Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8OMM
DownloadVisualize
BU of 8omm by Molmil
Coproporphyrin III - LmCpfC complex soaked 3min with Fe2+
Descriptor: 1,2-ETHANEDIOL, Coproporphyrin III ferrochelatase, FE (II) ION, ...
Authors:Gabler, T, Hofbauer, S.
Deposit date:2023-03-31
Release date:2023-05-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Iron insertion into coproporphyrin III-ferrochelatase complex: Evidence for an intermediate distorted catalytic species.
Protein Sci., 32, 2023
8OFL
DownloadVisualize
BU of 8ofl by Molmil
Coproporphyrin III - LmCpfC complex soaked 4min with Fe2+
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Coproporphyrin III ferrochelatase, ...
Authors:Gabler, T, Hofbauer, S.
Deposit date:2023-03-16
Release date:2023-04-05
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Iron insertion into coproporphyrin III-ferrochelatase complex: Evidence for an intermediate distorted catalytic species.
Protein Sci., 32, 2023
8BBV
DownloadVisualize
BU of 8bbv by Molmil
Coproporphyrin III - LmCpfC complex soaked 2min with Fe2+
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Coproporphyrin III ferrochelatase, ...
Authors:Gabler, T, Hofbauer, S.
Deposit date:2022-10-14
Release date:2023-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Iron insertion into coproporphyrin III-ferrochelatase complex: Evidence for an intermediate distorted catalytic species.
Protein Sci., 32, 2023
8AW7
DownloadVisualize
BU of 8aw7 by Molmil
Structure of coproporphyrin III-LmCpfC R45L
Descriptor: Coproporphyrin III ferrochelatase, GLYCEROL, coproporphyrin III
Authors:Gabler, T, Hofbauer, S, Pfanzagl, V.
Deposit date:2022-08-29
Release date:2022-12-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
Protein Sci., 32, 2023
8AT8
DownloadVisualize
BU of 8at8 by Molmil
Structure of coproporphyrin III-LmCpfC
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Gabler, T, Hofbauer, S.
Deposit date:2022-08-22
Release date:2022-12-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
Protein Sci., 32, 2023
7L78
DownloadVisualize
BU of 7l78 by Molmil
H235C variant of Yeast Ferrochelatase
Descriptor: CHOLIC ACID, Ferrochelatase, mitochondrial
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2020-12-27
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Redox Biol, 46, 2021
7CTC
DownloadVisualize
BU of 7ctc by Molmil
FECH - inhibitor complex 1
Descriptor: 2-(4-tert-butylphenyl)-5-[(quinolin-2-ylamino)methyl]-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lee, S.J, Park, J.
Deposit date:2020-08-18
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:FECH - inhibitor complex 1
to be published
7CT7
DownloadVisualize
BU of 7ct7 by Molmil
FECH - inhibitor complex 2
Descriptor: 2-[[(4-chlorophenyl)amino]methyl]-5-propyl-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lee, S.J, Park, J.
Deposit date:2020-08-18
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:FECH - inhibitor complex 1
to be published
6SV3
DownloadVisualize
BU of 6sv3 by Molmil
Structure of coproheme-LmCpfC
Descriptor: 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Ferrochelatase, GLYCEROL
Authors:Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G.
Deposit date:2019-09-17
Release date:2019-12-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.64000869 Å)
Cite:Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase.
Febs J., 287, 2020
6RWV
DownloadVisualize
BU of 6rwv by Molmil
Structure of apo-LmCpfC
Descriptor: Ferrochelatase, GLYCEROL, PHOSPHATE ION, ...
Authors:Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G.
Deposit date:2019-06-06
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6386379 Å)
Cite:Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase.
Febs J., 287, 2020
4MK4
DownloadVisualize
BU of 4mk4 by Molmil
S197C variant of human ferrochelatase.
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A.
Deposit date:2013-09-04
Release date:2013-09-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:S197C variant of human ferrochelatase.
To be Published
4KMM
DownloadVisualize
BU of 4kmm by Molmil
M76H variant of human ferrochelatase
Descriptor: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-08
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:M76H variant of human ferrochelatase
To be Published
4KLA
DownloadVisualize
BU of 4kla by Molmil
E343D variant of human ferrochelatase
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-05-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:E343D variant of human ferrochelatase
To be Published
4KLC
DownloadVisualize
BU of 4klc by Molmil
E343D/F110A Double mutant of human ferrochelatase
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, mitochondrial, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:E343D/F110A Double mutant of human ferrochelatase
To be Published
4KLR
DownloadVisualize
BU of 4klr by Molmil
E343Q variant of human ferrochelatase
Descriptor: BICARBONATE ION, CHLORIDE ION, CHOLIC ACID, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:E343Q variant of human ferrochelatase
To be Published
3W1W
DownloadVisualize
BU of 3w1w by Molmil
Protein-drug complex
Descriptor: 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, CHOLIC ACID, ...
Authors:Ishii, R, Gupta, V, Yamaguchi, Y, Handa, H, Nureki, O.
Deposit date:2012-11-21
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Salicylic Acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity
Mol.Pharmacol., 84, 2013
4F4D
DownloadVisualize
BU of 4f4d by Molmil
F337R variant of human ferrochelatase
Descriptor: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A.
Deposit date:2012-05-10
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:F337R Variant of Human Ferrochelatase
TO BE PUBLISHED
3AQI
DownloadVisualize
BU of 3aqi by Molmil
H240A variant of human ferrochelatase
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A.
Deposit date:2010-11-03
Release date:2012-01-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:H240A variant of human ferrochelatase
To be published
3M4Z
DownloadVisualize
BU of 3m4z by Molmil
Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site
Descriptor: CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ...
Authors:Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M.
Deposit date:2010-03-12
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase
To be Published
3HCO
DownloadVisualize
BU of 3hco by Molmil
Human ferrochelatase with Cd and protoporphyrin IX bound
Descriptor: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCR
DownloadVisualize
BU of 3hcr by Molmil
Human Ferrochelatase with deuteroporphyrin and Ni Bound
Descriptor: CHLORIDE ION, CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCN
DownloadVisualize
BU of 3hcn by Molmil
Hg and protoporphyrin bound Human Ferrochelatase
Descriptor: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCP
DownloadVisualize
BU of 3hcp by Molmil
Human ferrochelatase with Mn and deuteroporphyrin bound
Descriptor: CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3GOQ
DownloadVisualize
BU of 3goq by Molmil
Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase
Descriptor: Ferrochelatase, MAGNESIUM ION
Authors:Karlberg, T, Hansson, M.D, Hansson, M, Al-Karadaghi, S.
Deposit date:2009-03-19
Release date:2010-03-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase
To be Published
2QD3
DownloadVisualize
BU of 2qd3 by Molmil
Wild type human ferrochelatase crystallized with ammonium sulfate
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon