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7UWE
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CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
7UWH
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BU of 7uwh by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex bound to ribonucleotide substrate
Descriptor: DNA (59-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
5Y9P
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BU of 5y9p by Molmil
Staphylococcus aureus RNase HII
Descriptor: GLYCEROL, Ribonuclease HII
Authors:Hang, T, Wu, M, Zhang, X.
Deposit date:2017-08-26
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into a novel functional dimer of Staphylococcus aureus RNase HII
Biochem. Biophys. Res. Commun., 503, 2018
4PY5
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BU of 4py5 by Molmil
Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA
Descriptor: 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', GLYCEROL, ...
Authors:Figiel, M, Nowotny, M.
Deposit date:2014-03-26
Release date:2014-07-30
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.
Nucleic Acids Res., 42, 2014
4HHT
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BU of 4hht by Molmil
T. maritima RNase H2 G21S in complex with nucleic acid substrate and calcium ions
Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P, Nowotny, M.
Deposit date:2012-10-10
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:RNase H2 roles in genome integrity revealed by unlinking its activities.
Nucleic Acids Res., 41, 2013
3VN5
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BU of 3vn5 by Molmil
Crystal structure of Aquifex aeolicus RNase H3
Descriptor: Ribonuclease HIII
Authors:Jongruja, N, You, D.J, Eiko, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2011-12-22
Release date:2012-12-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure and characterization of RNase H3 from Aquifex aeolicus
Febs J., 279, 2012
3ASM
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BU of 3asm by Molmil
Crystal structure of Q54A mutant protein of Bst-RNase HIII
Descriptor: Ribonuclease HIII
Authors:Angkawidjaja, C, Kanaya, S.
Deposit date:2010-12-16
Release date:2011-06-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Identification of the substrate binding site in the N-terminal TBP-like domain of RNase H3.
Febs Lett., 585, 2011
3PUF
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BU of 3puf by Molmil
Crystal structure of human RNase H2 complex
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Figiel, M, Chon, H, Cerritelli, S.M, Cybulska, M, Crouch, R.J, Nowotny, M.
Deposit date:2010-12-04
Release date:2010-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects.
J.Biol.Chem., 286, 2011
3P83
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Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus.
Descriptor: DNA polymerase sliding clamp, Ribonuclease HII
Authors:Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
Deposit date:2010-10-13
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
3P56
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The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.06 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
3P5J
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BU of 3p5j by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
3O3F
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BU of 3o3f by Molmil
T. maritima RNase H2 D107N in complex with nucleic acid substrate and magnesium ions
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MAGNESIUM ION, ...
Authors:Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3O3H
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BU of 3o3h by Molmil
T. maritima RNase H2 D107N in complex with nucleic acid substrate and manganese ions
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MANGANESE (II) ION, ...
Authors:Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3O3G
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BU of 3o3g by Molmil
T. maritima RNase H2 in complex with nucleic acid substrate and calcium ions
Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3KIO
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BU of 3kio by Molmil
mouse RNase H2 complex
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Shaban, N, Harvey, S, Perrino, F.W, Hollis, T.
Deposit date:2009-11-02
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction.
J.Biol.Chem., 285, 2010
2DFH
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BU of 2dfh by Molmil
Crystal structure of Tk-RNase HII(1-212)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
2DFE
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BU of 2dfe by Molmil
Crystal structure of Tk-RNase HII(1-200)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
2DFF
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BU of 2dff by Molmil
Crystal structure of Tk-RNase HII(1-204)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
2ETJ
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BU of 2etj by Molmil
Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-10-27
Release date:2005-11-08
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution
To be published
2D0C
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BU of 2d0c by Molmil
Crystal structure of Bst-RNase HIII in complex with Mn2+
Descriptor: MANGANESE (II) ION, ribonuclease HIII
Authors:Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2005-07-31
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus
J.Mol.Biol., 356, 2006
2D0B
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BU of 2d0b by Molmil
Crystal structure of Bst-RNase HIII in complex with Mg2+
Descriptor: MAGNESIUM ION, ribonuclease HIII
Authors:Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2005-07-31
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus
J.Mol.Biol., 356, 2006
2D0A
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BU of 2d0a by Molmil
Crystal structure of Bst-RNase HIII
Descriptor: ribonuclease HIII
Authors:Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2005-07-31
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus
J.Mol.Biol., 356, 2006
1X1P
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BU of 1x1p by Molmil
Crystal structure of Tk-RNase HII(1-197)-A(28-42)
Descriptor: Ribonuclease HII
Authors:Takano, K, Endo, S, Mukaiyama, A, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2005-04-11
Release date:2006-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of amyloid beta fragments in aqueous environments
Febs J., 273, 2006
1UAX
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BU of 1uax by Molmil
Crystal structure of the ribonuclease H2 from Pyrococcus horikoshii OT3
Descriptor: Ribonuclease HII
Authors:Hata, T, Numata, T, Kakuta, Y, Kimura, M.
Deposit date:2003-03-24
Release date:2004-06-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the ribonuclease H2 from Pyrococcus horikoshii OT3
To be published
1I3A
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BU of 1i3a by Molmil
RNASE HII FROM ARCHAEOGLOBUS FULGIDUS WITH COBALT HEXAMMINE CHLORIDE
Descriptor: COBALT HEXAMMINE(III), RIBONUCLEASE HII
Authors:Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A.
Deposit date:2001-02-13
Release date:2001-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication.
J.Mol.Biol., 307, 2001

 

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