1S4G
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SOMATOMEDIN-B DOMAIN OF HUMAN PLASMA VITRONECTIN.
Descriptor:Vitronectin, HYDROXIDE ION
Authors:Mayasundari, A., Whittemore, N.A., Serpersu, E.H., Peterson, C.B.
Deposit date:2004-01-16
Release date:2004-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal domain of human vitronectin: proximal sites that regulate fibrinolysis and cell migration
J.Biol.Chem., 279, 2004
1SSU
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR DISULFIDE BOND HETEROGENEITY IN ACTIVE FORMS OF THE SOMATOMEDIN B DOMAIN OF HUMAN VITRONECTIN
Descriptor:Vitronectin
Authors:Kamikubo, Y., De Guzman, R., Kroon, G., Curriden, S., Neels, J.G., Churchill, M.J., Dawson, P., Oldziej, S., Jagielska, A., Scheraga, H.A., Loskutoff, D.J., Dyson, H.J.
Deposit date:2004-03-24
Release date:2004-07-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin.
Biochemistry, 43, 2004
2CQW
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SOLUTION STRUCTURE OF RSGI RUH-041, A SMB-LIKE DOMAIN FROM MOUSE CDNA
Descriptor:Sushi domain containing 2
Authors:Hamada, T., Hirota, H., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of RSGI RUH-041, a SMB-like domain from mouse cDNA
To be Published
2JQ8
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SOLUTION STRUCTURE OF THE SOMATOMEDIN B DOMAIN FROM VITRONECTIN PRODUCED IN PICHIA PASTORIS
Descriptor:Vitronectin
Authors:Gaardsvoll, H., Hirschberg, D., Nielbo, S., Mayasundari, A., Peterson, C.B., Jansson, A., Jorgensen, T.J.D., Poulsen, F.M.
Deposit date:2007-05-30
Release date:2007-09-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris
Protein Sci., 16, 2007
2YS0
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SOLUTION STRUCTURE OF THE SOMATOMEDIN B DOMAIN OF HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Authors:Abe, H., Sasagawa, A., Tochio, N., Tomizawa, T., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2007-10-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Somatomedin B domain of human Ectonucleotide pyrophosphatase/phosphodiesterase family member
To be Published
2XR9
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CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2)
Descriptor:ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kamtekar, S., Hausmann, J., Day, J.E., Christodoulou, E., Perrakis, A.
Deposit date:2010-09-13
Release date:2011-01-19
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of substrate discrimination and integrin binding by autotaxin.
Nat. Struct. Mol. Biol., 18, 2011
2XRG
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CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) IN COMPLEX WITH THE HA155 BORONIC ACID INHIBITOR
Descriptor:ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Hausmann, J., Albers, H.M.H.G., Perrakis, A.
Deposit date:2010-09-14
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis of Substrate Discrimination and Integrin Binding by Autotaxin.
Nat.Struct.Mol.Biol., 18, 2011
3NKM
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 14:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKO
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 16:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:1-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:3-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 22:6-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.704 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3WAV
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH COMPOUND 10
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
3WAW
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 2BOA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
3WAX
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 3BOA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
3WAY
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 4BOA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.746 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
4B56
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STRUCTURE OF ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (NPP1)
Descriptor:ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 1, ZINC ION, CALCIUM ION, ...
Authors:Jansen, S., Perrakis, A., Ulens, C., Winkler, C., Andries, M., Joosten, R.P., Van Acker, M., Luyten, F.P., Moolenaar, W.H., Bollen, M.
Deposit date:2012-08-02
Release date:2012-09-19
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Npp1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification.
Structure, 20, 2012
4GTW
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH AMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTX
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH TMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTY
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH GMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTZ
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH CMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.191 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ZG6
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STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Stein, A.J., Bain, G., Hutchinson, J.H., Evans, J.F.
Deposit date:2015-04-22
Release date:2015-10-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Mol.Pharmacol., 88, 2015
4ZG7
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STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Stein, A.J., Bain, G., Hutchinson, J.H., Evans, J.F.
Deposit date:2015-04-22
Release date:2015-10-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Mol.Pharmacol., 88, 2015
4ZG9
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STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Stein, A.J., Bain, G., Hutchinson, J.H., Evans, J.F.
Deposit date:2015-04-22
Release date:2015-10-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Mol.Pharmacol., 88, 2015
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