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1W25
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BU of 1w25 by Molmil
Response regulator PleD in complex with c-diGMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, STALKED-CELL DIFFERENTIATION CONTROLLING PROTEIN, ...
Authors:Chan, C, Schirmer, T, Jenal, U.
Deposit date:2004-06-28
Release date:2004-11-18
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Activity and Allosteric Control of Diguanylate Cyclase
Proc.Natl.Acad.Sci.USA, 101, 2004
2V0N
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BU of 2v0n by Molmil
ACTIVATED RESPONSE REGULATOR PLED IN COMPLEX WITH C-DIGMP AND GTP- ALPHA-S
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
Authors:Wassmann, P, Schirmer, T.
Deposit date:2007-05-15
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structure of Bef3--Modified Response Regulator Pled: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
Structure, 15, 2007
2WB4
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BU of 2wb4 by Molmil
activated diguanylate cyclase PleD in complex with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, DIGUANYLATE CYCLASE, ...
Authors:Wassmann, P, Schirmer, T.
Deposit date:2009-02-20
Release date:2010-04-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms
To be Published
3BRE
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BU of 3bre by Molmil
Crystal Structure of P.aeruginosa PA3702
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Probable two-component response regulator
Authors:De, N, Pirruccello, M, Krasteva, P.V, Bae, N, Raghavan, R.V, Sondermann, H.
Deposit date:2007-12-21
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Phosphorylation-independent regulation of the diguanylate cyclase WspR.
Plos Biol., 6, 2008
3EZU
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BU of 3ezu by Molmil
Crystal structure of multidomain protein of unknown function with GGDEF-domain (NP_951600.1) from GEOBACTER SULFURREDUCENS at 1.95 A resolution
Descriptor: 1,2-ETHANEDIOL, GGDEF domain protein, UNKNOWN LIGAND
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-23
Release date:2008-11-18
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of multidomain protein of unknown function with GGDEF-domain (NP_951600.1) from GEOBACTER SULFURREDUCENS at 1.95 A resolution
To be published
3HVA
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BU of 3hva by Molmil
Crystal structure of FimX GGDEF domain from Pseudomonas aeruginosa
Descriptor: Protein FimX
Authors:Navarro, M.V.A.S, De, N, Bae, N, Sondermann, H.
Deposit date:2009-06-15
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
3HVW
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BU of 3hvw by Molmil
Crystal Structure of the GGDEF domain of the PA2567 protein from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaR365C
Descriptor: Diguanylate-cyclase (DGC)
Authors:Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-16
Release date:2009-06-23
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Northeast Structural Genomics Consortium Target PaR365C
To be published
3I5A
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BU of 3i5a by Molmil
Crystal structure of full-length WpsR from Pseudomonas syringae
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Response regulator/GGDEF domain protein, STRONTIUM ION
Authors:Navarro, M.V.A.S, De, N, Sondermann, H.
Deposit date:2009-07-03
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
J.Mol.Biol., 393, 2009
3I5B
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BU of 3i5b by Molmil
Crystal structure of the isolated GGDEF domain of WpsR from Pseudomonas aeruginosa
Descriptor: L(+)-TARTARIC ACID, WspR response regulator
Authors:Navarro, M.V.A.S, De, N, Sondermann, H.
Deposit date:2009-07-03
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
J.Mol.Biol., 393, 2009
3I5C
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BU of 3i5c by Molmil
Crystal structure of a fusion protein containing the leucine zipper of GCN4 and the GGDEF domain of WspR from Pseudomonas aeruginosa
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Fusion of General control protein GCN4 and WSPR response regulator protein, MAGNESIUM ION
Authors:Navarro, M.V.A.S, De, N, Sondermann, H.
Deposit date:2009-07-03
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
J.Mol.Biol., 393, 2009
3ICL
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BU of 3icl by Molmil
X-Ray Structure of Protein (EAL/GGDEF domain protein) from M.capsulatus, Northeast Structural Genomics Consortium Target McR174C
Descriptor: EAL/GGDEF domain protein, SULFATE ION
Authors:Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-07-17
Release date:2009-08-04
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Northeast Structural Genomics Consortium Target McR174C
To be Published
3IGN
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BU of 3ign by Molmil
Crystal Structure of the GGDEF domain from Marinobacter aquaeolei diguanylate cyclase complexed with c-di-GMP - Northeast Structural Genomics Consortium Target MqR89a
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate cyclase
Authors:Vorobiev, S, Neely, H, Seetharaman, J, Wang, H, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-07-28
Release date:2009-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product.
J.Struct.Funct.Genom., 13, 2012
3MTK
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BU of 3mtk by Molmil
X-Ray Structure of Diguanylate cyclase/phosphodiesterase from Caldicellulosiruptor saccharolyticus, Northeast Structural Genomics Consortium Target ClR27C
Descriptor: Diguanylate cyclase/phosphodiesterase
Authors:Kuzin, A, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-30
Release date:2010-06-02
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Northeast Structural Genomics Consortium Target ClR27C
To be Published
3PJW
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BU of 3pjw by Molmil
Structure of Pseudomonas fluorescence LapD GGDEF-EAL dual domain, I23
Descriptor: Cyclic dimeric GMP binding protein
Authors:Sondermann, H, Navarro, M.V.A.S.
Deposit date:2010-11-10
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1006 Å)
Cite:Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis.
Plos Biol., 9, 2011
3PJX
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BU of 3pjx by Molmil
Structure of Pseudomonas fluorescence LapD GGDEF-EAL dual domain, P32
Descriptor: 1,2-ETHANEDIOL, Cyclic dimeric GMP binding protein
Authors:Sondermann, H, Navarro, M.V.A.S.
Deposit date:2010-11-10
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.0002 Å)
Cite:Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis.
Plos Biol., 9, 2011
3QYY
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BU of 3qyy by Molmil
A Novel Interaction Mode between a Microbial GGDEF Domain and the Bis-(3, 5 )-cyclic di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Yang, C.-Y, Chin, K.-H, Chou, S.-H.
Deposit date:2011-03-04
Release date:2011-11-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)(2) at the active site
Acta Crystallogr.,Sect.D, 67, 2011
3TVK
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BU of 3tvk by Molmil
Diguanylate cyclase domain of DgcZ
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), D(-)-TARTARIC ACID, Diguanylate cyclase DgcZ, ...
Authors:Zaehringer, F, Schirmer, T.
Deposit date:2011-09-20
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
Structure, 21, 2013
4H54
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BU of 4h54 by Molmil
Crystal structure of the diguanylate cyclase DgcZ
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate cyclase YdeH, GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, ...
Authors:Zaehringer, F, Schirmer, T.
Deposit date:2012-09-18
Release date:2013-07-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
Structure, 21, 2013
4IOB
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BU of 4iob by Molmil
Crystal structure of the GGDEF domain of PA1120 (YfiN or TpbB) from Pseudomonas aeruginosa at 2.7 Ang.
Descriptor: Diguanylate cyclase TpbB, GLYCEROL, TERTIARY-BUTYL ALCOHOL
Authors:Giardina, G, Cutruzzola, F.
Deposit date:2013-01-07
Release date:2013-12-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain.
Plos One, 8, 2013
4J40
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BU of 4j40 by Molmil
Crystal structure of the dual-domain GGDEF-EAL module of FimX from Pseudomonas aeruginosa
Descriptor: FimX
Authors:Navarro, M.V, De, N, Bae, N, Wang, Q, Sondermann, H.
Deposit date:2013-02-06
Release date:2013-02-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
Structure, 17, 2009
4RNF
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BU of 4rnf by Molmil
PaMorA tandem diguanylate cyclase - mutant phosphodiesterase, apo form
Descriptor: Motility regulator
Authors:Phippen, C.W, Tews, I.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNH
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BU of 4rnh by Molmil
PaMorA tandem diguanylate cyclase - phosphodiesterase, c-di-GMP complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Motility regulator
Authors:Phippen, C.W, Tews, I.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4URG
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BU of 4urg by Molmil
Crystal Structure of GGDEF domain from T.maritima (active-like dimer)
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE
Authors:Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
Deposit date:2014-06-30
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
4URQ
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BU of 4urq by Molmil
Crystal Structure of GGDEF domain (I site mutant) from T.maritima
Descriptor: DIGUANYLATE CYCLASE
Authors:Deepthi, A, Liew, C.W, Liang, Z.X, Swamianthan, K, Lescar, J.
Deposit date:2014-07-01
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
4URS
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BU of 4urs by Molmil
Crystal Structure of GGDEF domain from T.maritima
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE, ...
Authors:Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
Deposit date:2014-07-02
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014

 

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