1H6F
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HUMAN TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FOR ULNAR-MAMMARY SYNDROME, BOUND TO A PALINDROMIC DNA SITE
Descriptor:T-BOX TRANSCRIPTION FACTOR TBX3, 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION
Authors:Coll, M., Muller, C.W.
Deposit date:2001-06-13
Release date:2002-04-19
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10, 2002
1XBR
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T DOMAIN FROM XENOPUS LAEVIS BOUND TO DNA
Descriptor:DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*G P*TP*GP*AP*AP*AP* TP*T)-3'), PROTEIN (T PROTEIN)
Authors:Muller, C.W.
Deposit date:1997-07-16
Release date:1998-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
Nature, 389, 1997
2X6U
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CRYSTAL STRUCTURE OF HUMAN TBX5 IN THE DNA-FREE FORM
Descriptor:T-BOX TRANSCRIPTION FACTOR TBX5, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION
Authors:Stirnimann, C.U., Mueller, C.W.
Deposit date:2010-02-22
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
2X6V
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CRYSTAL STRUCTURE OF HUMAN TBX5 IN THE DNA-BOUND AND DNA-FREE FORM
Descriptor:T-BOX TRANSCRIPTION FACTOR TBX5, 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3', 5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3', ...
Authors:Ptchelkine, D., Stirnimann, C.U., Grimm, C., Mueller, C.W.
Deposit date:2010-02-22
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
4A04
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STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMAN TBX1, A TRANSCRIPTION FACTOR ASSOCIATED WITH THE DIGEORGE SYNDROME
Descriptor:T-BOX TRANSCRIPTION FACTOR TBX1, DNA
Authors:El Omari, K., De Mesmaeker, J., Karia, D., Ginn, H., Bhattacharya, S., Mancini, E.J.
Deposit date:2011-09-07
Release date:2011-10-12
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of the DNA-Bound T-Box Domain of Human Tbx1, a Transcription Factor Associated with the Digeorge Syndrome
Proteins, 80, 2012
4S0H
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TBX5 DB, NKX2.5 HD, ANF DNA COMPLEX
Descriptor:T-box transcription factor TBX5, Homeobox protein Nkx-2.5, 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP*TP*GP*AP*AP*GP*TP*GP*G)-3', ...
Authors:Pradhan, L.
Deposit date:2014-12-31
Release date:2015-12-16
Last modified:2016-04-13
Method:X-RAY DIFFRACTION (2.817 Å)
Cite:Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
5BQD
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CRYSTAL STRUCTURE OF TBX5 (1-239) DIMER
Descriptor:T-box transcription factor TBX5, MAGNESIUM ION
Authors:Pradhan, L., Gopal, S., Patel, A., Kasahara, H., Nam, H.J.
Deposit date:2015-05-28
Release date:2016-03-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.583 Å)
Cite:Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
5T1J
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CRYSTAL STRUCTURE OF THE TBOX DNA BINDING DOMAIN OF THE TRANSCRIPTION FACTOR T-BET
Descriptor:T-box transcription factor TBX21, DNA
Authors:Liu, C.F., Brandt, G.S., Hoang, Q., Hwang, E.S., Naumova, N., Lazarevic, V., Dekker, J., Glimcher, L.H., Ringe, D., Petsko, G.A.
Deposit date:2016-08-19
Release date:2016-10-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.947 Å)
Cite:Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.
Proc.Natl.Acad.Sci.USA, 113, 2016
6F58
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CRYSTAL STRUCTURE OF HUMAN BRACHYURY (T) IN COMPLEX WITH DNA
Descriptor:DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*TP*T)-3'), Brachyury protein, SODIUM ION
Authors:Newman, J.A., Gavard, A.E., Krojer, T., Shrestha, L., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Deposit date:2017-12-01
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Crystal structure of human Brachyury (T) in complex with DNA
To Be Published
6F59
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CRYSTAL STRUCTURE OF HUMAN BRACHYURY (T) G177D VARIANT IN COMPLEX WITH DNA
Descriptor:DNA (26-MER), Brachyury protein, SODIUM ION, ...
Authors:Newman, J.A., Gavard, A.E., Krojer, T., Shrestha, L., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Deposit date:2017-12-01
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Crystal structure of human Brachyury (T) G177D variant in complex with DNA
To Be Published
5FLV
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CRYSTAL STRUCTURE OF NKX2-5 AND TBX5 BOUND TO THE NPPA PROMOTER REGION
Descriptor:HOMEOBOX PROTEIN NKX-2.5, T-BOX TRANSCRIPTION FACTOR TBX5, 5'-D(*TP*CP*TP*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP *TP*GP*AP*AP*GP*TP*GP*G)-3', ...
Authors:Stirnimann, C.U., Glatt, S., Mueller, C.W.
Deposit date:2015-10-28
Release date:2016-02-10
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.
Cell(Cambridge,Mass.), 164, 2016
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