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1PFO
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BU of 1pfo by Molmil
PERFRINGOLYSIN O
Descriptor: PERFRINGOLYSIN O
Authors:Rossjohn, J, Parker, M.W.
Deposit date:1997-07-31
Release date:1998-08-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form.
Cell(Cambridge,Mass.), 89, 1997
1M3J
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BU of 1m3j by Molmil
CRYSTAL form II of perfringolysin O
Descriptor: perfringolysin o
Authors:Rossjohn, J, Parker, M, Polekhina, G, Feil, S, Tweten, R.
Deposit date:2002-06-28
Release date:2003-09-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:STRUCTURAL SNAPSHOTS IN THE MOLECULAR MECHANISM OF PFO REVEALED
To be Published
1M3I
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BU of 1m3i by Molmil
Perfringolysin O, new crystal form
Descriptor: perfringolysin O
Authors:Rossjohn, J, Parker, M, Polekhina, G, Feil, S, Tweten, R.
Deposit date:2002-06-28
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Snapshots in the Molecular Mechanism of PFO Revealed
To be Published
1S3R
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BU of 1s3r by Molmil
Crystal structure of the human-specific toxin intermedilysin
Descriptor: SULFATE ION, intermedilysin
Authors:Polekhina, G, Giddings, K.S, Tweten, R.K, Parker, M.W.
Deposit date:2004-01-14
Release date:2005-01-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin
Proc.Natl.Acad.Sci.Usa, 102, 2005
2BK2
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BU of 2bk2 by Molmil
The prepore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map
Descriptor: PERFRINGOLYSIN O
Authors:Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2013-01-16
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
2BK1
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BU of 2bk1 by Molmil
The pore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map
Descriptor: PERFRINGOLYSIN O
Authors:Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (29 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
3CQF
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BU of 3cqf by Molmil
Crystal structure of anthrolysin O (ALO)
Descriptor: Thiol-activated cytolysin
Authors:Bourdeau, R.W, Malito, E, Tang, W.J.
Deposit date:2008-04-02
Release date:2009-03-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis
J.Biol.Chem., 284, 2009
3HVN
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BU of 3hvn by Molmil
Crystal structure of cytotoxin protein suilysin from Streptococcus suis
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, HEPTANE-1,2,3-TRIOL, Hemolysin
Authors:Xu, L, Huang, B, Du, H, Zhang, C.X, Xu, J, Li, X, Rao, Z.
Deposit date:2009-06-16
Release date:2010-03-02
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.852 Å)
Cite:Crystal structure of cytotoxin protein suilysin from Streptococcus suis.
Protein Cell, 1, 2010
4HSC
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BU of 4hsc by Molmil
Crystal structure of a cholesterol dependent cytolysin
Descriptor: Streptolysin O
Authors:Feil, S.C, Parker, M.W.
Deposit date:2012-10-29
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.
J.Mol.Biol., 426, 2014
4BIK
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BU of 4bik by Molmil
Structure of a disulfide locked mutant of Intermedilysin with human CD59
Descriptor: CD59 GLYCOPROTEIN, INTERMEDILYSIN
Authors:Johnson, S, Brooks, N.J, Smith, R.A.G, Lea, S.M, Bubeck, D.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.494 Å)
Cite:Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59
Cell Rep., 3, 2013
4CDB
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BU of 4cdb by Molmil
Crystal structure of listeriolysin O
Descriptor: ACETATE ION, LISTERIOLYSIN O, SODIUM ION, ...
Authors:Koester, S, Yildiz, O.
Deposit date:2013-10-30
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Listeriolysin O Reveals Molecular Details of Oligomerization and Pore Formation
Nat.Commun., 5, 2014
4QQA
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BU of 4qqa by Molmil
Crystal structure of pneumolysin from Streptococcus pneumoniae
Descriptor: Pneumolysin
Authors:Park, S.A, Lee, K.S.
Deposit date:2014-06-27
Release date:2015-08-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Crystal structure of pneumolysin from Streptococcus pneumoniae
To be Published
4QQQ
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Crystal structure of pneumolysin from Streptococcus pneumoniae, in complex with mannose as a component of cell membrane
Descriptor: Pneumolysin, alpha-D-mannopyranose
Authors:Park, S.A, Lee, K.S.
Deposit date:2014-06-27
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of pneumolysin from Streptococcus pneumoniae, in complex with mannose as a component of cell membrane
To be Published
4ZGH
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BU of 4zgh by Molmil
Structure of Sugar Binding Protein Pneumolysin
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GOLD (I) CYANIDE ION, ...
Authors:Parker, M.W, Feil, S.C, Morton, C.
Deposit date:2015-04-23
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation.
Sci Rep, 5, 2015
5CR6
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BU of 5cr6 by Molmil
Structure of pneumolysin at 1.98 A resolution
Descriptor: Pneumolysin
Authors:Marshall, J.E, Faraj, B.H.A, Gingras, A.R, Lonnen, R, Sheikh, M.A, El-Mezgueldi, M, Moody, P.C.E, Andrew, P.W, Wallis, R.
Deposit date:2015-07-22
Release date:2015-09-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Crystal Structure of Pneumolysin at 2.0 angstrom Resolution Reveals the Molecular Packing of the Pre-pore Complex.
Sci Rep, 5, 2015
5DHL
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BU of 5dhl by Molmil
Crystal structure of Toxin, mutant N197W
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
Authors:Parker, M.W, Gorman, M.A, Lawrence, S.L.
Deposit date:2015-08-31
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structure of mutant toxin
To Be Published
5DIM
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BU of 5dim by Molmil
Mutant toxin in 'native' space group
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
Authors:Parker, M.W, Gorman, M.A, Lawrence, S.L.
Deposit date:2015-09-01
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of mutant toxin at 3.32 Angstrom resolution
To Be Published
5AOF
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BU of 5aof by Molmil
Crystal structure of pneumolysin deletion mutant Delta146_147.
Descriptor: PNEUMOLYSIN
Authors:van Pee, K, Yildiz, O.
Deposit date:2015-09-10
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.
Elife, 6, 2017
5AOD
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BU of 5aod by Molmil
Crystal structure of wild type pneumolysin.
Descriptor: PNEUMOLYSIN
Authors:van Pee, K, Yildiz, O.
Deposit date:2015-09-10
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Wild Type Pneumolysin
To be Published
5AOE
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BU of 5aoe by Molmil
Crystal structure of pneumolysin D168A mutant.
Descriptor: PNEUMOLYSIN
Authors:van Pee, K, Yildiz, O.
Deposit date:2015-09-10
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.
Elife, 6, 2017
5IMT
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BU of 5imt by Molmil
Toxin receptor complex
Descriptor: CD59 glycoprotein, COPPER (II) ION, Intermedilysin, ...
Authors:Morton, C.J, Lawrence, S.L, Feil, S.C, Parker, M.W.
Deposit date:2016-03-06
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7001 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5IMW
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BU of 5imw by Molmil
Trapped Toxin
Descriptor: Intermedilysin
Authors:Lawrence, S.L, Feil, S.C, Morton, C.J, Parker, M.W.
Deposit date:2016-03-07
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5IMY
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BU of 5imy by Molmil
Trapped Toxin
Descriptor: CD59 glycoprotein, Vaginolysin
Authors:Lawrence, S.L, Morton, C.J, Parker, M.W.
Deposit date:2016-03-07
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5LY6
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BU of 5ly6 by Molmil
CryoEM structure of the membrane pore complex of Pneumolysin at 4.5A
Descriptor: Pneumolysin
Authors:van Pee, K, Neuhaus, A, D'Imprima, E, Mills, D.J, Kuehlbrandt, W, Yildiz, O.
Deposit date:2016-09-24
Release date:2017-04-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.
Elife, 6, 2017
6JMP
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BU of 6jmp by Molmil
Crystal Structure of a Non-hemolytic Pneumolysin from Streptococcus pneumoniae strain ST306
Descriptor: GLYCEROL, Thiol-activated cytolysin
Authors:Badgujar, D.C, Bhaumik, P.
Deposit date:2019-03-13
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle.
Plos Pathog., 16, 2020

 

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