6XXW
 
 | | Structure of beta-D-Glucuronidase for Dictyoglomus thermophilum. | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucuronidase, ... | | Authors: | Lafite, P, Daniellou, R. | | Deposit date: | 2020-01-28 | | Release date: | 2020-07-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.851 Å) | | Cite: | Thioglycoligation of aromatic thiols using a natural glucuronide donor.
Org.Biomol.Chem., 18, 2020
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8U01
 | | Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain Containing Protein from Phocaeicola plebeius | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... | | Authors: | Kim, Y, Joachimiak, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2023-08-28 | | Release date: | 2023-09-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain
Containing Protein from Phocaeicola plebeius
To Be Published
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7SF2
 | | Crystal Structure of Beta-Galactosidase from Bacteroides cellulosilyticus | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... | | Authors: | Kim, Y, Joachimiak, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2021-10-02 | | Release date: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal Structure of Beta-Galactosidase from Bacteroides cellulosilyticus
To Be Published
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1DP0
 | | E. COLI BETA-GALACTOSIDASE AT 1.7 ANGSTROM | | Descriptor: | BETA-GALACTOSIDASE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | Deposit date: | 1999-12-22 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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1BHG
 | | HUMAN BETA-GLUCURONIDASE AT 2.6 A RESOLUTION | | Descriptor: | BETA-GLUCURONIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Jain, S, Drendel, W.B. | | Deposit date: | 1996-03-04 | | Release date: | 1997-09-17 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Structure of human beta-glucuronidase reveals candidate lysosomal targeting and active-site motifs.
Nat.Struct.Biol., 3, 1996
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7XYR
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7NIT
 | | X-ray structure of a multidomain BbgIII from Bifidobacterium bifidum | | Descriptor: | Beta-galactosidase, CALCIUM ION, GLYCEROL, ... | | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Sanchez Rodriguez, F, Rigden, D.J, Tams, J.W, Wilting, R, Vester, J.K, Longhin, E, Krogh, K.B.R, Pache, R.A, Davies, G.J, Wilson, K.S. | | Deposit date: | 2021-02-14 | | Release date: | 2021-12-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Multitasking in the gut: the X-ray structure of the multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions.
Acta Crystallogr D Struct Biol, 77, 2021
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2JE8
 | | Structure of a beta-mannosidase from Bacteroides thetaiotaomicron | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MANNOSIDASE, CHLORIDE ION, ... | | Authors: | Tailford, L.E, Money, V.A, Smith, N.L, Dumon, C, Davies, G.J, Gilbert, H.J. | | Deposit date: | 2007-01-16 | | Release date: | 2007-02-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mannose Foraging by Bacteroides Thetaiotaomicron: Structure and Specificity of the Beta-Mannosidase, Btman2A.
J.Biol.Chem., 282, 2007
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7KGZ
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5T99
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5LDR
 | | Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain in complex with galactose | | Descriptor: | ACETATE ION, Beta-D-galactosidase, CHLORIDE ION, ... | | Authors: | Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G. | | Deposit date: | 2016-06-27 | | Release date: | 2016-09-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d.
Acta Crystallogr D Struct Biol, 72, 2016
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4TTG
 | | Beta-galactosidase (E. coli) in the presence of potassium chloride. | | Descriptor: | Beta-galactosidase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Juers, D.H. | | Deposit date: | 2014-06-20 | | Release date: | 2015-03-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Elucidating factors important for monovalent cation selectivity in enzymes: E. coli beta-galactosidase as a model.
Phys Chem Chem Phys, 17, 2015
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6U7I
 | | Faecalibacterium prausnitzii Beta-glucuronidase | | Descriptor: | Beta-glucuronidase | | Authors: | Ervin, S.M, Redinbo, M.R. | | Deposit date: | 2019-09-03 | | Release date: | 2019-10-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Gut microbial beta-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens.
J.Biol.Chem., 294, 2019
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5UJ6
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4UOJ
 | | Structure of Fungal beta-mannosidase (GH2) from Trichoderma harzianum | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(3-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I. | | Deposit date: | 2014-06-04 | | Release date: | 2014-07-09 | | Last modified: | 2023-03-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Insights Into the Structure and Function of Fungal Beta-Mannosidases from Glycoside Hydrolase Family 2 Based on Multiple Crystal Structures of the Trichoderma Harzianum Enzyme.
FEBS J., 281, 2014
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1PX4
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND | | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | | Authors: | Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. | | Deposit date: | 2003-07-02 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase
Biochemistry, 42, 2003
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5N6U
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1PX3
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) | | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SODIUM ION, ... | | Authors: | Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. | | Deposit date: | 2003-07-02 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase
Biochemistry, 42, 2003
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6X1Q
 | | 1.8 Angstrom resolution structure of b-galactosidase with a 200 kV cryoARM electron microscope | | Descriptor: | Beta-galactosidase, MAGNESIUM ION, SODIUM ION | | Authors: | Merk, A, Fukumura, T, Zhu, X, Darling, J, Grisshammer, R, Ognjenovic, J, Subramaniam, S. | | Deposit date: | 2020-05-19 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (1.8 Å) | | Cite: | 1.8 angstrom resolution structure of beta-galactosidase with a 200 kV CRYO ARM electron microscope.
Iucrj, 7, 2020
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8OHX
 | | Crystal structure of Beta-glucuronidase from Escherichia coli in complex with siastatin B derived inhibitor | | Descriptor: | (3~{S},4~{S},5~{S},6~{R})-4,5,6-tris(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase | | Authors: | Armstrong, Z, Yurong, C, Wu, L, Overkleeft, H.S, Davies, G.J. | | Deposit date: | 2023-03-21 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.
J.Am.Chem.Soc., 146, 2024
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8Q7Y
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5CZK
 | | Structure of E. coli beta-glucuronidase bound with a novel, potent inhibitor 1-((6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea | | Descriptor: | 1-[(6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea, Beta-glucuronidase | | Authors: | Roberts, A.R, Wallace, B.R, Redinbo, M.R. | | Deposit date: | 2015-07-31 | | Release date: | 2015-10-14 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
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6NCZ
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6NCY
 | | Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans | | Descriptor: | Beta-glucuronidase, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Walton, W.G, Pellock, S.J, Redinbo, M.R. | | Deposit date: | 2018-12-12 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
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6NZG
 | | Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine | | Descriptor: | (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, Beta-galactosidase, CALCIUM ION, ... | | Authors: | Pellock, S.J, Jariwala, P.B, Redinbo, M.R. | | Deposit date: | 2019-02-13 | | Release date: | 2019-12-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling.
Acs Chem.Biol., 15, 2020
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