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8HF1
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BU of 8hf1 by Molmil
DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
8HF0
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BU of 8hf0 by Molmil
DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
8DGJ
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BU of 8dgj by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DGI
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BU of 8dgi by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DGA
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BU of 8dga by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DG7
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BU of 8dg7 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DG5
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BU of 8dg5 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DFV
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BU of 8dfv by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa
Descriptor: CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-22
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
7ZPK
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BU of 7zpk by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPJ
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BU of 7zpj by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 isoform 1
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPI
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BU of 7zpi by Molmil
Mammalian Dicer in the "dicing state" with pre-miR-15a substrate
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (5.91 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7YZ4
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BU of 7yz4 by Molmil
Mouse endoribonuclease Dicer (composite structure)
Descriptor: Endoribonuclease Dicer
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-02-18
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7YYN
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BU of 7yyn by Molmil
Mammalian Dicer in the dicing state with pre-miR-15a substrate
Descriptor: 59-nt precursor of miR-15a, Isoform 2 of Endoribonuclease Dicer
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-02-18
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (6.21 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7YYM
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BU of 7yym by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-02-18
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4.19 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7XW3
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BU of 7xw3 by Molmil
Cryo-EM structure of an apo-form of human DICER
Descriptor: Endoribonuclease Dicer
Authors:Lee, H, Roh, S.-H.
Deposit date:2022-05-26
Release date:2023-03-08
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Structure of the human DICER-pre-miRNA complex in a dicing state.
Nature, 615, 2023
7XW2
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BU of 7xw2 by Molmil
Cryo-EM structure of human DICER-pre-miRNA in a dicing state
Descriptor: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER)
Authors:Lee, H, Roh, S.-H.
Deposit date:2022-05-26
Release date:2023-03-08
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure of the human DICER-pre-miRNA complex in a dicing state.
Nature, 615, 2023
7W0F
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BU of 7w0f by Molmil
dmDicer2-LoqsPD-dsRNA Post-dicing status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0E
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BU of 7w0e by Molmil
dmDicer2-LoqsPD-dsRNA Active-dicing status
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0D
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BU of 7w0d by Molmil
Dicer2-LoqsPD-dsRNA complex at mid-translocation state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0C
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BU of 7w0c by Molmil
Dicer2-Loqs-PD-dsRNA complex at early-translocation state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0B
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BU of 7w0b by Molmil
Dicer2-LoqsPD complex at apo status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0A
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BU of 7w0a by Molmil
dmDicer2-LoqsPD-dsRNA Dimer status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7VG3
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BU of 7vg3 by Molmil
Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA
Descriptor: CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ...
Authors:Wang, Q, Du, J.
Deposit date:2021-09-14
Release date:2021-10-27
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7VG2
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BU of 7vg2 by Molmil
Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA
Descriptor: CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ...
Authors:Wang, Q, Du, J.
Deposit date:2021-09-14
Release date:2021-10-27
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7V6C
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BU of 7v6c by Molmil
Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex
Descriptor: Dicer-2, isoform A, R2D2, ...
Authors:Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
Deposit date:2021-08-20
Release date:2022-03-23
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022

 

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