1ZHT
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STRUCTURE OF YEAST OXYSTEROL BINDING PROTEIN OSH4 IN COMPLEX WITH 7-HYDROXYCHOLESTEROL
Descriptor:KES1 protein, 7-HYDROXYCHOLESTEROL
Authors:Im, Y.J., Raychaudhuri, S., Prinz, W.A., Hurley, J.H.
Deposit date:2005-04-26
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
1ZHW
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STRUCTURE OF YEAST OXYSTEROL BINDING PROTEIN OSH4 IN COMPLEX WITH 20-HYDROXYCHOLESTEROL
Descriptor:KES1 protein, LEAD (II) ION, 20-HYDROXYCHOLESTEROL
Authors:Im, Y.J., Raychaudhuri, S., Prinz, W.A., Hurley, J.H.
Deposit date:2005-04-26
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
1ZHX
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STRUCTURE OF YEAST OXYSTEROL BINDING PROTEIN OSH4 IN COMPLEX WITH 25-HYDROXYCHOLESTEROL
Descriptor:KES1 protein, 25-HYDROXYCHOLESTEROL
Authors:Im, Y.J., Raychaudhuri, S., Prinz, W.A., Hurley, J.H.
Deposit date:2005-04-26
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
1ZHY
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STRUCTURE OF YEAST OXYSTEROL BINDING PROTEIN OSH4 IN COMPLEX WITH CHOLESTEROL
Descriptor:KES1 protein, LEAD (II) ION, CHOLESTEROL
Authors:Im, Y.J., Raychaudhuri, S., Prinz, W.A., Hurley, J.H.
Deposit date:2005-04-26
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
1ZHZ
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STRUCTURE OF YEAST OXYSTEROL BINDING PROTEIN OSH4 IN COMPLEX WITH ERGOSTEROL
Descriptor:KES1 protein, LEAD (II) ION, ERGOSTEROL
Authors:Im, Y.J., Raychaudhuri, S., Prinz, W.A., Hurley, J.H.
Deposit date:2005-04-26
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
3SPW
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STRUCTURE OF OSH4P/KES1P IN COMPLEX WITH PHOSPHATIDYLINOSITOL 4-PHOSPHATE
Descriptor:Protein KES1, (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
Authors:Delfosse, V., de Saint-Jean, M., Douguet, D., Antonny, B., Drin, G., Bourguet, W.
Deposit date:2011-07-04
Release date:2011-11-23
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers.
J.Cell Biol., 195, 2011
4B2Z
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STRUCTURE OF OSH6 IN COMPLEX WITH PHOSPHATIDYLSERINE
Descriptor:OXYSTEROL-BINDING PROTEIN HOMOLOG 6, SULFATE ION, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Maeda, K., Anand, K., Chiapparino, A., Kumar, A., Poletto, M., Kaksonen, M., Gavin, A.C.
Deposit date:2012-07-19
Release date:2013-06-26
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins
Nature, 501, 2013
4F4B
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STRUCTURE OF OSH4 WITH A CHOLESTEROL ANALOG
Descriptor:Protein KES1, (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione
Authors:Koag, M.C., Monzingo, A.F., Cheun, Y., Lee, S.
Deposit date:2012-05-10
Release date:2013-05-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
4FES
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STRUCTURE OF OSH4 IN COMPLEX WITH CHOLESTEROL ANALOGS
Descriptor:Protein KES1, (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one
Authors:Koag, M.C., Monzingo, A.F., Cheun, Y., Lee, S.
Deposit date:2012-05-30
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
4IC4
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CRYSTAL STRUCTURE OF OSH3 ORD FROM SACCHAROMYCES CEREVISIAE
Descriptor:Oxysterol-binding protein homolog 3
Authors:Tong, J., Im, Y.J.
Deposit date:2012-12-09
Release date:2013-07-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
4INQ
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CRYSTAL STRUCTURE OF OSH3 ORD IN COMPLEX WITH PI(4)P FROM SACCHAROMYCES CEREVISIAE
Descriptor:Oxysterol-binding protein homolog 3, (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate
Authors:Tong, J., Im, Y.J.
Deposit date:2013-01-05
Release date:2013-07-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
4JCH
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OSH4 BOUND TO AN ELECTROPHILIC OXYSTEROL
Descriptor:Protein KES1, (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate
Authors:Koag, M.C., Kou, Y.I., Monzingo, A.F., Lee, S.
Deposit date:2013-02-21
Release date:2014-03-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of OSH4 bound to an electrophilic oxysterol
To be Published
4PH7
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STRUCTURE OF OSH6P IN COMPLEX WITH PHOSPHATIDYLINOSITOL 4-PHOSPHATE
Descriptor:Oxysterol-binding protein homolog 6, (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
Authors:Delfosse, V., Moser von Filseck, J., Antonny, B., Bourguet, W., Drin, G.
Deposit date:2014-05-05
Release date:2015-07-29
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate.
Science, 349, 2015
5H2D
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CRYSTAL STRUCTURE OF OSH1 ORD DOMAIN IN COMPLEX WITH ERGOSTEROL
Descriptor:KLLA0C04147p, ERGOSTEROL, SULFATE ION
Authors:Im, Y.J., Manik, M.K., Yang, H.S., Tong, J.S.
Deposit date:2016-10-14
Release date:2017-05-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5WVR
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CRYSTAL STRUCTURE OF OSH1 ORD DOMAIN IN COMPLEX WITH CHOLESTEROL
Descriptor:KLLA0C04147p, CHOLESTEROL, SULFATE ION
Authors:Im, Y.J., Manik, M.K., Yang, H.S., Tong, J.S.
Deposit date:2016-12-28
Release date:2017-05-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
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