Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1LDJ
DownloadVisualize
BU of 1ldj by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: Cullin homolog 1, ZINC ION, ring-box protein 1
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1LDK
DownloadVisualize
BU of 1ldk by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ...
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1U6G
DownloadVisualize
BU of 1u6g by Molmil
Crystal Structure of The Cand1-Cul1-Roc1 Complex
Descriptor: Cullin homolog 1, RING-box protein 1, TIP120 protein, ...
Authors:Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N.
Deposit date:2004-07-29
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
Cell(Cambridge,Mass.), 119, 2004
2HYE
DownloadVisualize
BU of 2hye by Molmil
Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex
Descriptor: Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ...
Authors:Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N.
Deposit date:2006-08-05
Release date:2006-10-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
2WZK
DownloadVisualize
BU of 2wzk by Molmil
Structure of the Cul5 N-terminal domain at 2.05A resolution.
Descriptor: 1,2-ETHANEDIOL, CULLIN-5
Authors:Muniz, J.R.C, Ayinampudi, V, Zhang, Y, Babon, J.J, Chaikuad, A, Krojer, T, Pike, A.C.W, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A.N.
Deposit date:2009-11-30
Release date:2009-12-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
J.Mol.Biol., 425, 2013
3DPL
DownloadVisualize
BU of 3dpl by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.
Descriptor: Cullin-5, RING-box protein 1, ZINC ION
Authors:Duda, D.M, Schulman, B.A.
Deposit date:2008-07-08
Release date:2008-09-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3DQV
DownloadVisualize
BU of 3dqv by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
Descriptor: Cullin-5, NEDD8, Rbx1, ...
Authors:Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A.
Deposit date:2008-07-09
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3RTR
DownloadVisualize
BU of 3rtr by Molmil
A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A.
Deposit date:2011-05-03
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
4A0C
DownloadVisualize
BU of 4a0c by Molmil
Structure of the CAND1-CUL4B-RBX1 complex
Descriptor: CULLIN-4B, CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1, E3 UBIQUITIN-PROTEIN LIGASE RBX1, ...
Authors:Scrima, A, Fischer, E.S, Faty, M, Gut, H, Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A0K
DownloadVisualize
BU of 4a0k by Molmil
STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5.93 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0L
DownloadVisualize
BU of 4a0l by Molmil
Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex
Descriptor: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A64
DownloadVisualize
BU of 4a64 by Molmil
Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution
Descriptor: 1,2-ETHANEDIOL, CULLIN-4B
Authors:Vollmar, M, Ayinampudi, V, Cooper, C, Guo, K, Krojer, T, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Bullock, A.
Deposit date:2011-10-31
Release date:2012-02-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal Structure of the N-Terminal Domain of Human Cul4B at 2.57A Resolution
To be Published
4AP2
DownloadVisualize
BU of 4ap2 by Molmil
Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CULLIN-3, ...
Authors:Canning, P, Cooper, C.D.O, Krojer, T, Filippakopoulos, P, Ayinampudi, V, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A.N, Structural Genomics Consortium (SGC)
Deposit date:2012-03-30
Release date:2012-05-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
4APF
DownloadVisualize
BU of 4apf by Molmil
Crystal structure of the human KLHL11-Cul3 complex at 3.1A resolution
Descriptor: CULLIN 3, KELCH-LIKE PROTEIN 11
Authors:Canning, P, Cooper, C.D.O, Krojer, T, Vollmar, M, Ugochukwu, E, Muniz, J.R.C, Ayinampudi, V, Savitsky, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A.N, Structural Genomics Consortium (SGC)
Deposit date:2012-04-02
Release date:2012-05-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
4EOZ
DownloadVisualize
BU of 4eoz by Molmil
Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain
Descriptor: Cullin-3, Speckle-type POZ protein
Authors:Prive, G.G, Errington, W.J.
Deposit date:2012-04-16
Release date:2012-05-30
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.
Structure, 20, 2012
4F52
DownloadVisualize
BU of 4f52 by Molmil
Structure of a Glomulin-RBX1-CUL1 complex
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
Authors:Duda, D.M, Olszewski, J.L, Schulman, B.A.
Deposit date:2012-05-11
Release date:2012-09-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
4HXI
DownloadVisualize
BU of 4hxi by Molmil
Crystal structure of KLHL3/Cul3 complex
Descriptor: Cullin-3, Kelch-like protein 3
Authors:Ji, A.X, Prive, G.G.
Deposit date:2012-11-10
Release date:2013-03-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.513 Å)
Cite:Crystal structure of KLHL3 in complex with Cullin3.
Plos One, 8, 2013
4JGH
DownloadVisualize
BU of 4jgh by Molmil
Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5
Descriptor: Cullin-5, Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, ...
Authors:Kim, Y.K, Kwak, M.J, Ku, B, Suh, H.Y, Joo, K, Lee, J, Jung, J.U, Oh, B.H.
Deposit date:2013-03-01
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
Acta Crystallogr.,Sect.D, 69, 2013
4N9F
DownloadVisualize
BU of 4n9f by Molmil
Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex
Descriptor: Core-binding factor subunit beta, Cullin-5, Transcription elongation factor B polypeptide 1, ...
Authors:Guo, Y.Y, Dong, L.Y, Huang, Z.W.
Deposit date:2013-10-21
Release date:2014-01-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
Nature, 505, 2014
4P5O
DownloadVisualize
BU of 4p5o by Molmil
Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action
Descriptor: Cullin-1, DCN1-like protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2014-03-18
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1071 Å)
Cite:Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8.
Cell, 157, 2014
4UI9
DownloadVisualize
BU of 4ui9 by Molmil
Atomic structure of the human Anaphase-Promoting Complex
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
Deposit date:2015-03-27
Release date:2015-06-17
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
5A31
DownloadVisualize
BU of 5a31 by Molmil
Structure of the human APC-Cdh1-Hsl1-UbcH10 complex.
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Chang, L, Zhang, Z, Yang, J, Mclaughlin, S.H, Barford, D.
Deposit date:2015-05-26
Release date:2015-11-18
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Nature, 522, 2015
5G04
DownloadVisualize
BU of 5g04 by Molmil
Structure of the human APC-Cdc20-Hsl1 complex
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
Deposit date:2016-03-16
Release date:2016-05-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5G05
DownloadVisualize
BU of 5g05 by Molmil
Cryo-EM structure of combined apo phosphorylated APC
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
Deposit date:2016-03-16
Release date:2016-05-25
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5KHR
DownloadVisualize
BU of 5khr by Molmil
Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A.
Deposit date:2016-06-15
Release date:2016-08-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon