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8AYR
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BU of 8ayr by Molmil
Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota
Descriptor: CALCIUM ION, Coagulation factor 5/8 type domain protein
Authors:Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P.
Deposit date:2022-09-02
Release date:2023-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023
7XSH
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BU of 7xsh by Molmil
Crystal structure of ClAgl29B bound with L-glucose
Descriptor: Alpha-L-fucosidase, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
Deposit date:2022-05-14
Release date:2023-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.708 Å)
Cite:Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
7XSF
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BU of 7xsf by Molmil
Crystal structure of ClAgl29A
Descriptor: Alpha-L-fucosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
Deposit date:2022-05-14
Release date:2023-01-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
7XSG
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BU of 7xsg by Molmil
Crystal structure of ClAgl29B
Descriptor: Alpha-L-fucosidase, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
Deposit date:2022-05-14
Release date:2023-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.609 Å)
Cite:Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
7SNK
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BU of 7snk by Molmil
Structure of Bacple_01702, a GH29 family glycoside hydrolase
Descriptor: Alpha-L-fucosidase, PHOSPHATE ION, POTASSIUM ION
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2021-10-28
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
7PM4
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BU of 7pm4 by Molmil
Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis.
Descriptor: (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Tissue alpha-L-fucosidase
Authors:Armstrong, Z, Meek, R.W, Wu, L, Blaza, J.N, Davies, G.J.
Deposit date:2021-09-01
Release date:2022-08-10
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis.
Structure, 30, 2022
7PLS
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BU of 7pls by Molmil
Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tissue alpha-L-fucosidase
Authors:Armstrong, Z, Meek, R.W, Wu, L, Blaza, J.N, Davies, G.J.
Deposit date:2021-09-01
Release date:2022-08-10
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis.
Structure, 30, 2022
7LJJ
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BU of 7ljj by Molmil
Structure of the Exo-alpha-L-galactosidase BpGH29 from Bacteroides plebeius
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Exo-alpha-L-galactosidase
Authors:Robb, C.S, Boraston, A.B.
Deposit date:2021-01-29
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LK7
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BU of 7lk7 by Molmil
Structure of the Exo-alpha-L-galactosidase BpGH29 from Bacteroides plebeius in complex with L-galactose
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Exo-alpha-L-galactosidase, ...
Authors:Boraston, A.B, Robb, C.S.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LNP
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BU of 7lnp by Molmil
Structure of the exo-alpha-L-galactosidase BpGH29 (D264N mutant) from Bacteroides plebeius in complex with paranitrophenyl-alpha-L-galactopyranoside
Descriptor: CALCIUM ION, CHLORIDE ION, Exo-alpha-L-galactosidase, ...
Authors:Boraston, A.B, Robb, C.S.
Deposit date:2021-02-08
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
6TR3
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BU of 6tr3 by Molmil
Ruminococcus gnavus GH29 fucosidase E1_10125 in complex with fucose
Descriptor: CALCIUM ION, F5/8 type C domain-containing protein, MAGNESIUM ION, ...
Authors:Owen, C.D, Wu, H, Crost, E, Colvile, A, Juge, N, Walsh, M.A.
Deposit date:2019-12-17
Release date:2020-10-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fucosidases from the human gut symbiont Ruminococcus gnavus.
Cell.Mol.Life Sci., 78, 2021
6TR4
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BU of 6tr4 by Molmil
Ruminococcus gnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose
Descriptor: CALCIUM ION, CHLORIDE ION, F5/8 type C domain-containing protein, ...
Authors:Owen, C.D, Wu, H, Crost, E, Colvile, A, Juge, N, Walsh, M.A.
Deposit date:2019-12-17
Release date:2020-10-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Fucosidases from the human gut symbiont Ruminococcus gnavus.
Cell.Mol.Life Sci., 78, 2021
6OHE
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BU of 6ohe by Molmil
Alpha-L-fucosidase AlfC D200A in complex with Fuca(1,6)GlcNAc
Descriptor: AlfC, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-04-05
Release date:2020-04-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O1J
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BU of 6o1j by Molmil
Alpha-L-fucosidase AlfC fucosyltransferase mutant N243A
Descriptor: AlfC, beta-L-fucopyranose
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-20
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O1I
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BU of 6o1i by Molmil
Alpha-L-fucosidase AlfC fucosyltransferase mutant E274A
Descriptor: AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-20
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O1C
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BU of 6o1c by Molmil
Alpha-L-fucosidase AlfC D200A mutant in complex with 4-nitrophenyl-a-L-fucopyranoside substrate
Descriptor: 4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside, AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-19
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O1A
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BU of 6o1a by Molmil
Alpha-L-fucosidase AlfC from Lactobacillus casei in complex with alpha-L-fucose product
Descriptor: AlfC, beta-L-fucopyranose
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O18
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BU of 6o18 by Molmil
Unliganded alpha-L-fucosidase AlfC from Lactobacillus casei
Descriptor: AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6ORH
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BU of 6orh by Molmil
Crystal structure of SpGH29
Descriptor: 1,2-ETHANEDIOL, Glycoside hydrolase, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 294, 2019
6ORG
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BU of 6org by Molmil
Crystal structure of SpGH29
Descriptor: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 294, 2019
6ORF
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BU of 6orf by Molmil
Crystal structure of SpGH29
Descriptor: 1,2-ETHANEDIOL, SpGH29, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 294, 2019
6OR4
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BU of 6or4 by Molmil
Crystal structure of SpGH29
Descriptor: Glycoside hydrolase, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2019-04-29
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 294, 2019
6HZY
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BU of 6hzy by Molmil
Crystal structure of a bacterial fucosidase with inhibitor FucPUG
Descriptor: 1,2-ETHANEDIOL, Alpha-L-fucosidase, SULFATE ION, ...
Authors:Wu, L, Davies, G.J, Stubbs, K.A, Coyle, T, Debowski, A.W.
Deposit date:2018-10-24
Release date:2019-02-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors.
Chembiochem, 20, 2019
6GN6
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BU of 6gn6 by Molmil
Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus
Descriptor: Alpha-L-fucosidase, DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ...
Authors:Kovalova, T, Koval, T, Lipovova, P, Dohnalek, J.
Deposit date:2018-05-30
Release date:2018-12-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Active site complementation and hexameric arrangement in the GH family 29; a structure-function study of alpha-l-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus.
Glycobiology, 29, 2019
5K9H
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BU of 5k9h by Molmil
Crystal structure of a glycoside hydrolase 29 family member from an unknown rumen bacterium
Descriptor: 0940_GH29, GLYCEROL, SODIUM ION, ...
Authors:Summers, E.L, Arcus, V.L.
Deposit date:2016-05-31
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.029 Å)
Cite:The structure of a glycoside hydrolase 29 family member from a rumen bacterium reveals unique, dual carbohydrate-binding domains.
Acta Crystallogr.,Sect.F, 72, 2016

 

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