4K6M
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CRYSTAL STRUCTURE OF THE FULL-LENGTH JAPANESE ENCEPHALITIS VIRUS NS5
Descriptor:Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Lu, G., Gong, P.
Deposit date:2013-04-16
Release date:2013-08-28
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface
Plos Pathog., 9, 2013
4V0Q
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH SAH
Descriptor:NS5 POLYMERASE, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhao, Y., Soh, S., Zheng, J., Phoo, W.W., Swaminathan, K., Cornvik, T.C., Lim, S.P., Shi, P.-Y., Lescar, J., Vasudevan, S.G., Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
4V0R
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
Descriptor:NS5 POLYMERASE, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhao, Y., Soh, S., Zheng, J., Phoo, W.W., Swaminathan, K., Cornvik, T.C., Lim, S.P., Shi, P.-Y., Lescar, J., Vasudevan, S.G., Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
5CCV
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CRYSTAL STRUCTURE OF FULL-LENGTH NS5 FROM DENGUE VIRUS TYPE 3
Descriptor:RNA-directed RNA polymerase NS5, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Klema, V.J., Choi, K.H.
Deposit date:2015-07-02
Release date:2016-02-03
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of full-length NS5 from dengue virus type 3
to be published
5DTO
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH VIRAL CAP 0-RNA AND SAH
Descriptor:NS5, RNA (5'-R(P*AP*GP*UP*U)-3'), ZINC ION, ...
Authors:Zhao, Y., Soh, T.S., Lim, S.P., Chung, K.Y., Swaminathan, K., Vasudevan, S.G., Shi, P.-Y., Lescar, J., Luo, D.
Deposit date:2015-09-18
Release date:2015-11-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
Proc.Natl.Acad.Sci.USA, 112, 2015
5JJR
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DENGUE 3 NS5 PROTEIN WITH COMPOUND 29
Descriptor:Genome polyprotein, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Lescar, J., El Sahili, A.
Deposit date:2016-04-25
Release date:2016-07-06
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
5JJS
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DENGUE 3 NS5 PROTEIN WITH COMPOUND 27
Descriptor:Genome polyprotein, ZINC ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Lescar, J., El Sahili, A.
Deposit date:2016-04-25
Release date:2016-07-06
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
5M2X
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CRYSTAL STRUCTURE OF THE FULL-LENGTH ZIKA VIRUS NS5 PROTEIN (HUMAN ISOLATE Z1106033)
Descriptor:NS5, S-ADENOSYL-L-HOMOCYSTEINE, PHOSPHATE ION, ...
Authors:Ferrero, D.S., Ruiz-Arroyo, V.M., Soler, N., Uson, I., Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Method:X-RAY DIFFRACTION (4.991 Å)
Cite:Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
To Be Published
5M2Z
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CRYSTAL STRUCTURE OF THE FULL-LENGTH ZIKA VIRUS NS5 PROTEIN (HUMAN ISOLATE Z1106033)
Descriptor:NS5, PHOSPHATE ION, ZINC ION, ...
Authors:Ferrero, D.S., Ruiz-Arroyo, V.M., Soler, N., Uson, I., Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
To Be Published
5TFR
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CRYSTAL STRUCTURE OF ZIKA VIRUS NS5 PROTEIN
Descriptor:Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Longenecker, K.L., Upadhyay, A.K.
Deposit date:2016-09-26
Release date:2016-10-12
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5TMH
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STRUCTURE OF ZIKA VIRUS NS5
Descriptor:Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
Authors:Wang, B., Tan, X., Song, J.
Deposit date:2016-10-12
Release date:2017-02-08
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.278 Å)
Cite:Structure of Zika virus NS5
To Be Published
5U0B
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STRUCTURE OF FULL-LENGTH ZIKA VIRUS NS5
Descriptor:Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
Authors:Zhao, B., Du, F.
Deposit date:2016-11-23
Release date:2017-03-29
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
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