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5AVO
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BU of 5avo by Molmil
Crystal structure of the reduced form of homoserine dehydrogenase from Sulfolobus tokodaii.
Descriptor: Homoserine dehydrogenase
Authors:Goto, M, Yoshimune, K, Kaneko, R.
Deposit date:2015-06-25
Release date:2015-11-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into activation of homoserine dehydrogenase from the archaeonSulfolobus tokodaiivia reduction.
Biochem Biophys Rep, 3, 2015
3MTJ
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BU of 3mtj by Molmil
The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A
Descriptor: Homoserine dehydrogenase, SULFATE ION
Authors:Stein, A.J, Cui, H, Chin, S, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-04-30
Release date:2010-05-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A
To be Published
7M92
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BU of 7m92 by Molmil
Crystal structure of unknown function protein protein B9J08_000055 Candida auris
Descriptor: Homoserine dehydrogenase
Authors:Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-03-30
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of unknown function protein protein B9J08_000055 Candida auris
To Be Published
1TVE
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BU of 1tve by Molmil
Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol
Descriptor: 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL, Homoserine dehydrogenase
Authors:Ejim, L, Mirza, I.A, Capone, C, Nazi, I, Jenkins, S, Chee, G.L, Berghuis, A.M, Wright, G.D.
Deposit date:2004-06-29
Release date:2004-07-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:New phenolic inhibitors of yeast homoserine dehydrogenase
Bioorg.Med.Chem., 12, 2004
6DZS
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BU of 6dzs by Molmil
Mycobacterial homoserine dehydrogenase ThrA in complex with NADP
Descriptor: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Chaton, C.T, Rodriguez, E.S, Korotkov, K.V.
Deposit date:2018-07-05
Release date:2018-07-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published
1Q7G
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BU of 1q7g by Molmil
Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
Descriptor: Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE, SODIUM ION
Authors:Jacques, S.L, Mirza, I.A, Ejim, L, Koteva, K, Hughes, D.W, Green, K, Kinach, R, Honek, J.F, Lai, H.K, Berghuis, A.M, Wright, G.D.
Deposit date:2003-08-18
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase
Chem.Biol., 10, 2003
2EJW
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BU of 2ejw by Molmil
Homoserine Dehydrogenase from Thermus thermophilus HB8
Descriptor: GLYCEROL, Homoserine dehydrogenase, MAGNESIUM ION, ...
Authors:Omi, R, Goto, M, Miyahara, I, Hirotsu, K.
Deposit date:2007-03-21
Release date:2008-02-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Homoserine Dehydrogenase from Thermus thermophilus HB8
To be Published
1EBU
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BU of 1ebu by Molmil
HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L-HOMOSERINE
Descriptor: 3-AMINOMETHYL-PYRIDINIUM-ADENINE-DINUCLEOTIDE, HOMOSERINE DEHYDROGENASE, L-HOMOSERINE, ...
Authors:DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
3C8M
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BU of 3c8m by Molmil
Crystal structure of homoserine dehydrogenase from Thermoplasma volcanium
Descriptor: Homoserine dehydrogenase, SULFATE ION
Authors:Osipiuk, J, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-02-12
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystal structure of homoserine dehydrogenase from Thermoplasma volcanium.
To be Published
1EBF
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BU of 1ebf by Molmil
HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+
Descriptor: HOMOSERINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION
Authors:DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
7F4B
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BU of 7f4b by Molmil
The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii.
Descriptor: MAGNESIUM ION, homoserine dehydrogenase
Authors:Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5, 2022
7F4C
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BU of 7f4c by Molmil
The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii.
Descriptor: 1,4-BUTANEDIOL, Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ogata, K, Kaneko, R, Kubota, T, Watanabe, K, Kurihara, E, Oshima, T, Yoshimune, K, Goto, M.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5, 2022
3ING
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BU of 3ing by Molmil
Crystal structure of Homoserine dehydrogenase (NP_394635.1) from THERMOPLASMA ACIDOPHILUM at 1.95 A resolution
Descriptor: 1,2-ETHANEDIOL, Homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-08-12
Release date:2009-09-01
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Homoserine dehydrogenase (NP_394635.1) from THERMOPLASMA ACIDOPHILUM at 1.95 A resolution
To be published
3DO5
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BU of 3do5 by Molmil
Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution
Descriptor: DI(HYDROXYETHYL)ETHER, Homoserine dehydrogenase, PHOSPHATE ION
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-07-03
Release date:2008-09-02
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution
To be published
3JSA
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BU of 3jsa by Molmil
Homoserine dehydrogenase from Thermoplasma volcanium complexed with NAD
Descriptor: Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Osipiuk, J, Nocek, B, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-09
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:X-ray crystal structure of Homoserine dehydrogenase from Thermoplasma volcanium
To be Published
4XB2
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BU of 4xb2 by Molmil
Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH
Descriptor: 319aa long hypothetical homoserine dehydrogenase, L-HOMOSERINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T.
Deposit date:2014-12-16
Release date:2015-07-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases.
Sci Rep, 5, 2015
4XB1
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BU of 4xb1 by Molmil
Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T.
Deposit date:2014-12-16
Release date:2015-07-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases.
Sci Rep, 5, 2015
4YDR
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BU of 4ydr by Molmil
Crystal structure of oxidized homoserine dehydrogenase of Sulfolobus tokodaii
Descriptor: Homoserine dehydrogenase, SODIUM ION
Authors:Goto, M, Yoshimune, K, Kaneko, R.
Deposit date:2015-02-23
Release date:2015-11-11
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into activation of homoserine dehydrogenase from the archaeonSulfolobus tokodaiivia reduction.
Biochem Biophys Rep, 3, 2015
4PG4
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BU of 4pg4 by Molmil
Crystal structure of S. aureus Homoserine Dehydrogenase at pH6.0
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Navratna, V, Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG8
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BU of 4pg8 by Molmil
Crystal structure of S. aureus Homoserine Dehydrogenase at pH8.5
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Navratna, V, Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG5
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BU of 4pg5 by Molmil
Crystal structure of S. aureus Homoserine Dehydrogenase at pH6.5
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Navratna, V, Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG6
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BU of 4pg6 by Molmil
Crystal structure of S. aureus Homoserine Dehydrogenase at pH7.0
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Navratna, V, Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG7
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BU of 4pg7 by Molmil
Crystal structure of S. aureus Homoserine Dehydrogenase at pH7.5
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Navratna, V, Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
5X9D
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BU of 5x9d by Molmil
Crystal structure of homoserine dehydrogenase in complex with L-cysteine and NAD
Descriptor: (2R)-3-[[(4S)-3-aminocarbonyl-1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4H-pyridin-4-yl]sulfanyl]-2-azanyl-propanoic acid, Homoserine dehydrogenase, L(+)-TARTARIC ACID
Authors:Goto, M, Ogata, K, Kaneko, R, Yoshimune, K.
Deposit date:2017-03-06
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex
Sci Rep, 8, 2018
5XDF
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BU of 5xdf by Molmil
Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE
Descriptor: FORMIC ACID, Homoserine dehydrogenase, L-HOMOSERINE, ...
Authors:Akai, S, Miyahara, I.
Deposit date:2017-03-28
Release date:2017-04-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic study of homoserine dehydrogenase from Thermus thermophilus HB8
To Be Published

 

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