artymiuk, P.J.
Deposit date:2016-01-16
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
5HNK
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CRYSTAL STRUCTURE OF T5FEN IN COMPLEX INTACT SUBSTRATE AND METAL IONS.
Descriptor:DNA (5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*C)-3'), Exodeoxyribonuclease, MAGNESIUM ION, ...
Authors:Almalki, F.A., Feng, M., Zhang, J., Sedelnikova, S.E., Rafferty, J.B., Sayers, J.R., Artymiuk, P.J.
Deposit date:2016-01-18
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
5HP4
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CRYSTAL STRUCTURE BACTERIOHAGE T5 D15 FLAP ENDONUCLEASE (D155K) PSEUDO-ENZYME-PRODUCT COMPLEX WITH DNA AND METAL IONS
Descriptor:DNA (5'-D(*GP*AP*TP*CP*TP*AP*TP*AP*TP*GP*CP*CP*AP*TP*CP*GP*G)-3'), Exodeoxyribonuclease, CALCIUM ION, ...
Authors:Almalki, F.A., Zhang, J., Sedelnikova, S.E., Rafferty, J.B., Sayers, J.R., Artymiuk, P.A.
Deposit date:2016-01-20
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
6C33
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MYCOBACTERIUM SMEGMATIS DNA FLAP ENDONUCLEASE
Descriptor:5'-3' exonuclease, MANGANESE (II) ION
Authors:Shuman, S., Goldgur, Y., Carl, A., Uson, M.L.
Deposit date:2018-01-09
Release date:2018-03-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
6C34
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MYCOBACTERIUM SMEGMATIS DNA FLAP ENDONUCLEASE MUTANT D125N
Descriptor:5'-3' exonuclease, MANGANESE (II) ION
Authors:Shuman, S., Goldgur, Y., Carl, A., Uson, M.L.
Deposit date:2018-01-09
Release date:2018-03-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
6C35
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MYCOBACTERIUM SMEGMATIS FLAP ENDONUCLEASE MUTANT D148N
Descriptor:5'-3' exonuclease, MANGANESE (II) ION
Authors:Shuman, S., Goldgur, Y., Carl, A., Uson, M.L.
Deposit date:2018-01-09
Release date:2018-03-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
6C36
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MYCOBACTERIUM SMEGMATIS FLAP ENDONUCLEASE MUTANT D208N
Descriptor:5'-3' exonuclease, MANGANESE (II) ION, PHOSPHATE ION
Authors:Shuman, S., Goldgur, Y., Carl, A., Uson, M.L.
Deposit date:2018-01-09
Release date:2018-03-28
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
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