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6X9N	Pseudomonas aeruginosa MurC with AZ5595 Descriptor: (2R)-2-({4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)-2-phenylethan-1-ol, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Horanyi, P.S, Mayclin, S.J, Durand-Reville, T.F, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-06-03 Release date: 2020-09-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Pseudomonas aeruginosa MurC with AZ5595 To Be Published
1J6U	Crystal structure of UDP-N-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution Descriptor: UDP-N-acetylmuramate-alanine ligase MurC Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2002-08-29 Release date: 2002-11-06 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Proteins, 55, 2004
3HN7	Crystal structure of a murein peptide ligase mpl (psyc_0032) from psychrobacter arcticus 273-4 at 1.65 A resolution Descriptor: UDP-N-acetylmuramate-L-alanine ligase Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-05-29 Release date: 2009-06-16 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure and function of the first full-length murein Peptide ligase (mpl) cell wall recycling protein. Plos One, 6, 2011
4HV4	2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, BETA-MERCAPTOETHANOL, UDP-N-acetylmuramate--L-alanine ligase Authors: Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-11-05 Release date: 2012-11-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: 2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP To be Published
4ZIY	Structure of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase from Acinetobacter baumannii Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-04-28 Release date: 2015-05-20 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase from Acinetobacter baumannii to be published
5VVW	Structure of MurC from Pseudomonas aeruginosa Descriptor: 1,2-ETHANEDIOL, UDP-N-acetylmuramate--L-alanine ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-05-21 Release date: 2017-05-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of MurC from Pseudomonas aeruginosa To Be Published
8DOF	Pseudomonas aeruginosa MurC with WYH9-2-P - OSA_001044 Descriptor: (2R)-2-cyclohexyl-2-[(4-{[5-(propan-2-yl)-1H-pyrazol-3-yl]amino}-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]ethan-1-ol, 1,2-ETHANEDIOL, SULFATE ION, ... Authors: Horanyi, P.S, Wang, Y, Todd, M.H, Abendroth, J, Edwards, T, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-07-13 Release date: 2022-08-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Pseudomonas aeruginosa MurC with WYH9-2-P - OSA_001044 To Be Published
3EAG	The crystal structure of UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (MPL) from Neisseria meningitides Descriptor: GLYCEROL, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Authors: Chang, C, Hendricks, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2008-08-25 Release date: 2008-09-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The crystal structure of UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (MPL) from Neisseria meningitides To be Published
6X9F	Pseudomonas aeruginosa MurC with AZ8074 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Horanyi, P.S, Mayclin, S.J, Durand-Reville, T.F, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-06-02 Release date: 2020-09-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Pseudomonas aeruginosa MurC with AZ8074 To Be Published
6CAU	UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UDP-N-acetylmuramate--L-alanine ligase Authors: Horanyi, P.S, Abendroth, J, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-01-31 Release date: 2018-03-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP To be Published
1P3D	Crystal Structure of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) in Complex with UMA and ANP. Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UDP-N-acetylmuramate--alanine ligase, ... Authors: Mol, C.D, Brooun, A, Dougan, D.R, Hilgers, M.T, Tari, L.W, Wijnands, R.A, Knuth, M.W, McRee, D.E, Swanson, R.V. Deposit date: 2003-04-17 Release date: 2003-07-15 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:L-Alanine Ligase (MurC) from Haemophilus influenzae. J.Bacteriol., 185, 2003
1P31	Crystal Structure of UDP-N-acetylmuramic acid:L-alanine Ligase (MurC) from Haemophilus influenzae Descriptor: MAGNESIUM ION, UDP-N-acetylmuramate--alanine ligase, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID Authors: Mol, C.D, Brooun, A, Dougan, D.R, Hilgers, M.T, Tari, L.W, Wijnands, R.A, Knuth, M.W, McRee, D.E, Swanson, R.V. Deposit date: 2003-04-16 Release date: 2003-07-15 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:L-Alanine Ligase (MurC) from Haemophilus influenzae. J.Bacteriol., 185, 2003
2WTZ	MurE ligase of Mycobacterium Tuberculosis Descriptor: MAGNESIUM ION, UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE-D-GLUTAMATE Authors: Basavannacharya, C, Robertson, G, Munshi, T, Keep, N.H, Bhakta, S. Deposit date: 2009-09-25 Release date: 2009-12-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: ATP-Dependent Mure Ligase in Mycobacterium Tuberculosis: Biochemical and Structural Characterisation. Tuberculosis(Edinb.), 90, 2010
2XJA	Structure of MurE from M.tuberculosis with dipeptide and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ... Authors: Basavannacharya, C, Moody, P.R, Bhakta, S, Keep, N. Deposit date: 2010-07-03 Release date: 2010-08-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Essential Residues for the Enzyme Activity of ATP-Dependent Mure Ligase from Mycobacterium Tuberculosis. Protein Cell, 1, 2010
4QDI	Crystal structure II of MurF from Acinetobacter baumannii Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: An, Y.J, Jeong, C.S, Cha, S.S. Deposit date: 2014-05-13 Release date: 2015-04-01 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: ATP-binding mode including a carbamoylated lysine and two Mg(2+) ions, and substrate-binding mode in Acinetobacter baumannii MurF Biochem.Biophys.Res.Commun., 450, 2014
4QF5	Crystal structure I of MurF from Acinetobacter baumannii Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Authors: An, Y.J, Jeong, C.S, Cha, S.S. Deposit date: 2014-05-19 Release date: 2015-04-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: ATP-binding mode including a carbamoylated lysine and two Mg(2+) ions, and substrate-binding mode in Acinetobacter baumannii MurF Biochem.Biophys.Res.Commun., 450, 2014
2AM2	sp protein ligand 2 Descriptor: 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein Authors: Longenecker, K.L, Stamper, G.F, Hajduk, P.J, Fry, E.H, Jakob, C.G, Harlan, J.E, Edalji, R, Bartley, D.M, Walter, K.A, Solomon, L.R. Deposit date: 2005-08-08 Release date: 2006-01-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Protein Sci., 14, 2005
2AM1	sp protein ligand 1 Descriptor: 2,4-DICHLORO-N-(3-CYANO-4,5,6,7-TETRAHYDRO-BENZOTHIOPHEN-2YL)-5-(MORPHOLINE-4-SULFONYL)-BENZAMIDE, GLYCEROL, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, ... Authors: Longenecker, K.L, Stamper, G.F, Hajduk, P.J, Fry, E.H, Jakob, C.G, Harlan, J.E, Edalji, R, Bartley, D.M, Walter, K.A, Solomon, L.R. Deposit date: 2005-08-08 Release date: 2006-01-24 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Protein Sci., 14, 2005
3ZM6	CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR Descriptor: N-(6-(4-(2h-tetrazol-5-yl)benzyl)-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2,4-dichloro-5-(morpholinosulfonyl)benzamide, UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE Authors: Hrast, M, Turk, S, Sosic, I, Knez, D, Randall, C.P, Barreteau, H, Contreras-Martel, C, Dessen, A, ONeill, A.J, Mengin-Lecreulx, D, Blanot, D, Gobec, S. Deposit date: 2013-02-05 Release date: 2013-07-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf. Eur.J.Med.Chem., 66C, 2013
3ZL8	CRYSTAL STRUCTURE OF MURF LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE Authors: Favini-Stabile, S, Contreras-Martel, C, Thielens, N, Dessen, A. Deposit date: 2013-01-29 Release date: 2013-09-11 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Mreb and Murg as Scaffolds for the Cytoplasmic Steps of Peptidoglycan Biosynthesis Environ.Microbiol., 15, 2013
3ZM5	CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR Descriptor: 2,4-bis(chloranyl)-N-[3-cyano-6-[(4-hydroxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]-5-morpholin-4-ylsulfonyl-benzamide, UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE Authors: Hrast, M, Turk, S, Sosic, I, Knez, D, Randall, C.P, Barreteau, H, Contreras-Martel, C, Dessen, A, ONeill, A.J, Mengin-Lecreulx, D, Blanot, D, Gobec, S. Deposit date: 2013-02-05 Release date: 2013-07-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.94 Å) Cite: Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf. Eur.J.Med.Chem., 66C, 2013
2F00	Escherichia coli MurC Descriptor: MAGNESIUM ION, UDP-N-acetylmuramate--L-alanine ligase Authors: Deva, T, Baker, E.N, Squire, C.J, Smith, C.A. Deposit date: 2005-11-10 Release date: 2006-10-24 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of Escherichia coliUDP-N-acetylmuramoyl:L-alanine ligase (MurC). Acta Crystallogr.,Sect.D, 62, 2006
1E8C	Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli Descriptor: 2,6-DIAMINOPIMELIC ACID, CHLORIDE ION, UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ... Authors: Gordon, E.J, Chantala, L, Dideberg, O. Deposit date: 2000-09-19 Release date: 2001-09-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Udp-N-Acetylmuramoyl-L-Alanyl-D-Glutamate: Meso-Diaminopimelate Ligase from Escherichia Coli J.Biol.Chem., 276, 2001
1GG4	CRYSTAL STRUCTURE OF ESCHERICHIA COLI UDPMURNAC-TRIPEPTIDE D-ALANYL-D-ALANINE-ADDING ENZYME (MURF) AT 2.3 ANGSTROM RESOLUTION Descriptor: UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2,6-DIAMINOPIMELATE-D-ALANYL-D-ALANYL LIGASE Authors: Yan, Y, Munshi, S, Chen, Z. Deposit date: 2000-07-12 Release date: 2000-12-20 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution. J.Mol.Biol., 304, 2000
1GQQ	MURC - Crystal structure of the apo-enzyme from Haemophilus influenzae Descriptor: UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE Authors: Skarzynski, T, Cleasby, A, Domenici, E, Gevi, M, Shaw, J. Deposit date: 2001-12-03 Release date: 2003-06-15 Last modified: 2018-02-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structures of Udp-N-Acetylmuramate-L-Alanine Ligase (Murc) from Haemophilus Influenzae To be Published

 

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