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8OIW
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BU of 8oiw by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under oxidising conditions (space group P 21 21 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-23
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
8OIH
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BU of 8oih by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under oxidising conditions (space group C 2 2 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, BROMIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-22
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
8OH8
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BU of 8oh8 by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group P 21 21 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-20
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
8OFK
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BU of 8ofk by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group C 2 2 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-15
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.713 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
7QAR
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BU of 7qar by Molmil
Serial crystallography structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-methyl uric acid at room temperature
Descriptor: (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, Uricase
Authors:Bui, S, Catapano, L, Zielinski, K, Yefanov, O, Murshudov, G.N, Oberthuer, D, Steiner, R.A.
Deposit date:2021-11-17
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive.
Iucrj, 9, 2022
7Q09
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BU of 7q09 by Molmil
URATE OXIDASE AZA-XANTHINE COMPLEX UNDER 1500 BAR OF ARGON
Descriptor: 8-AZAXANTHINE, ACETYL GROUP, ARGON, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2021-10-14
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7PWN
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BU of 7pwn by Molmil
URATE OXYDASE AZA-XANTHINE COMPLEX AT 1000 BARS (100 MPa) OF ARGON
Descriptor: 8-AZAXANTHINE, ARGON, SODIUM ION, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2021-10-07
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7PUF
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BU of 7puf by Molmil
urate oxidase azaxanthine complex under 600 bar (60 MPa) of argon
Descriptor: 8-AZAXANTHINE, ARGON, SODIUM ION, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2021-09-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7P0G
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BU of 7p0g by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER AMBIENT PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7P0D
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BU of 7p0d by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER 310 MPA PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7P0C
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BU of 7p0c by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER 210 MPA PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7F2W
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BU of 7f2w by Molmil
TbUox in complex with uric acid
Descriptor: URIC ACID, Uricase
Authors:Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H.
Deposit date:2021-06-14
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy.
Int.J.Biol.Macromol., 188, 2021
7F2V
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BU of 7f2v by Molmil
Urate oxidase from Thermobispora bispora in apo form
Descriptor: DIMETHYL SULFOXIDE, SULFATE ION, Uricase
Authors:Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H.
Deposit date:2021-06-14
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy.
Int.J.Biol.Macromol., 188, 2021
7CUG
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BU of 7cug by Molmil
Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride Anion at 1.62 A resolution
Descriptor: 2-METHOXYETHANOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
Authors:Hibi, T, Itoh, T.
Deposit date:2020-08-23
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification of quasi-stable water molecules near the Thr73-Lys13 catalytic diad of Bacillus sp. TB-90 urate oxidase by X-ray crystallography with controlled humidity.
J.Biochem., 169, 2021
7CUF
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BU of 7cuf by Molmil
Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride Anion at 1.44 A resolution
Descriptor: 2-METHOXYETHANOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
Authors:Hibi, T, Itoh, T.
Deposit date:2020-08-22
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Identification of quasi-stable water molecules near the Thr73-Lys13 catalytic diad of Bacillus sp. TB-90 urate oxidase by X-ray crystallography with controlled humidity.
J.Biochem., 169, 2021
7CUC
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BU of 7cuc by Molmil
Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride Anion at 1.44 A resolution
Descriptor: 2-METHOXYETHANOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
Authors:Hibi, T, Itoh, T.
Deposit date:2020-08-22
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Identification of quasi-stable water molecules near the Thr73-Lys13 catalytic diad of Bacillus sp. TB-90 urate oxidase by X-ray crystallography with controlled humidity.
J.Biochem., 169, 2021
7CMQ
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BU of 7cmq by Molmil
Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88% RH.
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
Authors:Hibi, T, Itoh, T, Nishiya, Y.
Deposit date:2020-07-28
Release date:2020-08-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Flexibility of a Distal Interface Loop Modulates Water Network in the Active Site of Bacillus sp. TB-90 Urate Oxidase
To be published
7CMN
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BU of 7cmn by Molmil
Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88% RH.
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
Authors:Hibi, T, Itoh, T, Nishiya, Y.
Deposit date:2020-07-28
Release date:2020-08-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Flexibility of a Distal Interface Loop Modulates Water Network in the Active Site of Bacillus sp. TB-90 Urate Oxidase
To be published
7A0L
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BU of 7a0l by Molmil
Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A.
Deposit date:2020-08-09
Release date:2020-12-09
Last modified:2021-02-10
Method:NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION
Cite:Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis.
Iucrj, 8, 2021
6RGT
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BU of 6rgt by Molmil
Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-METHYL URIC ACID, ...
Authors:Bui, S, Lowden, S.R.J, Steiner, R.A.
Deposit date:2019-04-17
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid
To Be Published
6RGM
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BU of 6rgm by Molmil
urate oxidase under 130 bar of krypton
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2019-04-17
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
6OE8
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BU of 6oe8 by Molmil
The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C
Descriptor: MALONATE ION, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
Authors:Shi, Y, Wang, T, Zhou, X.E, Liu, Q, Jiang, Y, Xu, H.E.
Deposit date:2019-03-27
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy.
Acta Pharmacol.Sin., 40, 2019
6IC1
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BU of 6ic1 by Molmil
urate oxidase under 90 bar of krypton
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2018-12-01
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
6IA9
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BU of 6ia9 by Molmil
urate oxidase under 2000 bar (220 MPa) of argon
Descriptor: 8-AZAXANTHINE, ACETYL GROUP, ARGON, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2018-11-26
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
6IA3
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BU of 6ia3 by Molmil
urate oxidase under 220 bar (22 MPa) of argon
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ARGON, ...
Authors:Prange, T, Colloc'h, N, Carpentier, P.
Deposit date:2018-11-26
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022

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PDB entries from 2024-03-27

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