5A63
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CRYO-EM STRUCTURE OF THE HUMAN GAMMA-SECRETASE COMPLEX AT 3.4 ANGSTROM RESOLUTION.
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X., Yan, C., Yang, G., Lu, P., Ma, D., Sun, L., Zhou, R., Scheres, S.H.W., Shi, Y.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
5FN2
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A DRUG DAPT
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN3
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 1 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 2 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN5
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 3 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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