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1BUO
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BU of 1buo by Molmil
BTB DOMAIN FROM PLZF
Descriptor: PROTEIN (PROMYELOCYTIC LEUKEMIA ZINC FINGER PROTEIN PLZF)
Authors:Ahmad, K.F, Engel, C.K, Prive, G.G.
Deposit date:1998-09-04
Release date:1998-10-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the BTB domain from PLZF.
Proc.Natl.Acad.Sci.USA, 95, 1998
1CS3
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BU of 1cs3 by Molmil
STRUCTURE OF BTB/POZ TRANSCRIPTION REPRESSION DOMAIN FROM PROMELOCYTIC LEUKEMIA ZINC FINGER ONCOPROTEIN
Descriptor: GLYCEROL, MAGNESIUM ION, ZINC FINGER PROTEIN PLZF
Authors:Li, X, Rauscher III, F.J, Marmorstein, R.
Deposit date:1999-08-16
Release date:1999-08-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-function studies of the BTB/POZ transcriptional repression domain from the promyelocytic leukemia zinc finger oncoprotein.
Cancer Res., 59, 1999
1R28
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BU of 1r28 by Molmil
Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom
Descriptor: B-cell lymphoma 6 protein
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
1R29
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BU of 1r29 by Molmil
Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB Domain to 1.3 Angstrom
Descriptor: B-cell lymphoma 6 protein
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
1R2B
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BU of 1r2b by Molmil
Crystal structure of the BCL6 BTB domain complexed with a SMRT co-repressor peptide
Descriptor: B-cell lymphoma 6 protein, Nuclear receptor co-repressor 2
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
2IF5
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BU of 2if5 by Molmil
Structure of the POZ domain of human LRF, a master regulator of oncogenesis
Descriptor: PRASEODYMIUM ION, Zinc finger and BTB domain-containing protein 7A
Authors:Schubot, F.D, Waugh, D.S, Tropea, J.
Deposit date:2006-09-20
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the POZ domain of human LRF, a master regulator of oncogenesis.
Biochem.Biophys.Res.Commun., 351, 2006
2IHC
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BU of 2ihc by Molmil
Crystal structure of the bric-a-brac (BTB) domain of human BACH1
Descriptor: Transcription regulator protein BACH1
Authors:Amos, A.L, Turnbull, A.P, Bunkoczi, G, Papagrigoriou, E, Gorrec, F, Umeano, C, Bullock, A, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2006-09-26
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of the bric-a-brac (BTB) domain of human BACH1
To be Published
2NN2
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BU of 2nn2 by Molmil
Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator
Descriptor: Zinc finger and BTB domain-containing protein 7A
Authors:Stogios, P.J, Chen, L, Prive, G.G.
Deposit date:2006-10-23
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator.
Protein Sci., 16, 2007
2PPI
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BU of 2ppi by Molmil
Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin
Descriptor: Gigaxonin
Authors:Amos, A, Turnbull, A.P, Tickle, J, Keates, T, Bullock, A, Savitsky, P, Burgess-Brown, N, Debreczeni, J.E, Ugochukwu, E, Umeano, C, Pike, A.C.W, Papagrigoriou, E, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-04-30
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin.
To be Published
2Q81
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BU of 2q81 by Molmil
Crystal Structure of the Miz-1 BTB/POZ domain
Descriptor: Miz-1 protein, TETRAETHYLENE GLYCOL
Authors:Stead, M.A, Trinh, C.H, Garnett, J.A, Carr, S.B, Edwards, T.A, Wright, S.C.
Deposit date:2007-06-08
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Beta-Sheet Interaction Interface Directs the Tetramerisation of the Miz-1 POZ Domain
J.Mol.Biol., 373, 2007
2VKP
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BU of 2vkp by Molmil
Crystal structure of BTB domain from BTBD6
Descriptor: 1,2-ETHANEDIOL, BTB/POZ DOMAIN-CONTAINING PROTEIN 6, POTASSIUM ION
Authors:Cooper, C.D.O, Pike, A.C.W, Salah, E, Filippakopoulos, P, Bunkoczi, G, Elkins, J.M, von Delft, F, Gileadi, O, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S.
Deposit date:2007-12-21
Release date:2008-02-12
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Btb Domain from Btbd6
To be Published
2VPK
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BU of 2vpk by Molmil
Crystal structure of the BTB domain of human myoneurin
Descriptor: MYONEURIN
Authors:Cooper, C.D.O, Murray, J.W, Bullock, A, Pike, A.C.W, von Delft, F, Filippakopoulos, P, Salah, E, Edwards, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Knapp, S.
Deposit date:2008-02-29
Release date:2008-03-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Btb Domain of Human Myoneurin
To be Published
2YY9
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BU of 2yy9 by Molmil
Crystal structure of BTB domain from mouse HKR3
Descriptor: Zinc finger and BTB domain-containing protein 48
Authors:Kishishita, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-27
Release date:2008-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of BTB domain from mouse HKR3
To be Published
2Z8H
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BU of 2z8h by Molmil
Structure of mouse Bach1 BTB domain
Descriptor: Transcription regulator protein BACH1
Authors:Ito, N, Murayama, K.
Deposit date:2007-09-05
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of mouse Bach1 BTB domain
To be Published
3B84
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BU of 3b84 by Molmil
Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)
Descriptor: 1,2-ETHANEDIOL, UNKNOWN ATOM OR ION, Zinc finger and BTB domain-containing protein 48
Authors:Filippakopoulos, P, Bullock, A, Cooper, C, Keates, T, Salah, E, Pilka, E, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal Structure of the Human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3).
To be Published
3BIM
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BU of 3bim by Molmil
Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide
Descriptor: B-cell lymphoma 6 protein, BCL-6 corepressor
Authors:Prive, G.G, Ghetu, A.F.
Deposit date:2007-11-30
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.
Mol.Cell, 29, 2008
3E4U
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BU of 3e4u by Molmil
Crystal Structure of the Wild-Type Human BCL6 BTB/POZ Domain
Descriptor: B-cell lymphoma 6 protein
Authors:Stead, M.A, Rosbrook, G.O, Hadden, J.M, Trinh, C.H, Carr, S.B, Wright, S.C.
Deposit date:2008-08-12
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the wild-type human BCL6 POZ domain.
Acta Crystallogr.,Sect.F, 64, 2008
3FKC
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BU of 3fkc by Molmil
Crystal Structure of Human Zinc finger and BTB domain containing 33
Descriptor: Transcriptional regulator Kaiso
Authors:Filippakopoulos, P, Bullock, A, Keates, T, Burgess-Brown, N, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2008-12-16
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Zinc finger and BTB domain containing 33
To be Published
3GA1
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BU of 3ga1 by Molmil
Crystal Structure of the Human Nac1 POZ Domain
Descriptor: NITRATE ION, Nucleus accumbens-associated protein 1
Authors:Stead, M.A, Carr, S.B, Wright, S.C.
Deposit date:2009-02-16
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the human Nac1 POZ domain
Acta Crystallogr.,Sect.F, 65, 2009
3HQI
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BU of 3hqi by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
Descriptor: PucSBC1, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HTM
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BU of 3htm by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box
Descriptor: Speckle-type POZ protein
Authors:Zhuang, M, Walden, H, Schulman, B.A.
Deposit date:2009-06-11
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HU6
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BU of 3hu6 by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
Descriptor: Puckered, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-13
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HVE
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BU of 3hve by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: GigaxoninBTB/3-box
Descriptor: Gigaxonin
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-16
Release date:2009-10-27
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3I3N
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BU of 3i3n by Molmil
Crystal structure of the BTB-BACK domains of human KLHL11
Descriptor: CHLORIDE ION, Kelch-like protein 11, THIOCYANATE ION
Authors:Murray, J.W, Cooper, C.D.O, Krojer, T, Mahajan, P, Salah, E, Keates, T, Savitsky, P, Pike, A.C.W, Roos, A, Muniz, J, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
Deposit date:2009-06-30
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the BTB-BACK domains of human KLHL11
To be Published
3LBZ
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BU of 3lbz by Molmil
Crystal Structure of the BCL6 BTB domain complexed with the small molecule inhibitor 79-6
Descriptor: (2R)-2-[(5Z)-5-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanedioic acid, B-cell lymphoma 6 protein, N-[(4-bromophenyl)sulfonyl]acetamide
Authors:Ghetu, A.F, Prive, G.G.
Deposit date:2010-01-08
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo.
Cancer Cell, 17, 2010

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