PDB: 6 resultsInfo pagesStatus searchChemie searchBIRD

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1N0W	Crystal structure of a RAD51-BRCA2 BRC repeat complex Descriptor: 1,2-ETHANEDIOL, ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE, Breast cancer type 2 susceptibility protein, ... Authors: Pellegrini, L, Yu, D.S, Lo, T, Anand, S, Lee, M, Blundell, T.L, Venkitaraman, A.R. Deposit date: 2002-10-15 Release date: 2002-11-27 Last modified: 2020-01-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Insights into DNA recombination from the structure of a RAD51-BRCA2 complex Nature, 420, 2002
6HQU	Humanised RadA mutant HumRadA22 in complex with a recombined BRC repeat 8-2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility, DNA repair and recombination protein RadA, ... Authors: Pantelejevs, T, Lindenburg, L, Hyvonen, M, Hollfelder, F. Deposit date: 2018-09-25 Release date: 2019-10-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats. Proc.Natl.Acad.Sci.USA, 118, 2021
7QV8	Leishmania infantum BRC1 repeat in complex with LiRAD51 Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA repair protein RAD51 homolog, DNA_repair_protein_BRCA2_-_putative, ... Authors: Pantelejevs, T, Hyvonen, M. Deposit date: 2022-01-20 Release date: 2022-03-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Divergent binding mode for a protozoan BRC repeat to RAD51. Biochem.J., 479, 2022
8BR9	Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22 Descriptor: 4,6-diethylpyrimidin-2-amine, ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility protein, ... Authors: Pantelejevs, T, Hyvonen, M. Deposit date: 2022-11-22 Release date: 2023-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.63 Å) Cite: A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chem Sci, 14, 2023
8C3N	Stapled peptide SP30 in complex with humanised RadA mutant HumRadA22 Descriptor: 4,6-diethylpyrimidin-2-amine, ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility protein, ... Authors: Pantelejevs, T, Hyvonen, M. Deposit date: 2022-12-27 Release date: 2023-03-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.21 Å) Cite: A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chem Sci, 14, 2023
8C3J	Stapled peptide SP2 in complex with humanised RadA mutant HumRadA22 Descriptor: 2-[(4,6-diethyl-1,3,5-triazin-2-yl)-methyl-amino]ethanoic acid, Breast cancer type 2 susceptibility protein, DNA repair and recombination protein RadA Authors: Pantelejevs, T, Hyvonen, M. Deposit date: 2022-12-26 Release date: 2023-11-29 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.02 Å) Cite: A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chem Sci, 14, 2023