1EBF
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HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+
Descriptor:HOMOSERINE DEHYDROGENASE, SODIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:DeLaBarre, B., Thompson, P.R., Wright, G.D., Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
1EBU
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HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L-HOMOSERINE
Descriptor:HOMOSERINE DEHYDROGENASE, SODIUM ION, 3-AMINOMETHYL-PYRIDINIUM-ADENINE-DINUCLEOTIDE, ...
Authors:DeLaBarre, B., Thompson, P.R., Wright, G.D., Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
1Q7G
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HOMOSERINE DEHYDROGENASE IN COMPLEX WITH SUICIDE INHIBITOR COMPLEX NAD-5-HYDROXY-4-OXONORVALINE
Descriptor:Homoserine dehydrogenase, SODIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE
Authors:Jacques, S.L., Mirza, I.A., Ejim, L., Koteva, K., Hughes, D.W., Green, K., Kinach, R., Honek, J.F., Lai, H.K., Berghuis, A.M., Wright, G.D.
Deposit date:2003-08-18
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase
Chem.Biol., 10, 2003
1TVE
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HOMOSERINE DEHYDROGENASE IN COMPLEX WITH 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL
Descriptor:Homoserine dehydrogenase, 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL
Authors:Ejim, L., Mirza, I.A., Capone, C., Nazi, I., Jenkins, S., Chee, G.L., Berghuis, A.M., Wright, G.D.
Deposit date:2004-06-29
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:New phenolic inhibitors of yeast homoserine dehydrogenase
Bioorg.Med.Chem., 12, 2004
2EJW
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HOMOSERINE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8
Descriptor:Homoserine dehydrogenase, MAGNESIUM ION, NITRATE ION, ...
Authors:Omi, R., Goto, M., Miyahara, I., Hirotsu, K.
Deposit date:2007-03-21
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Homoserine Dehydrogenase from Thermus thermophilus HB8
To be Published
3C8M
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CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE FROM THERMOPLASMA VOLCANIUM
Descriptor:Homoserine dehydrogenase, SULFATE ION
Authors:Osipiuk, J., Hendricks, R., Abdullah, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-02-12
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystal structure of homoserine dehydrogenase from Thermoplasma volcanium.
To be Published
3DO5
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CRYSTAL STRUCTURE OF PUTATIVE HOMOSERINE DEHYDROGENASE (NP_069768.1) FROM ARCHAEOGLOBUS FULGIDUS AT 2.20 A RESOLUTION
Descriptor:Homoserine dehydrogenase, PHOSPHATE ION, DI(HYDROXYETHYL)ETHER
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-07-03
Release date:2008-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution
To be published
3ING
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CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE (NP_394635.1) FROM THERMOPLASMA ACIDOPHILUM AT 1.95 A RESOLUTION
Descriptor:Homoserine dehydrogenase, SODIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-08-12
Release date:2009-09-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Homoserine dehydrogenase (NP_394635.1) from THERMOPLASMA ACIDOPHILUM at 1.95 A resolution
To be published
3JSA
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HOMOSERINE DEHYDROGENASE FROM THERMOPLASMA VOLCANIUM COMPLEXED WITH NAD
Descriptor:Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Osipiuk, J., Nocek, B., Hendricks, R., Abdullah, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-09
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:X-ray crystal structure of Homoserine dehydrogenase from Thermoplasma volcanium
To be Published
3MTJ
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THE CRYSTAL STRUCTURE OF A HOMOSERINE DEHYDROGENASE FROM THIOBACILLUS DENITRIFICANS TO 2.15A
Descriptor:Homoserine dehydrogenase, SULFATE ION
Authors:Stein, A.J., Cui, H., Chin, S., Savchenko, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-04-30
Release date:2010-05-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A
To be Published
4PG4
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CRYSTAL STRUCTURE OF S. AUREUS HOMOSERINE DEHYDROGENASE AT PH6.0
Descriptor:Homoserine dehydrogenase, ACETATE ION, GLYCEROL, ...
Authors:Navratna, V., Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG5
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CRYSTAL STRUCTURE OF S. AUREUS HOMOSERINE DEHYDROGENASE AT PH6.5
Descriptor:Homoserine dehydrogenase, ACETATE ION, GLYCEROL, ...
Authors:Navratna, V., Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG6
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CRYSTAL STRUCTURE OF S. AUREUS HOMOSERINE DEHYDROGENASE AT PH7.0
Descriptor:Homoserine dehydrogenase, ACETATE ION, GLYCEROL, ...
Authors:Navratna, V., Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG7
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CRYSTAL STRUCTURE OF S. AUREUS HOMOSERINE DEHYDROGENASE AT PH7.5
Descriptor:Homoserine dehydrogenase, ACETATE ION, GLYCEROL, ...
Authors:Navratna, V., Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4PG8
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CRYSTAL STRUCTURE OF S. AUREUS HOMOSERINE DEHYDROGENASE AT PH8.5
Descriptor:Homoserine dehydrogenase, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Navratna, V., Gopal, B.
Deposit date:2014-05-01
Release date:2015-05-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the catalytic mechanism of homoserine dehydrogenase.
Acta Crystallogr.,Sect.D, 71, 2015
4XB1
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HYPERTHERMOPHILIC ARCHAEAL HOMOSERINE DEHYDROGENASE IN COMPLEX WITH NADPH
Descriptor:319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ...
Authors:Sakuraba, H., Inoue, S., Yoneda, K., Ohshima, T.
Deposit date:2014-12-16
Release date:2015-07-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases
Sci Rep, 5, 2015
4XB2
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HYPERTHERMOPHILIC ARCHAEAL HOMOSERINE DEHYDROGENASE MUTANT IN COMPLEX WITH NADPH
Descriptor:319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, L-HOMOSERINE, ...
Authors:Sakuraba, H., Inoue, S., Yoneda, K., Ohshima, T.
Deposit date:2014-12-16
Release date:2015-07-15
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases
Sci Rep, 5, 2015
4YDR
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CRYSTAL STRUCTURE OF OXIDIZED HOMOSERINE DEHYDROGENASE OF SULFOLOBUS TOKODAII
Descriptor:Homoserine dehydrogenase, SODIUM ION
Authors:Goto, M., Yoshimune, K., Kaneko, R.
Deposit date:2015-02-23
Release date:2015-11-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into activation of homoserine dehydrogenase from the archaeon Sulfolobus tokodaii via reduction
Biochem Biophys Rep, 3, 2015
5AVO
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CRYSTAL STRUCTURE OF THE REDUCED FORM OF HOMOSERINE DEHYDROGENASE FROM SULFOLOBUS TOKODAII.
Descriptor:Homoserine dehydrogenase
Authors:Goto, M., Yoshimune, K., Kaneko, R.
Deposit date:2015-06-25
Release date:2015-11-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into activation of homoserine dehydrogenase from the archaeon Sulfolobus tokodaii via reduction
Biochem Biophys Rep, 3, 2015
5X9D
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CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE IN COMPLEX WITH L-CYSTEINE AND NAD
Descriptor:Homoserine dehydrogenase, (2R)-3-[[(4S)-3-aminocarbonyl-1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4H-pyridin-4-yl]sulfanyl]-2-azanyl-propanoic acid, L(+)-TARTARIC ACID
Authors:Goto, M., Ogata, K., Kaneko, R., Yoshimune, K.
Deposit date:2017-03-06
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex
Sci Rep, 8, 2018
5XDF
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HOMOSERINE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 COMPLEXED WITH HSE
Descriptor:Homoserine dehydrogenase, L-HOMOSERINE, SODIUM ION, ...
Authors:Akai, S., Miyahara, I.
Deposit date:2017-03-28
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic study of homoserine dehydrogenase from Thermus thermophilus HB8
To Be Published
6DZS
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MYCOBACTERIAL HOMOSERINE DEHYDROGENASE THRA IN COMPLEX WITH NADP
Descriptor:Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Chaton, C.T., Rodriguez, E.S., Korotkov, K.V.
Deposit date:2018-07-05
Release date:2018-07-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published
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