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2QKS
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BU of 2qks by Molmil
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera
Descriptor: Kir3.1-prokaryotic Kir channel chimera, POTASSIUM ION, nonyl beta-D-glucopyranoside
Authors:Nishida, M, MacKinnon, R.
Deposit date:2007-07-11
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a Kir3.1-prokaryotic Kir channel chimera.
Embo J., 26, 2007
5KUK
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BU of 5kuk by Molmil
Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant
Descriptor: ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION
Authors:Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G.
Deposit date:2016-07-13
Release date:2016-08-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
5KUM
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BU of 5kum by Molmil
Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2
Descriptor: ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION, ...
Authors:Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G.
Deposit date:2016-07-13
Release date:2016-08-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
8I5M
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BU of 8i5m by Molmil
Rat Kir4.1 in complex with PIP2
Descriptor: ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Zhao, C, Guo, J.
Deposit date:2023-01-26
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses
To Be Published
8I5N
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Rat Kir4.1 in complex with PIP2 and Lys05
Descriptor: ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Zhao, C, Guo, J.
Deposit date:2023-01-26
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses
To Be Published
3K6N
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BU of 3k6n by Molmil
Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain
Descriptor: G protein-activated inward rectifier potassium channel 1, SODIUM ION
Authors:Xu, Y, Shin, H.G, Szep, S, Lu, Z.
Deposit date:2009-10-09
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Physical determinants of strong voltage sensitivity of K(+) channel block.
Nat.Struct.Mol.Biol., 16, 2009
3JYC
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BU of 3jyc by Molmil
Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 Angstrom resolution
Descriptor: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
Authors:Tao, X.
Deposit date:2009-09-21
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution.
Science, 326, 2009
6M84
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BU of 6m84 by Molmil
Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2
Descriptor: ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ...
Authors:Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G.
Deposit date:2018-08-21
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
J.Gen.Physiol., 152, 2020
6M85
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BU of 6m85 by Molmil
Crystal Structure of Inward Rectifier Kir2.2 in a different salt condition
Descriptor: ATP-sensitive inward rectifier potassium channel 12, POTASSIUM ION
Authors:Lee, S.-J, Nichols, C.G.
Deposit date:2018-08-21
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
J.Gen.Physiol., 152, 2020
6M86
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BU of 6m86 by Molmil
Crystal Structure of Inward Rectifier Kir2.2 Force Open Mutant
Descriptor: ATP-sensitive inward rectifier potassium channel 12, POTASSIUM ION
Authors:Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G.
Deposit date:2018-08-21
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Potassium conduction through an eukarytoic inwardly rectifying potassium channel
To be published
6XIS
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BU of 6xis by Molmil
Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in apo form
Descriptor: G protein-activated inward rectifier potassium channel 2
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2020-06-21
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.
Elife, 9, 2020
6XIT
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BU of 6xit by Molmil
Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with PIP2
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2020-06-21
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.
Elife, 9, 2020
6XEV
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BU of 6xev by Molmil
CryoEM structure of GIRK2-PIP2/CHS - G protein-gated inwardly rectifying potassium channel GIRK2 with modulators cholesteryl hemisuccinate and PIP2
Descriptor: CHOLESTEROL HEMISUCCINATE, G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, ...
Authors:Mathiharan, Y.K, Glaaser, I.W, Skiniotis, G, Slesinger, P.A.
Deposit date:2020-06-14
Release date:2021-09-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into GIRK2 channel modulation by cholesterol and PIP2
Cell Rep, 36, 2021
6XEU
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BU of 6xeu by Molmil
CryoEM structure of GIRK2PIP2* - G protein-gated inwardly rectifying potassium channel GIRK2 with PIP2
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION, ...
Authors:Mathiharan, Y.K, Glaaser, I.W, Skiniotis, G, Slesinger, P.A.
Deposit date:2020-06-13
Release date:2021-09-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into GIRK2 channel modulation by cholesterol and PIP2
Cell Rep, 36, 2021
7S5T
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BU of 7s5t by Molmil
Human KATP channel in open conformation, focused on Kir (C166S G334D double mutant) and SUR TMD0
Descriptor: ATP-sensitive inward rectifier potassium channel 11, POTASSIUM ION
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
3SPI
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BU of 3spi by Molmil
Inward rectifier potassium channel Kir2.2 in complex with PIP2
Descriptor: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Hansen, S.B, Tao, X, MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.307 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SYA
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BU of 3sya by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium and PIP2
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION, ...
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2011-07-16
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3SPH
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BU of 3sph by Molmil
Inward rectifier potassium channel Kir2.2 I223L mutant in complex with PIP2
Descriptor: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Hansen, S.B, Tao, X, MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SYC
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BU of 3syc by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) D228N mutant
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2011-07-16
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3SPG
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BU of 3spg by Molmil
Inward rectifier potassium channel Kir2.2 R186A mutant in complex with PIP2
Descriptor: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Hansen, S.B, Tao, X, MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.613 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SPC
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BU of 3spc by Molmil
Inward rectifier potassium channel Kir2.2 in complex with dioctanoylglycerol pyrophosphate (DGPP)
Descriptor: (2R)-3-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}propane-1,2-diyl dioctanoate, Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
Authors:Hansen, S.B, Tao, X, MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.454 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SYP
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BU of 3syp by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2011-07-18
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3SYO
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BU of 3syo by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2011-07-18
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3SPJ
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BU of 3spj by Molmil
Apo inward rectifier potassium channel Kir2.2 I223L mutant
Descriptor: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
Authors:Hansen, S.B, Tao, X, MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.307 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SYQ
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BU of 3syq by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant in complex with PIP2
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2011-07-18
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011

 

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