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1HIC	THE NMR SOLUTION STRUCTURE OF HIRUDIN(1-51) AND COMPARISON WITH CORRESPONDING THREE-DIMENSIONAL STRUCTURES DETERMINED USING THE COMPLETE 65-RESIDUE HIRUDIN POLYPEPTIDE CHAIN Descriptor: HIRUDIN VARIANT Authors: Szyperski, T, Guntert, P, Stone, S.R, Wuthrich, K. Deposit date: 1992-04-30 Release date: 1994-01-31 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Nuclear magnetic resonance solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain. J.Mol.Biol., 228, 1992
5HIR	SOLUTION STRUCTURE OF RECOMBINANT HIRUDIN AND THE LYS-47 (RIGHT ARROW) GLU MUTANT. A NUCLEAR MAGNETIC RESONANCE AND HYBRID DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING STUDY Descriptor: HIRUDIN VARIANT-1 Authors: Clore, G.M, Gronenborn, A.M. Deposit date: 1990-01-09 Release date: 1990-01-15 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry, 28, 1989
6HIR	SOLUTION STRUCTURE OF RECOMBINANT HIRUDIN AND THE LYS-47 (RIGHT ARROW) GLU MUTANT. A NUCLEAR MAGNETIC RESONANCE AND HYBRID DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING STUDY Descriptor: HIRUDIN VARIANT-1 Authors: Clore, G.M, Gronenborn, A.M. Deposit date: 1990-01-09 Release date: 1990-01-15 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry, 28, 1989
2HIR	SOLUTION STRUCTURE OF RECOMBINANT HIRUDIN AND THE LYS-47 (RIGHT ARROW) GLU MUTANT. A NUCLEAR MAGNETIC RESONANCE AND HYBRID DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING STUDY Descriptor: HIRUDIN VARIANT-1 Authors: Clore, G.M, Gronenborn, A.M. Deposit date: 1988-12-19 Release date: 1990-01-15 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry, 28, 1989
4HIR	SOLUTION STRUCTURE OF RECOMBINANT HIRUDIN AND THE LYS-47 (RIGHT ARROW) GLU MUTANT. A NUCLEAR MAGNETIC RESONANCE AND HYBRID DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING STUDY Descriptor: HIRUDIN VARIANT-1 Authors: Clore, G.M, Gronenborn, A.M. Deposit date: 1988-12-19 Release date: 1990-01-15 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry, 28, 1989
2JOO	The NMR Solution Structure of Recombinant RGD-hirudin Descriptor: Hirudin variant-1 Authors: Song, X, Mo, W, Liu, X, Yan, X, Song, H, Dai, L. Deposit date: 2007-03-14 Release date: 2008-03-18 Last modified: 2023-12-20 Method: SOLUTION NMR Cite: The NMR solution structure of recombinant RGD-hirudin Biochem.Biophys.Res.Commun., 360, 2007
4MLF	Crystal structure for the complex of thrombin mutant D102N and hirudin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Hirudin variant-1, ... Authors: Vogt, A.D, Pozzi, N, Chen, Z, Di Cera, E. Deposit date: 2013-09-06 Release date: 2013-09-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Essential role of conformational selection in ligand binding. Biophys.Chem., 186C, 2014
3HTC	THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2 Authors: Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W. Deposit date: 1993-06-11 Release date: 1994-01-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990
2PW8	Crystal structure of sulfo-hirudin complexed to thrombin Descriptor: Hirudin variant-1, NICKEL (II) ION, SODIUM ION, ... Authors: Liu, C.C, Brustad, E, Liu, W, Schultz, P.G. Deposit date: 2007-05-10 Release date: 2007-08-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. J.Am.Chem.Soc., 129, 2007
1HRT	THE STRUCTURE OF A COMPLEX OF BOVINE ALPHA-THROMBIN AND RECOMBINANT HIRUDIN AT 2.8 ANGSTROMS RESOLUTION Descriptor: HIRUDIN, THROMBIN (LARGE SUBUNIT), THROMBIN (SMALL SUBUNIT) Authors: Vitali, J, Edwards, B.F.P. Deposit date: 1993-02-25 Release date: 1994-01-31 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution. J.Biol.Chem., 267, 1992
4HTC	THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... Authors: Tulinsky, A, Rydel, T.J, Bode, W, Huber, R. Deposit date: 1993-06-25 Release date: 1994-01-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Refined structure of the hirudin-thrombin complex. J.Mol.Biol., 221, 1991
7A0E	The Crystal Structure of Bovine Thrombin in complex with Hirudin (C6U/C14U) at 1.9 Angstroms Resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ... Authors: Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G. Deposit date: 2020-08-07 Release date: 2021-03-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Diselenide crosslinks for enhanced and simplified oxidative protein folding Commun Chem, 4, 2021
7A0D	The Crystal Structure of Bovine Thrombin in complex with Hirudin (C16U/C28U) at 1.6 Angstroms Resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ... Authors: Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G. Deposit date: 2020-08-07 Release date: 2021-03-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Diselenide crosslinks for enhanced and simplified oxidative protein folding Commun Chem, 4, 2021
7A0F	The Crystal Structure of Bovine Thrombin in complex with Hirudin (C22U/C39U) at 2.7 Angstroms Resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ... Authors: Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G. Deposit date: 2020-08-07 Release date: 2021-03-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Diselenide crosslinks for enhanced and simplified oxidative protein folding Commun Chem, 4, 2021