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1W63
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AP1 clathrin adaptor core
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ...
Authors:Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C.
Deposit date:2004-08-12
Release date:2004-09-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
2BP5
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Descriptor: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4
Authors:Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D.
Deposit date:2005-04-18
Release date:2005-07-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
2HF6
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Solution structure of human zeta-COP
Descriptor: Coatomer subunit zeta-1
Authors:Yu, W, Jin, C, Xia, B.
Deposit date:2006-06-23
Release date:2007-06-12
Last modified:2011-11-30
Method:SOLUTION NMR
Cite:Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats
J.Mol.Biol., 386, 2009
2VGL
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AP2 CLATHRIN ADAPTOR CORE
Descriptor: ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
Authors:Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R.
Deposit date:2007-11-14
Release date:2007-12-25
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
2JKR
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AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKT
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AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2XA7
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BU of 2xa7 by Molmil
AP2 clathrin adaptor core in active complex with cargo peptides
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
Authors:Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J.
Deposit date:2010-03-29
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
3TJZ
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Crystal Structure of Arf1 Bound to the gamma/zeta-COP Core Complex
Descriptor: ADP-ribosylation factor 1, Coatomer subunit gamma, Coatomer subunit zeta-1, ...
Authors:Goldberg, J, Yu, X, Breitman, M.
Deposit date:2011-08-25
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structure-based mechanism for arf1-dependent recruitment of coatomer to membranes.
Cell(Cambridge,Mass.), 148, 2012
4HMY
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Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H.
Deposit date:2012-10-18
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
4NEE
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BU of 4nee by Molmil
crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef
Authors:Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y.
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8841 Å)
Cite:How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
4P6Z
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Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 Vpu cytoplasmic domain bound to the clathrin adaptor protein complex 1 (AP1) core
Descriptor: AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, AP-1 complex subunit mu-1, ...
Authors:Jia, X, Xiong, Y.
Deposit date:2014-03-25
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.
Elife, 3, 2014
4UQI
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BU of 4uqi by Molmil
AP2 controls clathrin polymerization with a membrane-activated switch
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ...
Authors:Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J.
Deposit date:2014-06-23
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
5A1U
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BU of 5a1u by Molmil
The structure of the COPI coat triad
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1Y
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BU of 5a1y by Molmil
The structure of the COPI coat linkage IV
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1V
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The structure of the COPI coat linkage I
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1W
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BU of 5a1w by Molmil
The structure of the COPI coat linkage II
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1X
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BU of 5a1x by Molmil
The structure of the COPI coat linkage III
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5FPI
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BU of 5fpi by Molmil
Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE
Descriptor: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J, Evans, P.R, Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016
5MC7
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BU of 5mc7 by Molmil
Crystal structure of Truncated Human Coatomer Protein Complex, subunit Z1 (CopZ1)
Descriptor: Coatomer subunit zeta-1
Authors:Lunev, S, Groves, M.R.
Deposit date:2016-11-09
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of truncated human coatomer protein complex subunit zeta 1 (Cop zeta 1).
Acta Crystallogr F Struct Biol Commun, 73, 2017
5MU7
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BU of 5mu7 by Molmil
Crystal Structure of the beta/delta-COPI Core Complex
Descriptor: Coatomer subunit beta, Coatomer subunit delta-like protein
Authors:Kopp, J, Aderhold, P, Wieland, F, Sinning, I.
Deposit date:2017-01-12
Release date:2017-06-28
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZS
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BU of 5nzs by Molmil
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
Descriptor: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZR
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BU of 5nzr by Molmil
The structure of the COPI coat leaf
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZU
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The structure of the COPI coat linkage II
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (15 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZT
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BU of 5nzt by Molmil
The structure of the COPI coat linkage I
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (17 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZV
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The structure of the COPI coat linkage IV
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (17.299999 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017

 

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