1IWG
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CRYSTAL STRUCTURE OF BACTERIAL MULTIDRUG EFFLUX TRANSPORTER ACRB
Descriptor:AcrB
Authors:Murakami, S., Nakashima, R., Yamashita, E., Yamaguchi, A.
Deposit date:2002-05-15
Release date:2002-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of bacterial multidrug efflux transporter AcrB
NATURE, 419, 2002
1OY6
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STRUCTURAL BASIS OF THE MULTIPLE BINDING CAPACITY OF THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B
Authors:Yu, E.W., McDermott, G., Zgurskaya, H.I., Nikaido, H., Koshland Jr., D.E.
Deposit date:2003-04-03
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OY8
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STRUCTURAL BASIS OF MULTIPLE DRUG BINDING CAPACITY OF THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, RHODAMINE 6G
Authors:Yu, E.W., McDermott, G., Zgurskaya, H.I., Nikaido, H., Koshland Jr., D.E.
Deposit date:2003-04-03
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OY9
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STRUCTURAL BASIS OF MULTIPLE DRUG BINDING CAPACITY OF THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, ETHIDIUM
Authors:Yu, E.W., McDermott, G., Zgurskaya, H.I., Nikaido, H., Koshland Jr., D.E.
Deposit date:2003-04-03
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OYD
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STRUCTURAL BASIS OF MULTIPLE BINDING CAPACITY OF THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, DEQUALINIUM
Authors:Yu, E.W., MeDermott, G., Zgurskaya, H.I., Nikaido, H., Koshland Jr., D.E.
Deposit date:2003-04-03
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OYE
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STRUCTURAL BASIS OF MULTIPLE BINDING CAPACITY OF THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
Authors:Yu, E.W., McDermott, G., Zgurskaya, H.I., Nikaido, H., Koshland Jr., D.E.
Deposit date:2003-04-03
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1T9T
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-18
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
1T9U
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-18
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
1T9V
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, RHODAMINE 6G
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-18
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
1T9W
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, 6-[[(2-ETHOXY-1-NAPHTHALENYL)CARBONYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-18
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
1T9X
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, ETHIDIUM
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-19
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
1T9Y
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STRUCTURAL BASIS OF MULTIDRUG TRANSPORT BY THE ACRB MULTIDRUG EFFLUX PUMP
Descriptor:Acriflavine resistance protein B, N2-(L-PHENYLALANYL)-N1-(NAPHTHALENYL)-L-ARIGNINAMIDE
Authors:Yu, E.W., McDermott, G., Nikaido, H.
Deposit date:2004-05-19
Release date:2005-10-04
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study
J.Bacteriol., 187, 2005
2DHH
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CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM
Descriptor:ACRB
Authors:Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Nature, 443, 2006
2DR6
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CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM
Descriptor:ACRB, DOXORUBICIN
Authors:Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T.
Deposit date:2006-06-08
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Nature, 443, 2006
2DRD
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CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM
Descriptor:ACRB, (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
Authors:Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T.
Deposit date:2006-06-08
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Nature, 443, 2006
2GIF
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ASYMMETRIC STRUCTURE OF TRIMERIC ACRB FROM ESCHERICHIA COLI
Descriptor:Acriflavine resistance protein B, CITRATE ANION
Authors:Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M.
Deposit date:2006-03-28
Release date:2006-09-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism.
Science, 313, 2006
2HQC
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CONFORMATION OF THE ACRB MULTIDRUG EFFLUX PUMP IN MUTANTS OF THE PUTATIVE PROTON RELAY PATHWAY
Descriptor:Acriflavine resistance protein B
Authors:Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W.
Deposit date:2006-07-18
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway
J.Bacteriol., 188, 2006
2HQD
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CONFORMATION OF THE ACRB MULTIDRUG EFFLUX PUMP IN MUTANTS OF THE PUTATIVE PROTON RELAY PATHWAY
Descriptor:Acriflavine resistance protein B
Authors:Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W.
Deposit date:2006-07-18
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway
J.Bacteriol., 188, 2006
2HQF
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CONFORMATION OF THE ACRB MULTIDRUG EFFLUX PUMP IN MUTANTS OF THE PUTATIVE PROTON RELAY PATHWAY
Descriptor:Acriflavine resistance protein B
Authors:Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W.
Deposit date:2006-07-18
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway
J.Bacteriol., 188, 2006
2HQG
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CONFORMATION OF THE ACRB MULTIDRUG EFFLUX PUMP IN MUTANTS OF THE PUTATIVE PROTON RELAY PATHWAY
Descriptor:Acriflavine resistance protein B
Authors:Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W.
Deposit date:2006-07-18
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway
J.Bacteriol., 188, 2006
2HRT
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ASYMMETRIC STRUCTURE OF TRIMERIC ACRB FROM ESCHERICHIA COLI
Descriptor:Acriflavine resistance protein B, CITRATE ANION
Authors:Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M.
Deposit date:2006-07-20
Release date:2006-09-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism.
Science, 313, 2006
2I6W
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CRYSTAL STRUCTURE OF THE MULTIDRUG EFFLUX TRANSPORTER ACRB
Descriptor:Acriflavine resistance protein B
Authors:Das, D., Xu, Q.S., Kim, S.H.
Deposit date:2006-08-29
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids.
J.Struct.Biol., 158, 2007
2J8S
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DRUG EXPORT PATHWAY OF MULTIDRUG EXPORTER ACRB REVEALED BY DARPIN INHIBITORS
Descriptor:ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Sennhauser, G., Amstutz, P., Briand, C., Storchenegger, O., Gruetter, M.G.
Deposit date:2006-10-27
Release date:2007-01-23
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors.
Plos Biol., 5, 2007
2RDD
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X-RAY CRYSTAL STRUCTURE OF ACRB IN COMPLEX WITH A NOVEL TRANSMEMBRANE HELIX.
Descriptor:Acriflavine resistance protein B, UPF0092 membrane protein yajC, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
Authors:Tornroth-Horsefield, S., Gourdon, P., Horsefield, R., Neutze, R.
Deposit date:2007-09-22
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist.
Structure, 15, 2007
2V50
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THE MISSING PART OF THE BACTERIAL MEXAB-OPRM SYSTEM: STRUCTURAL DETERMINATION OF THE MULTIDRUG EXPORTER MEXB
Descriptor:MULTIDRUG RESISTANCE PROTEIN MEXB, DODECYL-BETA-D-MALTOSIDE
Authors:Sennhauser, G., Bukowska, M.A., Gruetter, M.G.
Deposit date:2008-10-01
Release date:2009-05-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa.
J.Mol.Biol., 389, 2009
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