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7M10
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BU of 7m10 by Molmil
PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1
Descriptor: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2021-03-11
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Biochem.J., 478, 2021
5SZC
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BU of 5szc by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.193 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
5SZB
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BU of 5szb by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Descriptor: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-11
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
5WXH
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BU of 5wxh by Molmil
Crystal structure of TAF3 PHD finger bound to H3K4me3
Descriptor: Histone H3K4me3, Transcription initiation factor TFIID subunit 3, ZINC ION
Authors:Zhao, S, Huang, J, Li, H.
Deposit date:2017-01-07
Release date:2017-08-16
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.297 Å)
Cite:Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4L7X
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BU of 4l7x by Molmil
Crystal structure of the DIDO PHD finger in complex with H3K4me3
Descriptor: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
Authors:Tong, Q, Gatchalian, J, Kutateladze, T.G.
Deposit date:2013-06-14
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
5B78
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BU of 5b78 by Molmil
Crystal structure of MOZ double PHD finger mutant-S210D/N235R in complex with histone H3 crotonylation at K14
Descriptor: Histone H3, Histone acetyltransferase KAT6A, ZINC ION
Authors:Li, H, Xiong, X.
Deposit date:2016-06-05
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2
Nat.Chem.Biol., 12, 2016
5WLF
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BU of 5wlf by Molmil
Crystal structure of the apo PPS PHD finger
Descriptor: GLYCEROL, Protein partner of snf, isoform A, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-07-26
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.
Structure, 25, 2017
3ASL
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BU of 3asl by Molmil
Structure of UHRF1 in complex with histone tail
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ...
Authors:Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
5TDR
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BU of 5tdr by Molmil
Set3 PHD finger in complex with histone H3K4me2
Descriptor: Histone H3, SET domain-containing protein 3, SODIUM ION, ...
Authors:Andrews, F.H, Ali, M, Kutateladze, T.G.
Deposit date:2016-09-19
Release date:2016-11-02
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
2PUY
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BU of 2puy by Molmil
Crystal Structure of the BHC80 PHD finger
Descriptor: Histone H3, PHD finger protein 21A, ZINC ION
Authors:Horton, J.R, Cheng, X, Collins, R.E.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
Nature, 448, 2007
3ZVZ
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BU of 3zvz by Molmil
PHD finger of human UHRF1
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ZINC ION
Authors:Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P.
Deposit date:2011-07-28
Release date:2011-11-30
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers.
Plos One, 6, 2011
2RI7
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BU of 2ri7 by Molmil
Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2 bound state
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Nucleosome-remodeling factor subunit BPTF, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
4YBM
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BU of 4ybm by Molmil
Crystal structure of TRIM24 PHD-bromodomain complexed with N-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide (7b)
Descriptor: GLYCEROL, N-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-3,4-dimethoxybenzenesulfonamide, SULFATE ION, ...
Authors:Poncet-Montange, G, Palmer, W, Jones, P.
Deposit date:2015-02-18
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
3V43
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BU of 3v43 by Molmil
Crystal structure of MOZ
Descriptor: ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ...
Authors:Qiu, Y, Li, F.
Deposit date:2011-12-14
Release date:2012-06-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
Genes Dev., 26, 2012
5B77
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BU of 5b77 by Molmil
Crystal structrue of MOZ double PHD finger in complex with histone H3 propionylation at K14
Descriptor: Histone H3, Histone acetyltransferase KAT6A, SULFATE ION, ...
Authors:Li, H, Xiong, X.
Deposit date:2016-06-05
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2
Nat.Chem.Biol., 12, 2016
2VPB
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BU of 2vpb by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
4QF3
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BU of 4qf3 by Molmil
Crystal structure of human BAZ2B PHD zinc finger in the free form
Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, ZINC ION
Authors:Tallant, C, Van Molle, I, Chirgadze, D.Y, Ciulli, A.
Deposit date:2014-05-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
4LK9
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BU of 4lk9 by Molmil
Crystal Structure of MOZ double PHD finger histone H3 tail complex
Descriptor: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-07
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
2VPG
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BU of 2vpg by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Bienz, M, Evans, P.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
5U2J
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BU of 5u2j by Molmil
MORF double PHD finger (DPF) in complex with histone H3K14bu
Descriptor: Histone H3K14bu, Histone acetyltransferase KAT6B, ZINC ION
Authors:Andrews, F.H, Klein, B.J, Kutateladze, T.G.
Deposit date:2016-11-30
Release date:2017-04-12
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition of Histone H3K14 Acylation by MORF.
Structure, 25, 2017
5VDC
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BU of 5vdc by Molmil
Crystal structure of the human DPF2 tandem PHD finger domain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, ZINC ION, ...
Authors:Huber, F.M, Davenport, A.M, Hoelz, A.
Deposit date:2017-04-01
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4LKA
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BU of 4lka by Molmil
Crystal Structure of MOZ double PHD finger histone H3K9ac complex
Descriptor: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-07
Release date:2013-10-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
8I3F
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BU of 8i3f by Molmil
Crystal structure of Rco1-Eaf3 with peptide of histone H3 N-terminal
Descriptor: Chromatin modification-related protein EAF3, Histone H3, RCO1 isoform 1, ...
Authors:Chen, Z, Xu, C.
Deposit date:2023-01-17
Release date:2023-05-31
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4.
Cell Discov, 9, 2023
7ZDD
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BU of 7zdd by Molmil
Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide.
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM33, Histone H3.X, ...
Authors:Caria, S, Duclos, S, Crespillo, S, Errey, J, Barker, J.J.
Deposit date:2022-03-29
Release date:2022-06-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.625 Å)
Cite:Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains.
Acs Chem.Biol., 17, 2022

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PDB entries from 2024-03-27

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