1YHT
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CRYSTAL STRUCTURE ANALYSIS OF DISPERSIN B
Descriptor:ACETIC ACID, DspB, GLYCEROL
Authors:Ramasubbu, N., Thomas, L.M., Ragunath, C., Kaplan, J.B.
Deposit date:2005-01-10
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Dispersin B, a Biofilm-releasing Glycoside Hydrolase from the Periodontopathogen Actinobacillus actinomycetemcomitans.
J.Mol.Biol., 349, 2005
2EPK
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N-ACETYL-B-D-GLUCOSAMINIDASE (GCNA) FROM STREPTOCOCCUS GORDONII
Descriptor:N-acetyl-beta-D-glucosaminidase, SULFATE ION
Authors:Langley, D.B.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2EPL
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N-ACETYL-B-D-GLUCOSAMINIDASE (GCNA) FROM STREPTOCOCCUS GORDONII
Descriptor:GLYCEROL, N-acetyl-beta-D-glucosaminidase, SULFATE ION
Authors:Langley, D.B., Harty, D.W.S., Guss, J.M., Collyer, C.A.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2EPM
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N-ACETYL-B-D-GLUCOASMINIDASE (GCNA) FROM STRETOCOCCUS GORDONII
Descriptor:GLYCEROL, MERCURY (II) ION, N-acetyl-beta-D-glucosaminidase, ...
Authors:Langley, D.B., Harty, D.W.S., Guss, J.M., Collyer, C.A.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2EPN
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N-ACETYL-B-D-GLUCOSAMINIDASE (GCNA) FROM STREPTOCOCCUS GORDONII
Descriptor:3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, N-acetyl-beta-D-glucosaminidase
Authors:Langley, D.B.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2EPO
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N-ACETYL-B-D-GLUCOSAMINIDASE (GCNA) FROM STREPTOCOCCUS GORDONII
Descriptor:ACETIC ACID, N-acetyl-beta-D-glucosaminidase
Authors:Langley, D.B.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2GK1
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X-RAY CRYSTAL STRUCTURE OF NGT-BOUND HEXA
Descriptor:3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, BETA-D-MANNOSE, Beta-hexosaminidase subunit alpha, ...
Authors:Lemieux, M.J., Mark, B.L., Cherney, M.M., Withers, S.G., Mahuran, D.J., James, M.N.
Deposit date:2006-03-31
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystallographic Structure of Human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of G(M2) Ganglioside Hydrolysis.
J.Mol.Biol., 359, 2006
2YL5
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, MAGNESIUM ION
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-05-31
Release date:2011-09-14
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
2YL6
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-05-31
Release date:2011-09-14
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
2YL8
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, ALPHA-D-MANNOSE, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-05-31
Release date:2011-09-07
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
2YL9
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, ALPHA-D-MANNOSE, BETA-D-MANNOSE, ...
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-06-01
Release date:2011-09-21
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
2YLA
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, ALPHA-D-MANNOSE, BETA-D-MANNOSE, ...
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-06-01
Release date:2011-09-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
2YLL
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INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS
Descriptor:1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Higgins, M.A., Abbott, D.W., Robb, C., Dalia, A.B., Deng, L., Weiser, J.N., Parsons, T.B., Fairbanks, A.J., Vocadlo, D.J., Boraston, A.B.
Deposit date:2011-06-02
Release date:2011-09-21
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
3RPM
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CRYSTAL STRUCTURE OF THE FIRST GH20 DOMAIN OF A NOVEL BETA-N-ACETYL-HEXOSAMINIDASE STRH FROM STREPTOCOCCUS PNEUMONIAE R6
Descriptor:Beta-N-acetyl-hexosaminidase, N-ACETYL-D-GLUCOSAMINE, PENTAETHYLENE GLYCOL
Authors:Jiang, Y.L., Yu, W.L., Zhang, J.W.
Deposit date:2011-04-27
Release date:2011-10-26
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the substrate specificity of a novel beta-N-acetylhexosaminidase StrH protein from Streptococcus pneumoniae R6
J.Biol.Chem., 286, 2011
4AZ5
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:(2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-22
Release date:2013-07-10
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZ6
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-23
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZ7
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-23
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZB
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZC
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:(2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZG
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, ACETATE ION, BETA-N-ACETYLHEXOSAMINIDASE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZH
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, LOGNAC
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-26
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZI
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, BICINE, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-26
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
5A69
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GH20C, BETA-HEXOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH GAL-PUGNAC
Descriptor:N-ACETYL-BETA-D-GLUCOSAMINIDASE, [(Z)-[(3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-ylidene]amino] N-phenylcarbamate
Authors:Cid, M., Robb, C.S., Higgins, M.A., Boraston, A.B.
Deposit date:2015-06-24
Release date:2015-09-23
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A6A
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GH20C, BETA-HEXOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH NGT
Descriptor:1,2-ETHANEDIOL, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, N-ACETYL-BETA-D-GLUCOSAMINIDASE
Authors:Cid, M., Robb, C.S., Higgins, M.A., Boraston, A.B.
Deposit date:2015-06-24
Release date:2015-09-23
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A6B
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GH20C, BETA-HEXOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH PUGNAC
Descriptor:MAGNESIUM ION, N-ACETYL-BETA-D-GLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
Authors:Cid, M., Robb, C.S., Higgins, M.A., Boraston, A.B.
Deposit date:2015-06-24
Release date:2015-09-23
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
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