1F5T
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DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
Descriptor:43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION
Authors:Chen, S., White, A., Love, J., Murphy, J.R., Ringe, D.
Deposit date:2000-06-15
Release date:2000-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Biochemistry, 39, 2000
1B1B
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IRON DEPENDENT REGULATOR
Descriptor:PROTEIN (IRON DEPENDENT REGULATOR), ZINC ION, SULFATE ION
Authors:Pohl, E., Holmes, R.K., Hol, W.G.
Deposit date:1998-11-19
Release date:1999-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied.
J.Mol.Biol., 285, 1999
1BI0
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STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, ZINC ION, SULFATE ION
Authors:Pohl, E., Hol, W.G.
Deposit date:1998-06-21
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1BI1
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STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E., Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1BI2
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STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E., Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1BI3
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STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, ZINC ION, SULFATE ION
Authors:Pohl, E., Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1C0W
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CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
Descriptor:DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*GP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), DIPHTHERIA TOXIN REPRESSOR, ...
Authors:Pohl, E., Holmes, R.K., Hol, W.G.
Deposit date:1999-07-22
Release date:2000-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
J.Mol.Biol., 292, 1999
1DDN
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DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
Descriptor:33 BASE DNA CONTAINING TOXIN OPERATOR, DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION
Authors:White, A., Ding, X., Vanderspek, J.C., Murphy, J.R., Ringe, D.
Deposit date:1998-06-23
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
1DPR
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STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE
Descriptor:DIPHTHERIA TOX REPRESSOR
Authors:Schiering, N., Tao, X., Murphy, J., Petsko, G.A., Ringe, D.
Deposit date:1995-02-06
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FWZ
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GLU20ALA DTXR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION
Authors:Pohl, E., Goranson-Siekierke, J., Holmes, R.K., Hol, W.G.J.
Deposit date:2000-09-25
Release date:2001-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1FX7
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CRYSTAL STRUCTURE OF THE IRON-DEPENDENT REGULATOR (IDER) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:IRON-DEPENDENT REPRESSOR IDER, SULFATE ION, COBALT (II) ION
Authors:Feese, M.D., Ingason, B.P., Goranson-Siekierke, J., Holmes, R.K., Hol, W.J.G.
Deposit date:2000-09-25
Release date:2001-03-07
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
J.Biol.Chem., 276, 2001
1G3S
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CYS102SER DTXR
Descriptor:DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E., Goranson-Siekierke, J., Holmes, R.K., Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3T
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CYS102SER DTXR
Descriptor:DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E., Goranson-Siekierke, J., Holmes, R.K., Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3W
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CD-CYS102SER DTXR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, CADMIUM ION, SULFATE ION
Authors:Pohl, E., Goranson-Siekierke, J., Holmes, R.K., Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3Y
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ARG80ALA DTXR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, ZINC ION
Authors:Pohl, E., Goranson-Siekierke, J., Holmes, R.K., Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1ON1
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR) BOUND TO MANGANESE, AB CONFORMATION.
Descriptor:Transcriptional regulator mntR, MANGANESE (II) ION
Authors:Glasfeld, A., Guedon, E., Helmann, J.D., Brennan, R.G.
Deposit date:2003-02-26
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis
Nat.Struct.Biol., 10, 2003
1ON2
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR), D8M MUTANT, BOUND TO MANGANESE
Descriptor:Transcriptional regulator mntR, MANGANESE (II) ION
Authors:Glasfeld, A., Guedon, E., Helmann, J.D., Brennan, R.G.
Deposit date:2003-02-26
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis
Nat.Struct.Biol., 10, 2003
1P92
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CRYSTAL STRUCTURE OF (H79A)DTXR
Descriptor:Diphtheria toxin repressor, BETA-MERCAPTOETHANOL
Authors:D'Aquino, J.A., Ringe, D.
Deposit date:2003-05-08
Release date:2004-05-25
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Determinants of the SRC homology domain 3-like fold.
J.Bacteriol., 185, 2003
1U8R
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CRYSTAL STRUCTURE OF AN IDER-DNA COMPLEX REVEALS A CONFORMATIONAL CHANGE IN ACTIVATED IDER FOR BASE-SPECIFIC INTERACTIONS
Descriptor:mbtA operator DNA, mbtB operator DNA, Iron-dependent repressor ideR, ...
Authors:Wisedchaisri, G., Holmes, R.K., Hol, W.G.J.
Deposit date:2004-08-06
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
1XCV
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CRYSTAL STRUCTURE OF (H79AC102D)DTXR COMPLEXED WITH NICKEL(II)
Descriptor:Diphtheria toxin repressor mutant, NICKEL (II) ION
Authors:D'aquino, J.A., Ringe, D.
Deposit date:2004-09-03
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
Proc.Natl.Acad.Sci.USA, 102, 2005
2DTR
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STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR
Descriptor:DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, COBALT (II) ION
Authors:Qiu, X., Pohl, E., Hol, W.G.
Deposit date:1996-07-26
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
Biochemistry, 35, 1996
2EV0
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR) BOUND TO CADMIUM
Descriptor:Transcriptional regulator mntR, CADMIUM ION
Authors:Kliegman, J.I., Griner, S.L., Helmann, J.D., Brennan, R.G., Glasfeld, A.
Deposit date:2005-10-30
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2EV5
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR) BOUND TO CALCIUM
Descriptor:Transcriptional regulator mntR, CALCIUM ION
Authors:Kliegman, J.I., Griner, S.L., Helmann, J.D., Brennan, R.G., Glasfeld, A.
Deposit date:2005-10-31
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2EV6
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR) BOUND TO ZINC
Descriptor:Transcriptional regulator mntR, ZINC ION, GLYCEROL, ...
Authors:Kliegman, J.I., Griner, S.L., Helmann, J.D., Brennan, R.G., Glasfeld, A.
Deposit date:2005-10-31
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2F5C
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BACILLUS SUBTILIS MANGANESE TRANSPORT REGULATOR (MNTR) BOUND TO MANGANESE, HEXAGONAL CRYSTAL FORM
Descriptor:Transcriptional regulator mntR, MANGANESE (II) ION, SULFATE ION
Authors:Kliegman, J.I., Griner, S.L., Helmann, J.D., Brennan, R.G., Glasfeld, A.
Deposit date:2005-11-25
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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