6O5C
 
 | | X-ray crystal structure of metal-dependent transcriptional regulator MtsR | | Descriptor: | DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Putative metal-dependent transcriptional regulator | | Authors: | Do, H, Kumaraswami, M. | | Deposit date: | 2019-03-01 | | Release date: | 2019-06-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res., 47, 2019
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5CVI
 | | Structure of the manganese regulator SloR | | Descriptor: | 1,2-ETHANEDIOL, SloR, ZINC ION | | Authors: | Nye, D, Glasfeld, A. | | Deposit date: | 2015-07-27 | | Release date: | 2015-08-12 | | Last modified: | 2020-02-26 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | SloR structure and DNA binding studies inform the SloR-SRE interaction in Streptococcus mutans
to be published
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2TDX
 | | DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL | | Descriptor: | DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | | Authors: | White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R. | | Deposit date: | 1998-06-22 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
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3R60
 | | Structure of the MntR Fe2+ Complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE (II) ION, S-1,2-PROPANEDIOL, ... | | Authors: | Glasfeld, A, Brophy, M.B, Kliegman, J.I, Griner, S.L, Nix, J.C. | | Deposit date: | 2011-03-20 | | Release date: | 2012-04-11 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Roles of the A and C Sites in the Manganese-Specific Activation of MntR.
Biochemistry, 52, 2013
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3R61
 | | Structure of the MntR Co2+ Complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, Transcriptional regulator mntR | | Authors: | Glasfeld, A, Brophy, M.B, Kliegman, J.I, Griner, S.L, Nix, J.C. | | Deposit date: | 2011-03-20 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9002 Å) | | Cite: | Roles of the A and C Sites in the Manganese-Specific Activation of MntR.
Biochemistry, 52, 2013
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1U8R
 | | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions | | Descriptor: | COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ... | | Authors: | Wisedchaisri, G, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-10-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
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5ZR6
 | | Manganese-dependent transcriptional repressor complex with manganese | | Descriptor: | MANGANESE (II) ION, Metal-dependent transcriptional regulator | | Authors: | Cong, X.Y, Xu, S.J, Wang, J.B. | | Deposit date: | 2018-04-23 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of manganese-dependent transcriptional repressor MntR (Rv2788) from Mycobacterium tuberculosis in apo and manganese bound forms.
Biochem. Biophys. Res. Commun., 501, 2018
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5ZR4
 | | Manganese-dependent transcriptional repressor | | Descriptor: | Metal-dependent transcriptional regulator | | Authors: | Cong, X.Y, Gu, L.C, Wang, J.B. | | Deposit date: | 2018-04-23 | | Release date: | 2019-01-23 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of manganese-dependent transcriptional repressor MntR (Rv2788) from Mycobacterium tuberculosis in apo and manganese bound forms.
Biochem. Biophys. Res. Commun., 501, 2018
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2X4H
 | | Crystal Structure of the hypothetical protein SSo2273 from Sulfolobus solfataricus | | Descriptor: | HYPOTHETICAL PROTEIN SSO2273, ZINC ION | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-01-31 | | Release date: | 2010-07-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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6KTB
 | | Crystal structure of B. halodurans MntR in apo form | | Descriptor: | HTH-type transcriptional regulator MntR, MAGNESIUM ION, MANGANESE (II) ION, ... | | Authors: | Lee, J.Y, Lee, M.Y. | | Deposit date: | 2019-08-26 | | Release date: | 2019-12-04 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis of the manganese transport regulator MntR from Bacillus halodurans in apo and manganese bound forms.
Plos One, 14, 2019
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6KTA
 | | Crystal structure of B. halodurans MntR in apo form | | Descriptor: | GLYCEROL, HTH-type transcriptional regulator MntR | | Authors: | Lee, J.Y, Lee, M.Y. | | Deposit date: | 2019-08-26 | | Release date: | 2019-12-04 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural analysis of the manganese transport regulator MntR from Bacillus halodurans in apo and manganese bound forms.
Plos One, 14, 2019
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1XCV
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1ON1
 | | Bacillus Subtilis Manganese Transport Regulator (Mntr) Bound To Manganese, AB Conformation. | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Glasfeld, A, Guedon, E, Helmann, J.D, Brennan, R.G. | | Deposit date: | 2003-02-26 | | Release date: | 2003-07-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis
Nat.Struct.Biol., 10, 2003
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1P92
 | | Crystal Structure of (H79A)DtxR | | Descriptor: | BETA-MERCAPTOETHANOL, Diphtheria toxin repressor | | Authors: | D'Aquino, J.A, Ringe, D. | | Deposit date: | 2003-05-08 | | Release date: | 2004-05-25 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Determinants of the SRC homology domain 3-like fold.
J.Bacteriol., 185, 2003
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1ON2
 | | Bacillus subtilis Manganese Transport Regulator (MntR), D8M Mutant, Bound to Manganese | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Glasfeld, A, Guedon, E, Helmann, J.D, Brennan, R.G. | | Deposit date: | 2003-02-26 | | Release date: | 2003-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis
Nat.Struct.Biol., 10, 2003
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2QQ9
 | | Crystal Structure of DtxR(D6A C102D) Complexed with Nickel(II) | | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | | Deposit date: | 2007-07-26 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
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2QQA
 | | Crystal Structure of DtxR(E9A C102D) Complexed with Nickel(II) | | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | | Deposit date: | 2007-07-26 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
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2QQB
 | | Crystal Structure of DtxR(M10A C102D) Complexed with Nickel(II) | | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | | Deposit date: | 2007-07-26 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
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1FX7
 | | CRYSTAL STRUCTURE OF THE IRON-DEPENDENT REGULATOR (IDER) FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | COBALT (II) ION, IRON-DEPENDENT REPRESSOR IDER, SULFATE ION | | Authors: | Feese, M.D, Ingason, B.P, Goranson-Siekierke, J, Holmes, R.K, Hol, W.J.G. | | Deposit date: | 2000-09-25 | | Release date: | 2001-03-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
J.Biol.Chem., 276, 2001
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1FWZ
 | | GLU20ALA DTXR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-09-25 | | Release date: | 2001-09-25 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3T
 | | CYS102SER DTXR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-10-25 | | Release date: | 2001-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3W
 | | CD-CYS102SER DTXR | | Descriptor: | CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-10-25 | | Release date: | 2001-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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3GLX
 | | Crystal Structure Analysis of the DtxR(E175K) complexed with Ni(II) | | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | | Authors: | D'Aquino, J.A, Denninger, A, Moulin, A, D'Aquino, K.E, Ringe, D. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Decreased sensitivity to changes in the concentration of metal ions as the basis for the hyperactivity of DtxR(E175K).
J.Mol.Biol., 390, 2009
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3HRT
 | | Crystal Structure of ScaR with bound Cd2+ | | Descriptor: | CADMIUM ION, Metalloregulator ScaR, SULFATE ION | | Authors: | Stoll, K.E, Draper, W.E, Kliegman, J.I, Golynskiy, M.V, Brew-Appiah, R.A.T, Brown, H.K, Breyer, W.A, Jakubovics, N.S, Jenkinson, H.F, Brennan, R.B, Cohen, S.M, Glasfeld, A. | | Deposit date: | 2009-06-09 | | Release date: | 2009-06-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
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3HRS
 | | Crystal Structure of the Manganese-activated Repressor ScaR: apo form | | Descriptor: | Metalloregulator ScaR, SULFATE ION | | Authors: | Stoll, K.E, Draper, W.E, Kliegman, J.I, Golynskiy, M.V, Brew-Appiah, R.A.T, Brown, H.K, Breyer, W.A, Jakubovics, N.S, Jenkinson, H.F, Brennan, R.B, Cohen, S.M, Glasfeld, A. | | Deposit date: | 2009-06-09 | | Release date: | 2009-06-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
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