4ZPC
| Coxsackievirus B3 Polymerase - A341G mutant | Descriptor: | RNA-dependent RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZP6
| Coxsackievirus B3 Polymerase - F364A mutant | Descriptor: | Genome polyprotein, SULFATE ION | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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8C1N
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3BSO
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6KWQ
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3H5X
| Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase | Descriptor: | 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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3H5Y
| Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2 | Descriptor: | 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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4ZPB
| Coxsackievirus B3 Polymerase - F364W mutant | Descriptor: | RNA-directed RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZPD
| Coxsackievirus B3 Polymerase - A345V mutant | Descriptor: | RNA-directed RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZP9
| Coxsackievirus B3 Polymerase - F364I mutant | Descriptor: | RNA-dependent RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4WYW
| Mutant K20E of 3D polymerase from Foot-and-Mouth Disease Virus | Descriptor: | ACETATE ION, GLYCEROL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. | Deposit date: | 2014-11-18 | Release date: | 2015-05-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
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3BSN
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4WFZ
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4WFX
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8C2P
| FMDV 3D polymerase in complex with 3B3 | Descriptor: | Protein 3B-3, RNA-directed RNA polymerase 3D-POL | Authors: | Ferrer-Orta, C, Veraguer, N. | Deposit date: | 2022-12-22 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
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4QPX
| NV polymerase post-incorporation-like complex | Descriptor: | GLYCEROL, MANGANESE (II) ION, Polyprotein, ... | Authors: | Zamyatkin, D.F, Parra, F, Grochulski, P, Ng, K.K.S. | Deposit date: | 2014-06-25 | Release date: | 2015-04-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallogr.,Sect.D, 70, 2014
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4ZP8
| Coxsackievirus B3 Polymerase - F364L mutant | Descriptor: | RNA-dependent RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.894 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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1UVJ
| The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA | Descriptor: | 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | Authors: | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | Deposit date: | 2004-01-21 | Release date: | 2004-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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4ZP7
| Coxsackievirus B3 Polymerase - F364V mutant | Descriptor: | Genome polyprotein | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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1U09
| Footand Mouth Disease Virus RNA-dependent RNA polymerase | Descriptor: | polyprotein | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-13 | Release date: | 2004-08-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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4WYL
| Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. | Deposit date: | 2014-11-17 | Release date: | 2015-05-06 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
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1UVL
| The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B | Descriptor: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | Authors: | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | Deposit date: | 2004-01-21 | Release date: | 2004-02-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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1UVM
| The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A | Descriptor: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | Authors: | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | Deposit date: | 2004-01-21 | Release date: | 2004-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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4NLR
| Poliovirus Polymerase - C290S Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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4NLS
| Poliovirus Polymerase - S288A Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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