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8SGD
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BU of 8sgd by Molmil
Crystal Structure of CDC3(G) - CDC10(Delta 1-10) heterocomplex from Saccharomyces cerevisiae
Descriptor: CDC10 isoform 1, CDC3 isoform 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Saladino, G.C.R, Leonardo, D.A, Pereira, H.M, Garratt, R.C.
Deposit date:2023-04-12
Release date:2023-06-28
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly.
J.Struct.Biol., 215, 2023
7M6J
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BU of 7m6j by Molmil
Human Septin Hexameric Complex SEPT2G/SEPT6/SEPT7 by Single Particle Cryo-EM
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Mendonca, D.C, Pereira, H.M, van Heel, M, Portugal, R.V, Garratt, R.C.
Deposit date:2021-03-25
Release date:2021-07-07
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:An atomic model for the human septin hexamer by cryo-EM.
J.Mol.Biol., 433, 2021
5IRR
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BU of 5irr by Molmil
Crystal structure of Septin GTPase domain from Chlamydomonas reinhardtii
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-like protein
Authors:Pinto, A.P.A, Pereira, H.M, Navarro, M.V.A.S, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U.
Deposit date:2016-03-14
Release date:2017-04-26
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii.
J. Biol. Chem., 292, 2017
8FWP
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BU of 8fwp by Molmil
Crystal Structure of CDC10 - CDC3 heterocomplex from Saccharomyces cerevisiae
Descriptor: Cell division control protein 10, Cell division control protein 3, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Silva, R.M, Leonardo, D.A, Pereira, H.M, Garratt, R.C.
Deposit date:2023-01-23
Release date:2023-07-05
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly.
J.Struct.Biol., 215, 2023
8PFH
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BU of 8pfh by Molmil
Crystal structure of the yeast septin complex Shs1-Cdc12-Cdc3-Cdc10
Descriptor: CDC10 isoform 1, CDC12 isoform 1, Cell division control protein 3, ...
Authors:Grupp, B, Denkhaus, L, Gerhardt, S, Gronemeyer, T.
Deposit date:2023-06-16
Release date:2023-12-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity.
Commun Biol, 7, 2024
8DKT
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BU of 8dkt by Molmil
Crystal Structure of Septin1 - Septin2 heterocomplex from Drosophila melanogaster
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:de Freitas, A.F, Leonardo, D.A, Cavini, I.A, Pereira, H.M, Garratt, R.C.
Deposit date:2022-07-06
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conservation and divergence of the G-interfaces of Drosophila melanogaster septins.
Cytoskeleton (Hoboken), 80, 2023
3FTQ
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BU of 3ftq by Molmil
Crystal structure of Septin 2 in complex with GppNHp and Mg2+
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Septin-2
Authors:Sirajuddin, M, Wittinghofer, A.
Deposit date:2009-01-13
Release date:2009-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:GTP-induced conformational changes in septins and implications for function
Proc.Natl.Acad.Sci.USA, 106, 2009
4KVA
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BU of 4kva by Molmil
GTPase domain of Septin 10 from Schistosoma mansoni in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Septin
Authors:Zeraik, A.E, Pereira, H.M, Santos, Y.V, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U, Demarco, R.
Deposit date:2013-05-22
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide.
J.Biol.Chem., 289, 2014
4KV9
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BU of 4kv9 by Molmil
GTPase domain of Septin 10 from Schistosoma mansoni in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin
Authors:Zeraik, A.E, Pereira, H.M, Santos, Y.V, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U, Demarco, R.
Deposit date:2013-05-22
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide.
J.Biol.Chem., 289, 2014
5AR1
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BU of 5ar1 by Molmil
Crystal structure of Cdc11 from Saccharomyces cerevisiae
Descriptor: CELL DIVISION CONTROL PROTEIN 11
Authors:Brausemann, A, Gerhardt, S, Schott, A.K, Einsle, O, Grosse-Berkenbusch, A, Johnsson, N, Gronemeyer, T.
Deposit date:2015-09-23
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Cdc11, a Septin Subunit from Saccharomyces Cerevisiae.
J.Struct.Biol., 193, 2016
3T5D
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BU of 3t5d by Molmil
Crystal structure of Septin 7 in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-7
Authors:Zent, E, Wittinghofer, A.
Deposit date:2011-07-27
Release date:2011-08-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and biochemical properties of Sept7, a unique septin required for filament formation.
Biol.Chem., 392, 2011
4YQF
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BU of 4yqf by Molmil
GTPase domain of Human Septin 9
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-9
Authors:Matos, S.O, Leonardo, D.A, Macedo, J.N, Pereira, H.M, Araujo, A.P.U, Garratt, R.C.
Deposit date:2015-03-13
Release date:2016-03-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:GTPase domain of Human Septin 9
To Be Published
3SOP
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BU of 3sop by Molmil
Crystal Structure Of Human Septin 3 GTPase Domain
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Neuronal-specific septin-3
Authors:Marques, I.A, Macedo, J.N.A, Pereira, H.M, Valadares, N.F, Araujo, A.P.U, Garratt, R.C.
Deposit date:2011-06-30
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.885 Å)
Cite:The structure and properties of septin 3: a possible missing link in septin filament formation.
Biochem.J., 450, 2013
4Z51
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BU of 4z51 by Molmil
High Resolution Human Septin 3 GTPase domain
Descriptor: MAGNESIUM ION, Neuronal-specific septin-3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Valadares, N.F, Macedo, J.N, Leonardo, D.A, Brandao-Neto, J, Pereira, H.M, Matos, S.O, Araujo, A.P.U, Garratt, R.C.
Deposit date:2015-04-02
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface
Iucrj, 2020
5CYP
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BU of 5cyp by Molmil
GTPase domain of Septin 9 in complex with GTP-gamma-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-9
Authors:Matos, S.S, Leonardo, D.A, Pereira, H.M, Horjales, E, Araujo, A.P.U, Garratt, R.C.
Deposit date:2015-07-30
Release date:2016-08-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface
Iucrj, 2020
5CYO
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BU of 5cyo by Molmil
High resolution Septin 9 GTPase domain in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-9
Authors:Matos, S.S, Leonardo, D.A, Pereira, H.M, Horjales, E, Araujo, A.P.U, Garratt, R.C.
Deposit date:2015-07-30
Release date:2016-08-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.0354 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface
Iucrj, 2020
4Z54
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BU of 4z54 by Molmil
High Resolution Human Septin3 GTPase domain with alpha-zero helix in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Neuronal-specific septin-3
Authors:Valadares, N.F, Macedo, J.N, Pereira, H.M, Brandao-Neto, J, Matos, S.O, Leonardo, D.A, Araujo, A.P.U, Garratt, R.C.
Deposit date:2015-04-02
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface
Iucrj, 2020
3TW4
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BU of 3tw4 by Molmil
Crystal Structure of Human Septin 7 GTPase Domain
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-7
Authors:Serrao, V.H.B, Alessandro, F, Pereira, H.M, Thiemann, O.T, Garratt, R.C.
Deposit date:2011-09-21
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal.
Febs Lett., 585, 2011
2QA5
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BU of 2qa5 by Molmil
Crystal structure of Sept2 G-domain
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-2
Authors:Sirajuddin, M, Wittinghofer, A.
Deposit date:2007-06-14
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into filament formation by mammalian septins.
Nature, 449, 2007
2QNR
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BU of 2qnr by Molmil
Human septin 2 in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-2, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M, Nedyalkova, L, Tempel, W, Landry, R, Crombet, L, Kozieradzki, I, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2007-07-19
Release date:2007-07-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human septin 2 in complex with GDP.
To be Published
2QAG
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BU of 2qag by Molmil
Crystal structure of human septin trimer 2/6/7
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Septin-2, ...
Authors:Sirajuddin, M.
Deposit date:2007-06-15
Release date:2007-08-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural insight into filament formation by mammalian septins.
Nature, 449, 2007
6UPR
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BU of 6upr by Molmil
Crystal Structure of GTPase Domain of Human Septin 2 / Septin 8 Heterocomplex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Leonardo, D.A, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C.
Deposit date:2019-10-18
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
J.Mol.Biol., 432, 2020
6UQQ
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BU of 6uqq by Molmil
Crystal Structure of GTPase Domain of Human Septin 7 / Septin 3 T282Y Heterocomplex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Neuronal-specific septin-3, Septin-7
Authors:Bragnara, G, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C.
Deposit date:2019-10-21
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
J.Mol.Biol., 432, 2020
6UPQ
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BU of 6upq by Molmil
Crystal Structure of GTPase Domain of Human Septin 2 / Septin 11 Heterocomplex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Leonardo, D.A, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C.
Deposit date:2019-10-18
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
J.Mol.Biol., 432, 2020
6UPA
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BU of 6upa by Molmil
Crystal Structure of GTPase Domain of Human Septin 2/Septin 6 Heterocomplex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rosa, H.V.D, Brandao-Neto, J, Martins, C, Araujo, A.P.U, Pereira, H.M, Garratt, R.C.
Deposit date:2019-10-17
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
J.Mol.Biol., 432, 2020

 

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